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Mental disorders impact the lives of millions of people globally, not only impeding their day-to-day lives but also markedly reducing life expectancy. This paper addresses the persistent challenge of predicting mortality in patients with…

Machine Learning · Computer Science 2023-10-19 Sean Kim , Samuel Kim

Reinforcement Learning from Human Feedback (RLHF) has emerged as a popular paradigm for capturing human intent to alleviate the challenges of hand-crafting the reward values. Despite the increasing interest in RLHF, most works learn black…

Machine Learning · Computer Science 2024-10-14 Akansha Kalra , Daniel S. Brown

We initiate a novel approach to explain the predictions and out of sample performance of random forest (RF) regression and classification models by exploiting the fact that any RF can be mathematically formulated as an adaptive weighted K…

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

Populations and Evolution · Quantitative Biology 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

Time series models with recurrent neural networks (RNNs) can have high accuracy but are unfortunately difficult to interpret as a result of feature-interactions, temporal-interactions, and non-linear transformations. Interpretability is…

Machine Learning · Computer Science 2021-09-17 Asif Rahman , Yale Chang , Jonathan Rubin

Data-driven models are central to scientific discovery. In efforts to achieve state-of-the-art model accuracy, researchers are employing increasingly complex machine learning algorithms that often outperform simple regressions in…

Materials Science · Physics 2022-12-21 Eric S. Muckley , James E. Saal , Bryce Meredig , Christopher S. Roper , John H. Martin

Understanding and inferencing Heterogeneous Treatment Effects (HTE) and Conditional Average Treatment Effects (CATE) are vital for developing personalized treatment recommendations. Many state-of-the-art approaches achieve inspiring…

Machine Learning · Computer Science 2024-08-28 Chan Hsu , Jun-Ting Wu , Yihuang Kang

The research on mortality is an active area of research for any country where the conclusions are driven from the provided data and conditions. The domain knowledge is an essential but not a mandatory skill (though some knowledge is still…

Machine Learning · Computer Science 2020-09-14 Yasir Nadeem , Awais Ahmed

Random Forest (RF) is a widely used machine learning algorithm known for its flexibility, user-friendliness, and high predictive performance across various domains. However, it is non-interpretable. This can limit its usefulness in applied…

Machine Learning · Statistics 2024-08-13 Luca Patelli , Natalia Golini , Rosaria Ignaccolo , Michela Cameletti

Random Forest (RF) is well-known as an efficient ensemble learning method in terms of predictive performance. It is also considered a Black Box because of its hundreds of deep decision trees. This lack of interpretability can be a real…

Machine Learning · Computer Science 2024-03-27 Haddouchi Maissae , Berrado Abdelaziz

Heart failure is a life-threatening condition that affects millions of people worldwide. The ability to accurately predict patient survival can aid in early intervention and improve patient outcomes. In this study, we explore the potential…

Machine Learning · Computer Science 2023-08-14 Md. Simul Hasan Talukder , Rejwan Bin Sulaiman , Mouli Bardhan Paul Angon

Decision trees are widely used for classification and regression tasks in a variety of application fields due to their interpretability and good accuracy. During the past decade, growing attention has been devoted to globally optimized…

Machine Learning · Computer Science 2025-01-28 Antonio Consolo , Edoardo Amaldi , Andrea Manno

Current research efforts largely focus on employing at most one interpretable method to elucidate machine learning (ML) model performance. However, significant barriers remain in translating these interpretability techniques into actionable…

Computers and Society · Computer Science 2025-08-05 Ling Liao , Eva Aagaard

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

Stroke remains one of the most critical global health challenges, ranking as the second leading cause of death and the third leading cause of disability worldwide. This study explores the effectiveness of machine learning algorithms in…

Machine Learning · Computer Science 2025-05-16 Anastasija Tashkova , Stefan Eftimov , Bojan Ristov , Slobodan Kalajdziski

Age estimation from facial images is typically cast as a label distribution learning or regression problem, since aging is a gradual progress. Its main challenge is the facial feature space w.r.t. ages is inhomogeneous, due to the large…

Computer Vision and Pattern Recognition · Computer Science 2019-08-26 Wei Shen , Yilu Guo , Yan Wang , Kai Zhao , Bo Wang , Alan Yuille

As a multitude of capable machine learning (ML) models become widely available in forms such as open-source software and public APIs, central questions remain regarding their use in real-world applications, especially in high-stakes…

Machine Learning · Computer Science 2024-06-03 Dimitris Bertsimas , Matthew Peroni

Interpretability of AI models allows for user safety checks to build trust in these models. In particular, decision trees (DTs) provide a global view on the learned model and clearly outlines the role of the features that are critical to…

Machine Learning · Computer Science 2023-04-13 Hector Kohler , Riad Akrour , Philippe Preux

Real-world data (RWD) gains growing interests to provide a representative sample of the population for selecting the optimal treatment options. However, existing complex black box methods for estimating individualized treatment rules (ITR)…

Methodology · Statistics 2026-01-12 Yunshu Zhang , Shu Yang , Wendy Ye , Ilya Lipkovich , Douglas E. Faries

Model trees provide an appealing way to perform interpretable machine learning for both classification and regression problems. In contrast to ``classic'' decision trees with constant values in their leaves, model trees can use linear…

Machine Learning · Computer Science 2026-03-11 Sabino Francesco Roselli , Eibe Frank