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The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses, which mainly depends on computational fluid dynamics (CFD). However, current segmentation methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Feiyang Xiao , Yichi Zhang , Xigui Li , Yuanye Zhou , Chen Jiang , Xin Guo , Limei Han , Yuxin Li , Fengping Zhu , Yuan Cheng

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

Diabetic retinopathy (DR) is a leading cause of vision loss among middle-aged and elderly people, which significantly impacts their daily lives and mental health. To improve the efficiency of clinical screening and enable the early…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Junlai Qiu , Yunzhu Chen , Hao Zheng , Yawen Huang , Yuexiang Li

The integration of deep learning based systems in clinical practice is often impeded by challenges rooted in limited and heterogeneous medical datasets. In addition, the field has increasingly prioritized marginal performance gains on a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Sebastian Doerrich , Francesco Di Salvo , Julius Brockmann , Christian Ledig

The thrombotic microangiopathies (TMAs) manifest in renal biopsy histology with a broad spectrum of acute and chronic findings. Precise diagnostic criteria for a renal biopsy diagnosis of TMA are missing. As a first step towards a machine…

The development of multi-label deep learning models for retinal disease classification is often hindered by the scarcity of large, expertly annotated clinical datasets due to patient privacy concerns and high costs. The recent release of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Jerry Cao-Xue , Tien Comlekoglu , Keyi Xue , Guanliang Wang , Jiang Li , Gordon Laurie

In recent years, there has been a notable increase in the level of attention that is given to algorithms based on deep learning in the context of medical image segmentation. Nevertheless, the reliability of the field has been hindered due…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Sarmad Khan , Arslan Shaukat , Umer Asgher , Basim Azam

UNet has become the gold standard method for segmenting 2D medical images that any new method must be validated against. However, in recent years, several variations of the seminal UNet have been proposed with promising results. However,…

The segmentation of pelvic fracture fragments in CT and X-ray images is crucial for trauma diagnosis, surgical planning, and intraoperative guidance. However, accurately and efficiently delineating the bone fragments remains a significant…

Alzheimer's Disease (AD) is marked by significant inter-individual variability in its progression, complicating accurate prognosis and personalized care planning. This heterogeneity underscores the critical need for predictive models…

Machine Learning · Computer Science 2025-05-01 Gulsah Hancerliogullari Koksalmis , Bulent Soykan , Laura J. Brattain , Hsin-Hsiung Huang

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Background:Convolutional Neural Networks(CNN) and Vision Transformers(ViT) are the main techniques used in Medical image segmentation. However, CNN is limited to local contextual information, and ViT's quadratic complexity results in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Xuanyu Liu , Huiyun Yao , Jinggui Gao , Zhongyi Guo , Xue Zhang , Yulin Dong

U-Net and its variants have been demonstrated to work sufficiently well in biological cell tracking and segmentation. However, these methods still suffer in the presence of complex processes such as collision of cells, mitosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Deepak K. Gupta , Nathan de Bruijn , Andreas Panteli , Efstratios Gavves

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Highly accurate biomolecular structure prediction is a key component of developing biomolecular foundation models, and one of the most critical aspects of building foundation models is identifying the recipes for scaling the model. In this…

Biomolecules · Quantitative Biology 2026-01-02 Yi Zhou , Chan Lu , Yiming Ma , Wei Qu , Fei Ye , Kexin Zhang , Lan Wang , Minrui Gui , Quanquan Gu

Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Guotai Wang , Jianghao Wu , Xiangde Luo , Xinglong Liu , Kang Li , Shaoting Zhang

Background: Chronic kidney disease (CKD), a progressive disease with high morbidity and mortality, has become a significant global public health problem. Most existing models are static and fail to capture temporal trends in disease…

Machine Learning · Computer Science 2025-10-03 Jingying Ma , Jinwei Wang , Lanlan Lu , Yexiang Sun , Mengling Feng , Feifei Zhang , Peng Shen , Zhiqin Jiang , Shenda Hong , Luxia Zhang

For severely affected COVID-19 patients, it is crucial to identify high-risk patients and predict survival and need for intensive care (ICU). Most of the proposed models are not well reported making them less reproducible and prone to high…

Machine Learning · Computer Science 2024-03-29 Mahbubunnabi Tamala , Mohammad Marufur Rahmanb , Maryam Alhasimc , Mobarak Al Mulhimd , Mohamed Derichee
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