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The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Healthcare automation is shaped by local procedures and organizational constraints, so agent capabilities rarely transfer unchanged across settings. Agent skills, self-contained directories that package reusable procedures for AI agents,…

Artificial Intelligence · Computer Science 2026-05-05 Gelei Xu , Ningzhi Tang , Xueyang Li , Toby Jia-Jun Li , Zhi Zheng , Wei Jin , Yiyu Shi

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

Although artificial intelligence (AI) agents are increasingly proposed to support potentially longitudinal health tasks, such as symptom management, behavior change, and patient support, most current implementations fall short of…

Artificial Intelligence · Computer Science 2026-04-30 Georgianna Lin , Rencong Jiang , Noémie Elhadad , Xuhai "Orson" Xu

Building effective clinical decision support systems requires the synthesis of complex heterogeneous multimodal data. Such modalities include temporal electronic health records data, medical images, radiology reports, and clinical notes.…

Artificial Intelligence · Computer Science 2026-05-12 Baraa Al Jorf , Farah E. Shamout

Since the onset of COVID-19, rural communities worldwide have faced significant challenges in accessing healthcare due to the migration of experienced medical professionals to urban centers. Semi-trained caregivers, such as Community Health…

Artificial Intelligence · Computer Science 2024-10-18 Agasthya Gangavarapu , Ananya Gangavarapu

As AI agents built on large language models (LLMs) become increasingly embedded in society, issues of coordination, control, delegation, and accountability are entangled with concerns over their reliability. To design and implement LLM…

Computers and Society · Computer Science 2025-12-09 R. Patrick Xian , Garry A. Gabison , Ahmed Alaa , Christoph Riedl , Grigorios G. Chrysos

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Large language models (LLMs) are increasingly used in clinical settings, raising concerns about racial bias in both generated medical text and clinical reasoning. Existing studies have identified bias in medical LLMs, but many focus on…

Computers and Society · Computer Science 2026-04-21 Sihao Xing , Zaur Gouliev

We introduce PhysicianBench, a benchmark for evaluating LLM agents on physician tasks grounded in real clinical setting within electronic health record (EHR) environments. Existing medical agent benchmarks primarily focus on static…

Requirements Engineering (RE) plays a pivotal role in software development, encompassing tasks such as requirements elicitation, analysis, specification, and change management. Despite its critical importance, RE faces challenges including…

Software Engineering · Computer Science 2024-09-04 Malik Abdul Sami , Muhammad Waseem , Zheying Zhang , Zeeshan Rasheed , Kari Systä , Pekka Abrahamsson

The emergence of Large Language Models (LLMs) has significantly advanced solutions across various domains, from political science to software development. However, these models are constrained by their training data, which is static and…

Artificial Intelligence · Computer Science 2025-09-16 Aadil Gani Ganie

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

Although traditional statistical techniques and machine learning methods have contributed significantly to genetics and, in particular, inherited disease diagnosis, they often struggle with complex, high-dimensional data, a challenge now…

Machine Learning · Computer Science 2025-08-29 Anton Changalidis , Yury Barbitoff , Yulia Nasykhova , Andrey Glotov

Global health surveillance is currently facing a challenge of Knowledge Gaps. While general-purpose AI has proliferated, it remains fundamentally unsuited for the high-stakes epidemiological domain due to chronic hallucinations and an…

Multiagent Systems · Computer Science 2026-01-06 Aniket Wattamwar , Sampson Akwafuo

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Recent advances in generative AI have led to remarkable interest in using systems that rely on large language models (LLMs) for practical applications. However, meaningful evaluation of these systems in real-world scenarios comes with a…

Artificial Intelligence · Computer Science 2025-07-22 Ethan M. Rudd , Christopher Andrews , Philip Tully