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Objective: Diabetic macular edema (DME) is the leading cause of severe visual impairment in patients with diabetes. Quantification of retinal fluid, particularly intraretinal fluid (IRF) and subretinal fluid (SRF), plays a critical role in…

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

Brain tumor segmentation models have aided diagnosis in recent years. However, they face MRI complexity and variability challenges, including irregular shapes and unclear boundaries, leading to noise, misclassification, and incomplete…

Melanoma, one of most dangerous types of skin cancer, re-sults in a very high mortality rate. Early detection and resection are two key points for a successful cure. Recent research has used artificial intelligence to classify melanoma and…

We are concerned with the challenge of reliably classifying and assessing intracranial aneurysms using deep learning without compromising clinical transparency. While traditional black-box models achieve high predictive accuracy, their lack…

Despite the success of convolution- and attention-based models in vision tasks, their rigid receptive fields and complex architectures limit their ability to model irregular spatial patterns and hinder interpretability, therefore posing…

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Renal tumors, especially renal cell carcinoma (RCC), show significant heterogeneity, posing challenges for diagnosis using radiology images such as MRI, echocardiograms, and CT scans. U-Net based deep learning techniques are emerging as a…

Harmonizing the analysis of data, especially of 3-D image volumes, consisting of different number of slices and annotated per volume, is a significant problem in training and using deep neural networks in various applications, including…

Accurate visualization of liver tumors and their surrounding blood vessels is essential for noninvasive diagnosis and prognosis prediction of tumors. In medical image segmentation, there is still a lack of in-depth research on the…

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research,…

Tracking and localizing objects is a central problem in computer-assisted surgery. Optical coherence tomography (OCT) can be employed as an optical tracking system, due to its high spatial and temporal resolution. Recently, 3D convolutional…

It is a challenge to segment the location and size of rectal cancer tumours through deep learning. In this paper, in order to improve the ability of extracting suffi-cient feature information in rectal tumour segmentation, attention…

Medical image segmentation has seen significant improvements with transformer models, which excel in grasping far-reaching contexts and global contextual information. However, the increasing computational demands of these models,…