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Drug-target interaction is fundamental in understanding how drugs affect biological systems, and accurately predicting drug-target affinity (DTA) is vital for drug discovery. Recently, deep learning methods have emerged as a significant…

Machine Learning · Computer Science 2024-12-30 Minghui Li , Zikang Guo , Yang Wu , Peijin Guo , Yao Shi , Shengshan Hu , Wei Wan , Shengqing Hu

Graph contrastive learning (GCL) is a popular method for leaning graph representations by maximizing the consistency of features across augmented views. Traditional GCL methods utilize single-perspective i.e. data or model-perspective)…

Machine Learning · Computer Science 2024-06-04 Zelin Yao , Chuang Liu , Xueqi Ma , Mukun Chen , Jia Wu , Xiantao Cai , Bo Du , Wenbin Hu

Graph Convolutional Networks (GCNs) has demonstrated promising results for recommender systems, as they can effectively leverage high-order relationship. However, these methods usually encounter data sparsity issue in real-world scenarios.…

Information Retrieval · Computer Science 2023-09-21 Qian Zhao , Zhengwei Wu , Zhiqiang Zhang , Jun Zhou

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Alicia Durrer , Julia Wolleb , Florentin Bieder , Tim Sinnecker , Matthias Weigel , Robin Sandkühler , Cristina Granziera , Özgür Yaldizli , Philippe C. Cattin

Magnetic resonance imaging (MRI) exam protocols consist of multiple contrast-weighted images of the same anatomy to emphasize different tissue properties. Due to the long acquisition times required to collect fully sampled k-space…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Brett Levac , Ajil Jalal , Kannan Ramchandran , Jonathan I. Tamir

As an efficient image contrast enhancement (CE) tool, adaptive gamma correction (AGC) was previously proposed by relating gamma parameter with cumulative distribution function (CDF) of the pixel gray levels within an image. ACG deals well…

Multimedia · Computer Science 2022-08-31 Gang Cao , Lihui Huang , Huawei Tian , Xianglin Huang , Yongbin Wang , Ruicong Zhi

Early and accurate detection of glaucoma is critical to prevent irreversible vision loss. However, existing methods often rely on unimodal data and lack interpretability, limiting their clinical utility. In this paper, we present GlaBoost,…

Machine Learning · Computer Science 2025-08-07 Cheng Huang , Weizheng Xie , Karanjit Kooner , Tsengdar Lee , Jui-Kai Wang , Jia Zhang

Medical image classification has been widely adopted in medical image analysis. However, due to the difficulty of collecting and labeling data in the medical area, medical image datasets are usually highly-imbalanced. To address this…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Zhixiong Yang , Junwen Pan , Yanzhan Yang , Xiaozhou Shi , Hong-Yu Zhou , Zhicheng Zhang , Cheng Bian

Image super-resolution is one of the important computer vision techniques aiming to reconstruct high-resolution images from corresponding low-resolution ones. Most recently, deep learning-based approaches have been demonstrated for image…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Jie Cai , Zibo Meng , Chiu Man Ho

Low-dose CT (LDCT) imaging is widely used to reduce radiation exposure to mitigate high exposure side effects, but often suffers from noise and artifacts that affect diagnostic accuracy. To tackle this issue, deep learning models have been…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Taifour Yousra , Beghdadi Azeddine , Marie Luong , Zuheng Ming

In this study, we develop a physics-informed deep learning-based method to synthesize multiple brain magnetic resonance imaging (MRI) contrasts from a single five-minute acquisition and investigate its ability to generalize to arbitrary…

The success of neural networks on medical image segmentation tasks typically relies on large labeled datasets for model training. However, acquiring and manually labeling a large medical image set is resource-intensive, expensive, and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Chen Chen , Chen Qin , Cheng Ouyang , Zeju Li , Shuo Wang , Huaqi Qiu , Liang Chen , Giacomo Tarroni , Wenjia Bai , Daniel Rueckert

Early diagnosis of prostate cancer is crucial for efficient treatment. Multi-parametric Magnetic Resonance Images (mp-MRI) are widely used for lesion detection. The Prostate Imaging Reporting and Data System (PI-RADS) has standardized…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Camille Ruppli , Pietro Gori , Roberto Ardon , Isabelle Bloch

Adversarial learning methods have been proposed for a wide range of applications, but the training of adversarial models can be notoriously unstable. Effectively balancing the performance of the generator and discriminator is critical,…

Machine Learning · Computer Science 2020-08-26 Xue Bin Peng , Angjoo Kanazawa , Sam Toyer , Pieter Abbeel , Sergey Levine

Missing scans are inevitable in longitudinal studies due to either subject dropouts or failed scans. In this paper, we propose a deep learning framework to predict missing scans from acquired scans, catering to longitudinal infant studies.…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Yunzhi Huang , Sahar Ahmad , Luyi Han , Shuai Wang , Zhengwang Wu , Weili Lin , Gang Li , Li Wang , Pew-Thian Yap

Virtual screening plays a critical role in modern drug discovery by enabling the identification of promising candidate molecules for experimental validation. Traditional machine learning methods such, as Support Vector Machines (SVM) and…

Machine Learning · Computer Science 2025-04-29 Radia Berreziga , Mohammed Brahimi , Khairedine Kraim , Hamid Azzoune

Compressed sensing (CS) leverages the sparsity prior to provide the foundation for fast magnetic resonance imaging (fastMRI). However, iterative solvers for ill-posed problems hinder their adaption to time-critical applications. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Jingshuai Liu , Mehrdad Yaghoobi

Despite their consistent performance improvements, cross-modal retrieval models (e.g., CLIP) show degraded performances with retrieving keys composed of fused image-text modality (e.g., Wikipedia pages with both images and text). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Jungsoo Lee , Janghoon Cho , Hyojin Park , Munawar Hayat , Kyuwoong Hwang , Fatih Porikli , Sungha Choi