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Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a 3D, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous…

Optics · Physics 2024-09-04 Carlo Bevilacqua , Robert Prevedel

Brillouin spectroscopy is a century-old technique that has recently received renewed interest, as modern instrumentation has transformed it into a powerful contactless and label-free probe of micromechanical properties for biomedical…

Instrumentation and Detectors · Physics 2020-05-27 YuChen Xiang , Carin Basirun , Joshua Chou , Majid E. Warkiani , Peter Török , Yingying Wang , Shoufei Gao , Irina V. Kabakova

Brillouin microscopy has recently emerged as powerful technique to characterize the mechanical properties of biological tissue, cell and biomaterials. However, the potential of Brillouin microscopy is currently limited to transparent…

Biological Physics · Physics 2016-05-18 Antonio Fiore , Jitao Zhang , Peng Shao , Seok Hyun Yun , Giuliano Scarcelli

We describe an easy-to-implement technique that allows for a complete experimental characterization of sub-wavelength diameter tapered optical fibers. Our method is based on a direct and fast numerical analysis of the backward Brillouin…

A direct-detection Brillouin optical time-domain reflectometry (BOTDR) is proposed and demonstrated by using an up-conversion single-photon detector and a fiber Fabry-Perot scanning interferometer (FFP-SI). Taking advantage of high…

Brillouin Microscopy is a novel label-free optical technique that enables the measurement of a material's mechanical properties at the sub-micron scale in a non-invasive and non-contact way; in the last few years, its applications in the…

Brillouin imaging is increasingly recognized to be a powerful technique that enables non-invasive measurement of the mechanical properties of cells and tissues on a microscopic scale. This provides an unprecedented tool for investigating…

Biological Physics · Physics 2020-01-22 Christine Poon , Joshua Chou , Michael Cortie , Irina Kabakova

Brillouin microscopy enables non-contact, three-dimensional mapping of viscoelasticity in living systems, yet two long-standing limitations have constrained its biological reach: the lack of high-spectral-resolution epi-detection and the…

Brillouin and Raman scattering spectroscopy are established techniques for the nondestructive contactless and label-free readout of mechanical, chemical and structural properties of condensed matter. Brillouin-Raman investigations currently…

We report a novel approach for coherent multi-photon photoemission band mapping of the entire Brillouin zone with infrared light that is readily implemented in a laboratory setting. We excite a solid state material, Ag(110), with intense…

Other Condensed Matter · Physics 2020-08-31 Andi Li , Namitha Ann James , Tianyi Wang , Zehua Wang , Hrvoje Petek , Marcel Reutzel

Brillouin microscopy is an emerging technique for all-optical biomechanical imaging without the need for physical contact with the sample or for an external mechanical stimulus. However, Brillouin microscopy often retrieves a single,…

Optics · Physics 2024-02-27 Roni Shaashoua , Tal Levy , Barak Rotblat , Alberto Bilenca

Brillouin imaging is an emerging optical elastography technique able to generate maps of the mechanical properties at microscale, with great potential in biophysical and biomedical fields. A key parameter is its spatial resolution, which is…

Optics · Physics 2020-02-28 Silvia Caponi , Daniele Fioretto , Maurizio Mattarelli

Optical spectrometers are indispensable tools across various fields, from chemical and biological sensing to astronomical observations and quantum technologies. However, the integration of spectrometers onto photonic chips has been hindered…

Noncontact Brillouin spectroscopy is a purely optical and label-free method to retrieve fundamental material viscoelastic properties. Recently, the extension to a three-dimensional imaging modality has paved the way to novel exciting…

Optics · Physics 2022-02-24 Giuseppe Antonacci , Kareem Elsayad , Dario Polli

Frequency- and time-domain Brillouin scattering spectroscopy are powerful tools to read out the mechanical properties of complex systems in material and life sciences. Indeed, coherent acoustic phonons in the time-domain method offer…

Optics · Physics 2023-01-06 Ayumu Ishijima , Shinga Okabe , Ichiro Sakuma , Keiichi Nakagawa

Brillouin microscopy, which maps elastic modulus from the frequency shift of scattered light, has evolved to a faster speed for the investigation of rapid biomechanical changes. Impulsive stimulated Brillouin scattering (ISBS) spectroscopy…

Optics · Physics 2023-12-07 Jiarui Li , Taoran Le , Hongyuan Zhang , Haoyun Wei , Yan Li

Brillouin imaging relies on the reliable extraction of subtle spectral information from hyperspectral datasets. To date, the mainstream practice has been using line fitting of spectral features to retrieve the average peak shift and…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 YuChen Xiang , Kai Ling C. Seow , Carl Paterson , Peter Török

The role and importance of mechanical properties of cells and tissues in cellular function, development as well as disease has widely been acknowledged, however standard techniques currently used to assess them exhibit intrinsic…

Biological Physics · Physics 2019-01-09 Robert Prevedel , Alba Diz-Muñoz , Giancarlo Ruocco , Giuseppe Antonacci

Brillouin spectroscopy and imaging are emerging techniques in analytical science, biophotonics and biomedicine. They are based on Brillouin light scattering from acoustic waves or phonons in the GHz range, providing a nondestructive…

Biological Physics · Physics 2021-10-12 Francesca Palombo , Daniele Fioretto

For the first time, a direct detection BOTDR is demonstrated for distributed dynamic strain sensing incorporating double-edge technique, time-division multiplexing technique and upconversion technique. The double edges are realized by using…

Instrumentation and Detectors · Physics 2017-10-04 Mingjia Shangguan , Chong Wang , Haiyun Xia , Jiawei Qiu , Guoliang Shentu , Xiankang Dou , Qiang Zhang , Jian-wei Pan
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