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The ability to autonomously explore and resolve tasks with minimal human guidance is crucial for the self-development of embodied intelligence. Although reinforcement learning methods can largely ease human effort, it's challenging to…

Robotics · Computer Science 2024-12-19 Changxin Huang , Yanbin Chang , Junfan Lin , Junyang Liang , Runhao Zeng , Jianqiang Li

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

Biomolecules · Quantitative Biology 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Reinforcement Learning (RL) has emerged as a powerful paradigm for sequential decision-making and has attracted growing interest across various domains, particularly following the advent of Deep Reinforcement Learning (DRL) in 2015.…

Software Engineering · Computer Science 2025-07-18 Dong Wang , Hanmo You , Lingwei Zhu , Kaiwei Lin , Zheng Chen , Chen Yang , Junji Yu , Zan Wang , Junjie Chen

Reinforcement learning from human feedback (RLHF) has emerged as a powerful technique to make large language models (LLMs) easier to use and more effective. A core piece of the RLHF process is the training and utilization of a model of…

Computers and Society · Computer Science 2023-11-29 Nathan Lambert , Thomas Krendl Gilbert , Tom Zick

Considering the significance of proteins, computational protein science has always been a critical scientific field, dedicated to revealing knowledge and developing applications within the protein sequence-structure-function paradigm. In…

Computational Engineering, Finance, and Science · Computer Science 2025-01-28 Wenqi Fan , Yi Zhou , Shijie Wang , Yuyao Yan , Hui Liu , Qian Zhao , Le Song , Qing Li

Reinforcement learning (RL) has enabled the training of large language model (LLM) agents to interact with the environment and to solve multi-turn long-horizon tasks. However, the RL-trained agents often struggle in tasks that require…

Machine Learning · Computer Science 2026-03-10 Yulun Jiang , Liangze Jiang , Damien Teney , Michael Moor , Maria Brbic

Recent advancements in large language models (LLMs) have led to their increased application across various tasks, with reinforcement learning from human feedback (RLHF) being a crucial part of their training to align responses with user…

Computation and Language · Computer Science 2024-10-29 Ben Hauptvogel , Malte Ostendorff , Georg Rehm , Sebastian Möller

To be successful in real-world tasks, Reinforcement Learning (RL) needs to exploit the compositional, relational, and hierarchical structure of the world, and learn to transfer it to the task at hand. Recent advances in representation…

Vision-language models (VLMs) have shown remarkable abilities by integrating large language models with visual inputs. However, they often fail to utilize visual evidence adequately, either depending on linguistic priors in vision-centric…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xiaojun Guo , Runyu Zhou , Yifei Wang , Qi Zhang , Chenheng Zhang , Stefanie Jegelka , Xiaohan Wang , Jiajun Chai , Guojun Yin , Wei Lin , Yisen Wang

Existing Protein Language Models (PLMs) often suffer from limited adaptability to multiple tasks and exhibit poor generalization across diverse biological contexts. In contrast, general-purpose Large Language Models (LLMs) lack the…

Machine Learning · Computer Science 2026-02-23 Yujia Wang , Jihong Guan , Wengen Li , Shuigeng Zhou , Xuhong Wang

Parameter-shared pre-trained language models (PLMs) have emerged as a successful approach in resource-constrained environments, enabling substantial reductions in model storage and memory costs without significant performance compromise.…

Computation and Language · Computer Science 2023-10-20 Weize Chen , Xiaoyue Xu , Xu Han , Yankai Lin , Ruobing Xie , Zhiyuan Liu , Maosong Sun , Jie Zhou

While recent advances have boosted LM proficiency in linguistic benchmarks, LMs consistently struggle to reason correctly on complex tasks like mathematics. We turn to Reinforcement Learning from Human Feedback (RLHF) as a method with which…

Computation and Language · Computer Science 2023-11-13 Sarah Pan , Vladislav Lialin , Sherin Muckatira , Anna Rumshisky

Reinforcement learning (RL), a common tool in decision making, learns control policies from various experiences based on the associated cumulative return/rewards without treating them differently. Humans, on the contrary, often learn to…

Machine Learning · Computer Science 2025-11-25 Mingkang Wu , Devin White , Vernon Lawhern , Nicholas R. Waytowich , Yongcan Cao

Efficient and sustainable crop production process management is crucial to meet the growing global demand for food, fuel, and feed while minimizing environmental impacts. Traditional crop management practices, often developed through…

Systems and Control · Electrical Eng. & Systems 2024-10-15 Dong Chen , Yanbo Huang

This paper investigates Reinforcement Learning (RL) approaches to enhance the reasoning capabilities of Large Language Model (LLM) agents in long-horizon, multi-turn scenarios. Although RL algorithms such as Group Relative Policy…

Reinforcement learning (RL) is a framework for solving sequential decision-making problems. In this work, we demonstrate that, surprisingly, RL emerges during the inference time of large language models (LLMs), a phenomenon we term…

Machine Learning · Computer Science 2026-04-28 Kefan Song , Amir Moeini , Peng Wang , Lei Gong , Rohan Chandra , Shangtong Zhang , Yanjun Qi

Reinforcement learning (RL) has achieved remarkable success in real-world decision-making across diverse domains, including gaming, robotics, online advertising, public health, and natural language processing. Despite these advances, a…

Applications · Statistics 2026-01-23 Asim H. Gazi , Yongyi Guo , Daiqi Gao , Ziping Xu , Kelly W. Zhang , Susan A. Murphy

Reinforcement learning (RL) has emerged as a promising strategy for improving the reasoning capabilities of language models (LMs) in domains such as mathematics and coding. However, most modern RL algorithms were designed to target robotics…

Artificial Intelligence · Computer Science 2025-05-26 Lianghuan Huang , Shuo Li , Sagnik Anupam , Insup Lee , Osbert Bastani

Reinforcement learning (RL) algorithms aim to learn optimal decisions in unknown environments through experience of taking actions and observing the rewards gained. In some cases, the environment is not influenced by the actions of the RL…

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