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Detecting events and their evolution through time is a crucial task in natural language understanding. Recent neural approaches to event temporal relation extraction typically map events to embeddings in the Euclidean space and train a…
Kernels on graphs have had limited options for node-level problems. To address this, we present a novel, generalized kernel for graphs with node feature data for semi-supervised learning. The kernel is derived from a regularization…
This paper demonstrates the utility of organized numerical representations of genes in research involving flat string gene formats (i.e., FASTA/FASTQ5). FASTA/FASTQ files have several current limitations, such as their large file sizes,…
Exploring how genetic sequences shape phenotypes is a fundamental challenge in biology and a key step toward scalable, hypothesis-driven experimentation. The task is complicated by the large modality gap between sequences and phenotypes, as…
We propose an automated computational algorithm for simultaneous model selection and parameter identification for the hyperelastic mechanical characterization of human brain tissue. Following the motive of the recently proposed…
We propose a framework for 2D shape analysis using positive definite kernels defined on Kendall's shape manifold. Different representations of 2D shapes are known to generate different nonlinear spaces. Due to the nonlinearity of these…
The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies and biological features inherent in DNA. In this work, we…
Choosing the most adequate kernel is crucial in many Machine Learning applications. Gaussian Process is a state-of-the-art technique for regression and classification that heavily relies on a kernel function. However, in the Gaussian…
Imaging genetics is a growing field that employs structural or functional neuroimaging techniques to study individuals with genetic risk variants potentially linked to specific illnesses. This area presents considerable challenges to…
How a single fertilized cell gives rise to a complex array of specialized cell types in development is a central question in biology. The cells grow, divide, and acquire differentiated characteristics through poorly understood molecular…
Hyperbolic embeddings are a class of representation learning methods that offer competitive performances when data can be abstracted as a tree-like graph. However, in practice, learning hyperbolic embeddings of hierarchical data is…
In the era of foundation models and Large Language Models (LLMs), Euclidean space has been the de facto geometric setting for machine learning architectures. However, recent literature has demonstrated that this choice comes with…
We construct a two-layered model for learning and generating sequential data that is both computationally fast and competitive with vanilla Tsetlin machines, adding numerous advantages. Through the use of hyperdimensional vector computing…
A main challenge in mining network-based data is finding effective ways to represent or encode graph structures so that it can be efficiently exploited by machine learning algorithms. Several methods have focused in network representation…
Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…
Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule…
Discovering relational structure between input features in sequence labeling models has shown to improve their accuracy in several problem settings. However, the search space of relational features is exponential in the number of basic…
Statistical analysis and inferences on spike trains are one of the central topics in neural coding. It is of great interest to understand the underlying distribution and geometric structure of given spike train data. However, a fundamental…
Kernel-based subspace clustering, which addresses the nonlinear structures in data, is an evolving area of research. Despite noteworthy progressions, prevailing methodologies predominantly grapple with limitations relating to (i) the…
In this work we present a system based on a Deep Learning approach, by using a Convolutional Neural Network, capable of classifying protein chains of amino acids based on the protein description contained in the Protein Data Bank. Each…