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This paper introduces a novel method, referred to as "hashing", which involves masking potentially bias-inducing words in large language models (LLMs) with hash-like meaningless identifiers to reduce cognitive biases and reliance on…

Computation and Language · Computer Science 2025-06-12 Milena Chadimová , Eduard Jurášek , Tomáš Kliegr

LLM-based agents are rapidly being adopted for scientific data analysis, automating tasks once limited by human time and expertise. This capability is often framed as an acceleration of discovery, but it also accelerates a familiar failure…

Artificial Intelligence · Computer Science 2026-05-21 Dionizije Fa , Marko Culjak

The history of science is punctuated by serendipitous discoveries, where unexpected observations, rather than targeted hypotheses, opened new fields of inquiry. While modern autonomous laboratories excel at accelerating hypothesis testing,…

Artificial Intelligence · Computer Science 2025-08-12 Lance Yao , Suman Samantray , Ayana Ghosh , Kevin Roccapriore , Libor Kovarik , Sarah Allec , Maxim Ziatdinov

Recent years have seen the dramatic rise of the usage of AI algorithms in pure mathematics and fundamental sciences such as theoretical physics. This is perhaps counter-intuitive since mathematical sciences require the rigorous definitions,…

History and Overview · Mathematics 2024-08-07 Yang-Hui He

Retrieval-Augmented Generation (RAG) extends large language models (LLMs) beyond parametric knowledge, yet it is unclear when iterative retrieval-reasoning loops meaningfully outperform static RAG, particularly in scientific domains with…

Computation and Language · Computer Science 2026-05-05 Mahdi Astaraki , Mohammad Arshi Saloot , Ali Shiraee Kasmaee , Hamidreza Mahyar , Soheila Samiee

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Scientific progress is driven by the deliberate articulation of what remains unknown. This study investigates the ability of large language models (LLMs) to identify research knowledge gaps in the biomedical literature. We define two…

Computation and Language · Computer Science 2025-10-30 Nourah M Salem , Elizabeth White , Michael Bada , Lawrence Hunter

Despite interdisciplinary research leading to larger and longer-term impact, most work remains confined to single-domain academic silos. Recent AI-based approaches to scientific discovery show promise for interdisciplinary research, but…

Computation and Language · Computer Science 2026-03-13 Priyanka Kargupta , Shuhaib Mehri , Dilek Hakkani-Tur , Jiawei Han

Modern scientific discovery is bottlenecked not by data scarcity, but by the inability to synthesize fragmented knowledge into actionable hypotheses. This challenge is especially acute in battery materials research, where electrochemical…

Computation and Language · Computer Science 2026-05-26 Jaeha Oh , Byungchan Kim , Ju Li , Yang Jeong Park , Jin-Sung Park

Recently, Large Language Models (LLMs) have rapidly evolved, approaching Artificial General Intelligence (AGI) while benefiting from large-scale reinforcement learning to enhance Human Alignment (HA) and Reasoning. Recent reward-based…

Machine Learning · Computer Science 2025-06-19 Xuerui Su , Shufang Xie , Guoqing Liu , Yingce Xia , Renqian Luo , Peiran Jin , Zhiming Ma , Yue Wang , Zun Wang , Yuting Liu

Reinforcement Learning (RL) has proven highly effective at enhancing the complex reasoning abilities of Large Language Models (LLMs), yet underlying mechanisms driving this success remain largely opaque. Our analysis reveals that puzzling…

Artificial Intelligence · Computer Science 2025-09-30 Haozhe Wang , Qixin Xu , Che Liu , Junhong Wu , Fangzhen Lin , Wenhu Chen

The adoption of Large Language Models (LLMs) in scientific writing promises efficiency but risks introducing informational entropy. While "hallucinated papers" are a known artifact, the systematic degradation of valid citation chains…

Computers and Society · Computer Science 2026-01-27 H. Kemal İlter

Determining whether published scientific findings can successfully be replicated is a long-standing challenge in the empirical sciences. Existing approaches for replicability assessment typically rely either on human judgment, i.e.,…

A surge in academic publications calls for automated deep research (DR) systems, but accurately evaluating them is still an open problem. First, existing benchmarks often focus narrowly on retrieval while neglecting high-level planning and…

Computation and Language · Computer Science 2026-02-02 Zhihan Guo , Feiyang Xu , Yifan Li , Muzhi Li , Shuai Zou , Jiele Wu , Han Shi , Haoli Bai , Ho-fung Leung , Irwin King

Large language models (LLMs) have demonstrated remarkable performance in text generation and knowledge-intensive question answering. Nevertheless, they are prone to producing hallucinated content, which severely undermines their reliability…

Computation and Language · Computer Science 2026-03-09 Shize Liang , Hongzhi Wang

Autonomous scientific discovery with large language model (LLM)-based agents has recently made substantial progress, demonstrating the ability to automate end-to-end research workflows. However, existing systems largely rely on…

Computational Engineering, Finance, and Science · Computer Science 2026-01-29 Tengyue Xu , Zhuoyang Qian , Gaoge Liu , Li Ling , Zhentao Zhang , Biao Wu , Shuo Zhang , Ke Lu , Wei Shi , Ziqi Wang , Zheng Feng , Yan Luo , Shu Xu , Yongjin Chen , Zhibo Feng , Zhuo Chen , Bruce Yuan , Harry Wang , Kris Chen

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

Computation and Language · Computer Science 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

Accurate evaluation of user satisfaction is critical for iterative development of conversational AI. However, for open-ended assistants, traditional A/B testing lacks reliable metrics: explicit feedback is sparse, while implicit metrics are…

Computation and Language · Computer Science 2026-01-27 Peng Sun , Xiangyu Zhang , Duan Wu