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Even when driven by the same stimulus, neuronal responses are well-known to exhibit a striking level of spiking variability. In-vivo electrophysiological recordings also reveal a surprisingly large degree of variability at the subthreshold…
Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…
In the present paper, two existing nonlinear system identification methodologies are used to identify data-driven models. The first methodology focuses on identifying the system using steady-state excitations. To accomplish this, a…
Starting from the morphological-functional assumption of the fractal brain, a mathematical model is given by activating brain non-differentiable dynamics through the determinism-nondeterminism inference of the responsible mechanisms. The…
The rate coding response of a single peripheral sensory neuron in the asymptotic, near-equilibrium limit can be derived using information theory, asymptotic Bayesian statistics and a theory of complex systems. Almost no biological knowledge…
Encoding and decoding models are widely used in systems, cognitive, and computational neuroscience to make sense of brain-activity data. However, the interpretation of their results requires care. Decoding models can help reveal whether…
Following a stimulus, the neural response typically strongly varies in time and across neurons before settling to a steady-state. While classical population coding theory disregards the temporal dimension, recent works have argued that…
It has long been debated whether information in the brain is coded at the rate of neuronal spiking or at the precise timing of single spikes. Although this issue is essential to the understanding of neural signal processing, it is not…
Working memory is a cognitive function involving the storage and manipulation of latent information over brief intervals of time, thus making it crucial for context-dependent computation. Here, we use a top-down modeling approach to examine…
Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data.…
We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…
Learning and inferring features that generate sensory input is a task continuously performed by cortex. In recent years, novel algorithms and learning rules have been proposed that allow neural network models to learn such features from…
Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…
The question of how and why the phenomenon of mode connectivity occurs in training deep neural networks has gained remarkable attention in the research community. From a theoretical perspective, two possible explanations have been proposed:…
White noise methods are a powerful tool for characterizing the computation performed by neural systems. These methods allow one to identify the feature or features that a neural system extracts from a complex input, and to determine how…
Neurons encode and transmit information in spike sequences. However, despite the effort devoted to quantify their information content, little progress has been made in this regard. Here we use a nonlinear method of time-series analysis…
Understanding how brain networks learn and manage multiple tasks simultaneously is of interest in both neuroscience and artificial intelligence. In this regard, a recent research thread in theoretical neuroscience has focused on how…
Sequential neuronal activity underlies a wide range of processes in the brain. Neuroscientific evidence for neuronal sequences has been reported in domains as diverse as perception, motor control, speech, spatial navigation and memory.…
We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…
Computation in the brain involves multiple types of neurons, yet the organizing principles for how these neurons work together remain unclear. Information theory has offered explanations for how different types of neurons can optimize the…