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X-ray microtomography is a powerful non-destructive technique allowing 3D virtual histology of resected human tissue. The achievable imaging field-of-view, is however limited by the fixed number of detector elements, enforcing the…

Hard X-ray tomography with Paganin's widespread single-distance phase retrieval filter improves contrast-to-noise ratio (CNR) while reducing spatial resolution (SR). We demonstrate that a Gaussian filter provided larger CNR at high SR with…

Medical Physics · Physics 2020-01-22 Griffin Rodgers , Georg Schulz , Hans Deyhle , Willy Kuo , Christoph Rau , Timm Weitkamp , Bert Müller

Phase-contrast and dark-field imaging are relatively new X-ray imaging modalities that provide additional information to conventional attenuation-based imaging. However, this new information comes at the price of a more complex acquisition…

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

We study convex relaxation algorithms for phase retrieval on imaging problems. We show that structural assumptions on the signal and the observations, such as sparsity, smoothness or positivity, can be exploited to both speed-up convergence…

Optimization and Control · Mathematics 2014-04-09 Fajwel Fogel , Irène Waldspurger , Alexandre d'Aspremont

X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. Single-mask differential phase contrastnimaging method stands out as a simple and effective approach…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jingcheng Yuan , Mini Das

Spectral and grating-based differential phase-contrast X-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based X-ray imaging. In the case of spectral imaging,…

Medical Physics · Physics 2020-01-31 Korbinian Mechlem , Thorsten Sellerer , Manuel Viermetz , Julia Herzen , Franz Pfeiffer

The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…

Biological Physics · Physics 2017-06-30 Daniele Ancora

3D image reconstruction from a set of X-ray projections is an important image reconstruction problem, with applications in medical imaging, industrial inspection and airport security. The innovation of X-ray emitter arrays allows for a…

Medical Physics · Physics 2016-11-23 Maria Klodt , Raphael Hauser

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

Medical Physics · Physics 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

Reconstructing the unknown spectrum of a given X-ray source is a common problem in a wide range of X-ray imaging tasks. For high-energy sources, transmission measurements are mostly used to recover the X-ray spectrum, as a solution to an…

Applied Physics · Physics 2023-07-13 Arthur Walker , Alexandre Friou , Kevin Ginsburger

A theory of random-matrix bases is presented, including expressions for orthogonality, completeness and the random-matrix synthesis of arbitrary matrices. This is applied to ghost imaging as the realization of a random-basis reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-27 David Ceddia , David M. Paganin

A common representation of a three dimensional object in computer applications, such as graphics and design, is in the form of a triangular mesh. In many instances, individual or groups of triangles in such representation need to satisfy…

Optimization and Control · Mathematics 2019-04-08 Valentin R. Koch , Hung M. Phan

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

Medical Physics · Physics 2016-11-17 Emil Y. Sidky , Rick Chartrand , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Propagation-based X-ray phase contrast enables nanoscale imaging of biological tissue by probing not only the attenuation, but also the real part of the refractive index of the sample. Since only intensities of diffracted waves can be…

Numerical Analysis · Mathematics 2017-09-11 Simon Maretzke , Thorsten Hohage

Diffusion-based inpainting can reconstruct missing image areas with high quality from sparse data, provided that their location and their values are well optimised. This is particularly useful for applications such as image compression,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Pascal Peter , Karl Schrader , Tobias Alt , Joachim Weickert

Ptychography is a popular technique to achieve diffraction limited resolution images of a two or three dimensional sample using high frame rate detectors. We introduce a relaxation of common projection algorithms to account for…

The following paper describes a method for three-dimensional (3D) reconstruction of multi-material objects based on propagation-based X-ray phase-contrast tomography (PB-CT) with phase retrieval using the homogenous form of the…

Medical Physics · Physics 2022-05-25 Darren Thompson , Yakov I. Nesterets , Konstantin M. Pavlov , Timur Gureyev

This study presents a noise-robust framework for 1-bit diffraction tomography, a novel imaging approach that relies on intensity-only binary measurements obtained through coded apertures. The proposed reconstruction scheme leverages random…

Information Theory · Computer Science 2025-05-27 Pengwen Chen , Albert Fannjiang