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Quantum computing promises to tackle technological and industrial problems insurmountable for classical computers. However, today's quantum computers still have limited demonstrable functionality, and it is expected that scaling up to…

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

In recent years, research on near-term quantum machine learning has explored how classical machine learning algorithms endowed with access to quantum kernels (similarity measures) can outperform their purely classical counterparts. Although…

Quantum Physics · Physics 2022-06-24 Zoran Krunic , Frederik F. Flöther , George Seegan , Nathan Earnest-Noble , Omar Shehab

Quantum annealing (QA) has the potential to significantly improve solution quality and reduce time complexity in solving combinatorial optimization problems compared to classical optimization methods. However, due to the limited number of…

Quantum Physics · Physics 2025-04-09 Seongmin Kim , Sang-Woo Ahn , In-Saeng Suh , Alexander W. Dowling , Eungkyu Lee , Tengfei Luo

Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example…

Combining quantum computers with classical compute power has become a standard means for developing algorithms that are eventually supposed to beat any purely classical alternatives. While in-principle advantages for solution quality or…

Quantum Physics · Physics 2026-01-23 Simon Thelen , Wolfgang Mauerer

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Quantum Machine Learning (QML) hasn't yet demonstrated extensively and clearly its advantages compared to the classical machine learning approach. So far, there are only specific cases where some quantum-inspired techniques have achieved…

Quantum Physics · Physics 2022-11-30 Javier Mancilla , Christophe Pere

We introduce a classical-quantum hybrid approach to computation, allowing for a quadratic performance improvement in the decision process of a learning agent. In particular, a quantum routine is described, which encodes on a quantum…

Quantum Physics · Physics 2023-03-22 A. Sannia , A. Giordano , N. Lo Gullo , C. Mastroianni , F. Plastina

We assess the prospects for algorithms within the general framework of quantum annealing (QA) to achieve a quantum speedup relative to classical state of the art methods in combinatorial optimization and related sampling tasks. We argue for…

Quantum Physics · Physics 2021-06-22 E. J. Crosson , D. A. Lidar

Genetic algorithms are highly effective optimization techniques for many computationally challenging problems, including combinatorial optimization tasks like portfolio optimization. Quantum computing has also shown potential in addressing…

Emerging Technologies · Computer Science 2025-04-28 Mohammad Kashfi Haghighi , Matthieu Fortin-Deschênes , Christophe Pere , Mickaël Camus

The advent of hybrid computing platforms consisting of quantum processing units integrated with conventional high-performance computing brings new opportunities for algorithm design. By strategically offloading select portions of the…

Quantum Machine Learning has the potential to improve traditional machine learning methods and overcome some of the main limitations imposed by the classical computing paradigm. However, the practical advantages of using quantum resources…

Quantum Physics · Physics 2023-03-21 Antonio Macaluso , Matthias Klusch , Stefano Lodi , Claudio Sartori

We review the recent quantum advantage experiments by IBM, D-Wave, and Google, focusing on cases where efficient classical simulations of the experiment were demonstrated or attempted using tensor network methods. We assess the strengths…

Quantum Physics · Physics 2026-03-27 Augustine Kshetrimayum , Saeed S. Jahromi , Sukhbinder Singh , Román Orús

The advent of quantum algorithms has initiated a discourse on the potential for quantum speedups for optimization problems. However, several factors still hinder a practical realization of the potential benefits. These include the lack of…

The quantum advantage threshold determines when a quantum processing unit (QPU) is more efficient with respect to classical computing hardware in terms of algorithmic complexity. The "green" quantum advantage threshold $-$ based on a…

Quantum Physics · Physics 2023-01-27 Daniel Jaschke , Simone Montangero

Quantum computing provides a new way for approaching problem solving, enabling efficient solutions for problems that are hard on classical computers. It is based on leveraging how quantum particles behave. With researchers around the world…

Quantum Physics · Physics 2021-09-29 Ahmed Shokry , Moustafa Youssef

Achieving high-performance computation on quantum systems presents a formidable challenge that necessitates bridging the capabilities between quantum hardware and classical computing resources. This study introduces an innovative…

Quantum Physics · Physics 2024-03-19 Kuan-Cheng Chen , Xiaoren Li , Xiaotian Xu , Yun-Yuan Wang , Chen-Yu Liu
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