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Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

Artificial Intelligence · Computer Science 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

In the current era of big data, extracting deep insights from massive, heterogeneous, and complexly associated multi-dimensional data has become a significant challenge. Large Language Models (LLMs) perform well in natural language…

Artificial Intelligence · Computer Science 2025-11-21 Xi Wang , Xianyao Ling , Kun Li , Gang Yin , Liang Zhang , Jiang Wu , Jun Xu , Fu Zhang , Wenbo Lei , Annie Wang , Peng Gong

Schemas play a vital role in ensuring data quality and supporting usability in the Semantic Web and natural language processing. Traditionally, their creation demands substantial involvement from knowledge engineers and domain experts.…

Artificial Intelligence · Computer Science 2025-10-03 Bohui Zhang , Yuan He , Lydia Pintscher , Albert Meroño Peñuela , Elena Simperl

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Knowledge graph (KG) is an abstraction that can be extracted from text corpora and used for in-depth reasoning. Prior work has leveraged KGs to fine-tune language models (LMs), enabling domain-specific superintelligence. In this work, we…

Computation and Language · Computer Science 2026-05-28 Jake Stephen , Niraj K. Jha

Knowledge graphs (KGs) such as DBpedia, Freebase, YAGO, Wikidata, and NELL were constructed to store large-scale, real-world facts as (subject, predicate, object) triples -- that can also be modeled as a graph, where a node (a subject or an…

Databases · Computer Science 2023-05-25 Arijit Khan

Knowledge Graphs (KGs) have gained considerable attention recently from both academia and industry. In fact, incorporating graph technology and the copious of various graph datasets have led the research community to build sophisticated…

Artificial Intelligence · Computer Science 2020-06-03 Bilal Abu-Salih , Marwan Al-Tawil , Ibrahim Aljarah , Hossam Faris , Pornpit Wongthongtham

Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…

Computation and Language · Computer Science 2024-07-29 Peng Gao , Feng Gao , Jian-Cheng Ni , Yu Wang , Fei Wang

Recently, the explosion of online education platforms makes a success in encouraging us to easily access online education resources. However, most of them ignore the integration of massive unstructured information, which inevitably brings…

Computation and Language · Computer Science 2022-05-10 Jianing Wang

The "RNA world" represents a novel frontier for the study of fundamental biological processes and human diseases and is paving the way for the development of new drugs tailored to the patient's biomolecular characteristics. Although…

Applications of large open-domain knowledge graphs (KGs) to real-world problems pose many unique challenges. In this paper, we present extensions to Saga our platform for continuous construction and serving of knowledge at scale. In…

Artificial Intelligence · Computer Science 2023-05-17 Ihab F. Ilyas , JP Lacerda , Yunyao Li , Umar Farooq Minhas , Ali Mousavi , Jeffrey Pound , Theodoros Rekatsinas , Chiraag Sumanth

Large Language Models (LLMs) and Knowledge Graphs (KGs) offer a promising approach to robust and explainable Question Answering (QA). While LLMs excel at natural language understanding, they suffer from knowledge gaps and hallucinations.…

Machine Learning · Computer Science 2025-04-15 Jasper Linders , Jakub M. Tomczak

Maintaining comprehensive and up-to-date knowledge graphs (KGs) is critical for modern AI systems, but manual curation struggles to scale with the rapid growth of scientific literature. This paper presents KARMA, a novel framework employing…

Computation and Language · Computer Science 2026-01-13 Yuxing Lu , Wei Wu , Xukai Zhao , Rui Peng , Jinzhuo Wang

Knowledge graphs (KGs) have become the preferred technology for representing, sharing and adding knowledge to modern AI applications. While KGs have become a mainstream technology, the RDF/SPARQL-centric toolset for operating with them at…

In electronic health record (EHR) mining, learning high-quality representations of medical concepts (e.g., standardized diagnosis, medication, and procedure codes) is fundamental for downstream clinical prediction. However, ro bust concept…

Machine Learning · Computer Science 2026-05-05 Mohsen Nayebi Kerdabadi , Arya Hadizadeh Moghaddam , Chen Chen , Dongjie Wang , Zijun Yao

Generating synthetic text addresses the challenge of data availability in privacy-sensitive domains such as healthcare. This study explores the applicability of synthetic data in real-world medical settings. We introduce MedSyn, a novel…

Computation and Language · Computer Science 2024-09-05 Gleb Kumichev , Pavel Blinov , Yulia Kuzkina , Vasily Goncharov , Galina Zubkova , Nikolai Zenovkin , Aleksei Goncharov , Andrey Savchenko

The conventional process of building Ontologies and Knowledge Graphs (KGs) heavily relies on human domain experts to define entities and relationship types, establish hierarchies, maintain relevance to the domain, fill the ABox (or populate…

Computation and Language · Computer Science 2024-03-14 Vamsi Krishna Kommineni , Birgitta König-Ries , Sheeba Samuel

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

Artificial Intelligence · Computer Science 2016-12-08 Armando Vieira
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