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Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

Deep learning-based image processing is capable of creating highly appealing results. However, it is still widely considered as a "blackbox" transformation. In medical imaging, this lack of comprehensibility of the results is a sensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 Bernhard Stimpel , Christopher Syben , Franziska Schirrmacher , Philipp Hoelter , Arnd Dörfler , Andreas Maier

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

Methods for unsupervised domain adaptation (UDA) help to improve the performance of deep neural networks on unseen domains without any labeled data. Especially in medical disciplines such as histopathology, this is crucial since large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Kevin Thandiackal , Luigi Piccinelli , Pushpak Pati , Orcun Goksel

While Hyperspectral Anomaly Detection (HAD) excels at identifying sparse targets in complex scenes, existing models remain trapped in a scalar "reconstruction-as-endpoint" paradigm. This reliance on ambiguous scalar residuals consistently…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Jijun Xiang , Tao Wang , Jiayi Wang , Pengxiang Wang , Cheng Chen , Nian Wang

The R2D2 Deep Neural Network (DNN) series was recently introduced for image formation in radio interferometry. It can be understood as a learned version of CLEAN, whose minor cycles are substituted with DNNs. We revisit R2D2 on the grounds…

Instrumentation and Methods for Astrophysics · Physics 2025-10-02 Amir Aghabiglou , Chung San Chu , Chao Tang , Arwa Dabbech , Yves Wiaux

Unfolding, in the context of high-energy particle physics, refers to the process of removing detector distortions in experimental data. The resulting unfolded measurements are straightforward to use for direct comparisons between…

Optimization methods play a central role in signal processing, serving as the mathematical foundation for inference, estimation, and control. While classical iterative optimization algorithms provide interpretability and theoretical…

Machine Learning · Computer Science 2026-04-01 Nir Shlezinger , Santiago Segarra , Yi Zhang , Dvir Avrahami , Zohar Davidov , Tirza Routtenberg , Yonina C. Eldar

Unsupervised learning enables modeling complex images without the need for annotations. The representation learned by such models can facilitate any subsequent analysis of large image datasets. However, some generative factors that cause…

Image and Video Processing · Electrical Eng. & Systems 2020-08-27 Maxime W. Lafarge , Josien P. W. Pluim , Mitko Veta

Ultrasound (US) imaging is a fast and non-invasive imaging modality which is widely used for real-time clinical imaging applications without concerning about radiation hazard. Unfortunately, it often suffers from poor visual quality from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Dimensionality reduction algorithms like principal component analysis (PCA) are workhorses of machine learning and neuroscience, but each has well-known limitations. Variants of PCA are simple and interpretable, but not flexible enough to…

Machine Learning · Computer Science 2025-12-01 John J. Vastola , Samuel J. Gershman , Kanaka Rajan

Variational methods are widely applied to ill-posed inverse problems for they have the ability to embed prior knowledge about the solution. However, the level of performance of these methods significantly depends on a set of parameters,…

Optimization and Control · Mathematics 2020-01-23 Carla Bertocchi , Emilie Chouzenoux , Marie-Caroline Corbineau , Jean-Christophe Pesquet , Marco Prato

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

Deep unfolding networks (DUNs) combine the interpretability of model-based methods with the learning ability of deep networks, yet remain limited for blind image restoration (BIR). Existing DUNs suffer from: (1) \textbf{Degradation-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Chunming He , Rihan Zhang , Zheng Chen , Bowen Yang , Chengyu Fang , Yunlong Lin , Yulun Zhang , Fengyang Xiao , Sina Farsiu

Image denoising is a fundamental task in computer vision, particularly in medical ultrasound (US) imaging, where speckle noise significantly degrades image quality. Although recent advancements in deep neural networks have led to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuesong Li , Nassir Navab , Zhongliang Jiang

In this paper, we propose a new unsupervised feature learning framework, namely Deep Sparse Coding (DeepSC), that extends sparse coding to a multi-layer architecture for visual object recognition tasks. The main innovation of the framework…

Machine Learning · Computer Science 2013-12-23 Yunlong He , Koray Kavukcuoglu , Yun Wang , Arthur Szlam , Yanjun Qi

Principal component analysis (PCA) is a fundamental tool for analyzing multivariate data. Here the focus is on dimension reduction to the principal subspace, characterized by its projection matrix. The classical principal subspace can be…

Methodology · Statistics 2026-05-29 Fabio Centofanti , Mia Hubert , Peter J. Rousseeuw

To deal with high-dimensional unlabeled datasets in many areas, principal component analysis (PCA) has become a rising technique for unsupervised feature selection (UFS). However, most existing PCA-based methods only consider the structure…

Optimization and Control · Mathematics 2025-08-15 Xianchao Xiu , Chenyi Huang , Pan Shang , Wanquan Liu

Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Weiwen Wu , Dianlin Hu , Chuang Niu , Lieza Vanden Broeke , Anthony P. H. Butler , Peng Cao , James Atlas , Alexander Chernoglazov , Varut Vardhanabhuti , Ge Wang