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Retrieval Augmented Generation (RAG) has become prevalent in question-answering (QA) tasks due to its ability of utilizing search engine to enhance the quality of long-form question-answering (LFQA). Despite the emergence of various open…

Computation and Language · Computer Science 2024-07-02 Tianchi Cai , Zhiwen Tan , Xierui Song , Tao Sun , Jiyan Jiang , Yunqi Xu , Yinger Zhang , Jinjie Gu

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

Medical question answering (QA) requires extensive access to domain-specific knowledge. A promising direction is to enhance large language models (LLMs) with external knowledge retrieved from medical corpora or parametric knowledge stored…

Computation and Language · Computer Science 2025-10-22 Lei Li , Xiao Zhou , Yingying Zhang , Xian Wu

Retrieval-Augmented Generation (RAG) aims to generate more reliable and accurate responses, by augmenting large language models (LLMs) with the external vast and dynamic knowledge. Most previous work focuses on using RAG for single-round…

Artificial Intelligence · Computer Science 2024-03-28 Linhao Ye , Zhikai Lei , Jianghao Yin , Qin Chen , Jie Zhou , Liang He

Retrieval augmented generation (RAG) has shown great power in improving Large Language Models (LLMs). However, most existing RAG-based LLMs are dedicated to retrieving single modality information, mainly text; while for many real-world…

Computation and Language · Computer Science 2025-06-09 Saptarshi Sengupta , Shuhua Yang , Paul Kwong Yu , Fali Wang , Suhang Wang

We designed a Retrieval-Augmented Generation (RAG) system to provide large language models with relevant documents for answering domain-specific questions about Pittsburgh and Carnegie Mellon University (CMU). We extracted over 1,800…

Machine Learning · Computer Science 2024-11-22 Haojia Sun , Yaqi Wang , Shuting Zhang

Retrieval-augmented generation (RAG) has emerged to address the knowledge-intensive visual question answering (VQA) task. Current methods mainly employ separate retrieval and generation modules to acquire external knowledge and generate…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Xinwei Long , Zhiyuan Ma , Ermo Hua , Kaiyan Zhang , Biqing Qi , Bowen Zhou

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

As AI chatbots gain adoption in clinical medicine, developing effective frameworks for complex, emerging diseases presents significant challenges. We developed and evaluated six Retrieval-Augmented Generation (RAG) corpus configurations for…

Artificial Intelligence · Computer Science 2025-10-20 Philip DiGiacomo , Haoyang Wang , Jinrui Fang , Yan Leng , W Michael Brode , Ying Ding

Agentic Retrieval Augmented Generation (RAG) and 'deep research' systems aim to enable autonomous search processes where Large Language Models (LLMs) iteratively refine outputs. However, applying these systems to domain-specific…

Computation and Language · Computer Science 2025-08-08 Samy Ateia , Udo Kruschwitz

We introduce a novel retrieval-augmented generation (RAG) framework tailored for multihop question answering. First, our system uses large language model (LLM) to decompose complex multihop questions into a sequence of single-hop…

Computation and Language · Computer Science 2025-08-14 Seokgi Lee

Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes…

Computation and Language · Computer Science 2024-02-07 Jaewoong Kim , Moohong Min

Question answering is a task that answers factoid questions using a large collection of documents. It aims to provide precise answers in response to the user's questions in natural language. Question answering relies on efficient passage…

Computation and Language · Computer Science 2023-08-09 Shashank Gupta

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

This thesis work falls within the framework of question answering (QA) in the biomedical domain where several specific challenges are addressed, such as specialized lexicons and terminologies, the types of treated questions, and the…

Computation and Language · Computer Science 2023-07-26 Mourad Sarrouti

Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

Computation and Language · Computer Science 2025-02-06 Seonok Kim

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by grounding responses in external knowledge during inference. However, conventiona RAG systems under-perform on structured tabular data, largely due to coarse…

Computation and Language · Computer Science 2026-05-05 Zebin Guo , Weidong Geng , Ruichen Mao

Medical retrieval-augmented generation (RAG) systems typically operate on text chunks extracted from biomedical literature, discarding the rich visual content (tables, figures, structured layouts) of original document pages. We propose…

Artificial Intelligence · Computer Science 2026-05-01 Xupeng Chen , Binbin Shi , Chenqian Le , Jiaqi Zhang , Kewen Wang , Ran Gong , Jinhan Zhang , Chihang Wang