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AI research agents can now generate research ideas, design experiments, run code, and draft papers, raising the possibility of large-scale AI-assisted scientific discovery. Many current agent frameworks explicitly encourage the generation…

Computation and Language · Computer Science 2026-05-28 Yixuan Tang , Yi Yang

Artificial intelligence and machine learning are reshaping how we approach scientific discovery, not by replacing established methods but by extending what researchers can probe, predict, and design. In this roadmap we provide a…

Six years after the seminal paper on FAIR was published, researchers still struggle to understand how to implement FAIR. For many researchers FAIR promises long-term benefits for near-term effort, requires skills not yet acquired, and is…

Computers and Society · Computer Science 2023-01-25 Christine R. Kirkpatrick , Kevin L. Coakley , Julie Christopher , Ines Dutra

Recent years have seen the dramatic rise of the usage of AI algorithms in pure mathematics and fundamental sciences such as theoretical physics. This is perhaps counter-intuitive since mathematical sciences require the rigorous definitions,…

History and Overview · Mathematics 2024-08-07 Yang-Hui He

The scientific method is the cornerstone of human progress across all branches of the natural and applied sciences, from understanding the human body to explaining how the universe works. The scientific method is based on identifying…

Artificial Intelligence · Computer Science 2025-02-28 Gianmarco Mengaldo

We present the AI Cosmologist, an agentic system designed to automate cosmological/astronomical data analysis and machine learning research workflows. This implements a complete pipeline from idea generation to experimental evaluation and…

Instrumentation and Methods for Astrophysics · Physics 2025-04-07 Adam Moss

Like any field of empirical science, AI may be approached axiomatically. We formulate requirements for a general-purpose, human-level AI system in terms of postulates. We review the methodology of deep learning, examining the explicit and…

Artificial Intelligence · Computer Science 2018-06-26 Eray Özkural

DeepResearch agents represent a transformative AI paradigm, conducting expert-level research through sophisticated reasoning and multi-tool integration. However, evaluating these systems remains critically challenging due to open-ended…

Artificial Intelligence · Computer Science 2025-10-10 Tianyu Fan , Xinyao Niu , Yuxiang Zheng , Fengji Zhang , Chengen Huang , Bei Chen , Junyang Lin , Chao Huang

The promise of autonomous scientific discovery (ASD) hinges not only on answering questions, but also on knowing which questions to ask. Most recent works in ASD explore the use of large language models (LLMs) in goal-driven settings,…

Current deep-research agents run in a ''fire-and-forget'' mode: once started, they give users no way to fix errors or add expert knowledge during execution. We present ResearStudio, the first open-source framework that places real-time…

Artificial Intelligence · Computer Science 2025-11-24 Linyi Yang , Yixuan Weng

Although artificial intelligence (AI) has achieved many feats at a rapid pace, there still exist open problems and fundamental shortcomings related to performance and resource efficiency. Since AI researchers benchmark a significant…

Artificial Intelligence · Computer Science 2023-10-16 Palaash Agrawal , Cheston Tan , Heena Rathore

Existing automated research systems operate as stateless, linear pipelines -- generating outputs without maintaining any persistent understanding of the research landscape they navigate. They process papers sequentially, propose ideas…

Artificial Intelligence · Computer Science 2026-03-27 Yunbo Long

The capacity for highly complex, evidence-based, and strategically adaptive persuasion remains a formidable great challenge for artificial intelligence. Previous work, like IBM Project Debater, focused on generating persuasive speeches in…

Computation and Language · Computer Science 2025-11-25 Allen Roush , Devin Gonier , John Hines , Judah Goldfeder , Philippe Martin Wyder , Sanjay Basu , Ravid Shwartz Ziv

Recent advances in large language models (LLMs) have opened new avenues for accelerating scientific research. While models are increasingly capable of assisting with routine tasks, their ability to contribute to novel, expert-level…

We present Denario, an AI multi-agent system designed to serve as a scientific research assistant. Denario can perform many different tasks, such as generating ideas, checking the literature, developing research plans, writing and executing…

We introduce DeepSearchQA, a 900-prompt benchmark for evaluating agents on difficult multi-step information-seeking tasks across 17 different fields. Unlike traditional benchmarks that target single answer retrieval or broad-spectrum…

Analogies have been central to creative problem-solving throughout the history of science and technology. As the number of scientific papers continues to increase exponentially, there is a growing opportunity for finding diverse solutions…

Human-Computer Interaction · Computer Science 2022-06-01 Hyeonsu B. Kang , Xin Qian , Tom Hope , Dafna Shahaf , Joel Chan , Aniket Kittur

Research waste in biomedical science is driven by redundant studies, incomplete reporting, and the limited scalability of traditional evidence synthesis workflows. We present an AI co-scientist for scalable and transparent knowledge…

Artificial Intelligence · Computer Science 2026-01-21 Arya Rahgozar , Pouria Mortezaagha

Creating open-ended algorithms, which generate their own never-ending stream of novel and appropriately challenging learning opportunities, could help to automate and accelerate progress in machine learning. A recent step in this direction…

Neural and Evolutionary Computing · Computer Science 2020-04-14 Rui Wang , Joel Lehman , Aditya Rawal , Jiale Zhi , Yulun Li , Jeff Clune , Kenneth O. Stanley