English
Related papers

Related papers: Breaking the Euclidean Barrier: Hyperboloid-Based …

200 papers

Detecting events and their evolution through time is a crucial task in natural language understanding. Recent neural approaches to event temporal relation extraction typically map events to embeddings in the Euclidean space and train a…

Computation and Language · Computer Science 2024-06-11 Xingwei Tan , Gabriele Pergola , Yulan He

Kernels on graphs have had limited options for node-level problems. To address this, we present a novel, generalized kernel for graphs with node feature data for semi-supervised learning. The kernel is derived from a regularization…

Machine Learning · Computer Science 2022-11-29 Yin-Cong Zhi , Felix L. Opolka , Yin Cheng Ng , Pietro Liò , Xiaowen Dong

This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…

Genomics · Quantitative Biology 2023-08-11 Daniel H. Um , David A. Knowles , Gail E. Kaiser

Exploring how genetic sequences shape phenotypes is a fundamental challenge in biology and a key step toward scalable, hypothesis-driven experimentation. The task is complicated by the large modality gap between sequences and phenotypes, as…

Machine Learning · Computer Science 2025-11-18 Jingquan Yan , Yuwei Miao , Lei Yu , Yuzhi Guo , Xue Xiao , Lin Xu , Junzhou Huang

We propose an automated computational algorithm for simultaneous model selection and parameter identification for the hyperelastic mechanical characterization of human brain tissue. Following the motive of the recently proposed…

Quantitative Methods · Quantitative Biology 2024-04-17 Moritz Flaschel , Huitian Yu , Nina Reiter , Jan Hinrichsen , Silvia Budday , Paul Steinmann , Siddhant Kumar , Laura De Lorenzis

We propose a framework for 2D shape analysis using positive definite kernels defined on Kendall's shape manifold. Different representations of 2D shapes are known to generate different nonlinear spaces. Due to the nonlinearity of these…

Computer Vision and Pattern Recognition · Computer Science 2014-12-16 Sadeep Jayasumana , Mathieu Salzmann , Hongdong Li , Mehrtash Harandi

The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies and biological features inherent in DNA. In this work, we…

Computational Engineering, Finance, and Science · Computer Science 2026-03-09 Qirong Yang , Yucheng Guo , Zicheng Liu , Yujie Yang , Qijin Yin , Siyuan Li , Shaomin Ji , Linlin Chao , Xiaoming Zhang , Stan Z. Li

Choosing the most adequate kernel is crucial in many Machine Learning applications. Gaussian Process is a state-of-the-art technique for regression and classification that heavily relies on a kernel function. However, in the Gaussian…

Machine Learning · Computer Science 2019-10-15 Ibai Roman , Roberto Santana , Alexander Mendiburu , Jose A. Lozano

Imaging genetics is a growing field that employs structural or functional neuroimaging techniques to study individuals with genetic risk variants potentially linked to specific illnesses. This area presents considerable challenges to…

Applications · Statistics 2024-12-31 Siqiang Su , Zhenghao Li , Long Feng , Ting Li

How a single fertilized cell gives rise to a complex array of specialized cell types in development is a central question in biology. The cells grow, divide, and acquire differentiated characteristics through poorly understood molecular…

Machine Learning · Computer Science 2025-03-26 Da Kuang , Guanwen Qiu , Junhyong Kim

Hyperbolic embeddings are a class of representation learning methods that offer competitive performances when data can be abstracted as a tree-like graph. However, in practice, learning hyperbolic embeddings of hierarchical data is…

Machine Learning · Computer Science 2024-07-24 Zhangyu Wang , Lantian Xu , Zhifeng Kong , Weilong Wang , Xuyu Peng , Enyang Zheng

In the era of foundation models and Large Language Models (LLMs), Euclidean space has been the de facto geometric setting for machine learning architectures. However, recent literature has demonstrated that this choice comes with…

Machine Learning · Computer Science 2025-11-26 Neil He , Jiahong Liu , Buze Zhang , Ngoc Bui , Ali Maatouk , Menglin Yang , Irwin King , Melanie Weber , Rex Ying

We construct a two-layered model for learning and generating sequential data that is both computationally fast and competitive with vanilla Tsetlin machines, adding numerous advantages. Through the use of hyperdimensional vector computing…

Machine Learning · Computer Science 2024-08-30 Christian D. Blakely

A main challenge in mining network-based data is finding effective ways to represent or encode graph structures so that it can be efficiently exploited by machine learning algorithms. Several methods have focused in network representation…

Social and Information Networks · Computer Science 2019-03-18 Leonardo Gutiérrez-Gómez , Jean-Charles Delvenne

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule…

Quantitative Methods · Quantitative Biology 2007-09-26 Laurent Jacob , Jean-Philippe Vert

Discovering relational structure between input features in sequence labeling models has shown to improve their accuracy in several problem settings. However, the search space of relational features is exponential in the number of basic…

Machine Learning · Computer Science 2017-05-09 Naveen Nair , Ajay Nagesh , Ganesh Ramakrishnan

Statistical analysis and inferences on spike trains are one of the central topics in neural coding. It is of great interest to understand the underlying distribution and geometric structure of given spike train data. However, a fundamental…

Neurons and Cognition · Quantitative Biology 2015-06-11 Sergiusz Wesolowski , Alexandre A. Nikonov , Robert J. Contreras , Wei Wu

Kernel-based subspace clustering, which addresses the nonlinear structures in data, is an evolving area of research. Despite noteworthy progressions, prevailing methodologies predominantly grapple with limitations relating to (i) the…

Machine Learning · Computer Science 2025-01-22 Kunpeng Xu , Lifei Chen , Shengrui Wang

In this work we present a system based on a Deep Learning approach, by using a Convolutional Neural Network, capable of classifying protein chains of amino acids based on the protein description contained in the Protein Data Bank. Each…

Machine Learning · Computer Science 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi