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Large Vision-Language Models (VLMs) are increasingly being regarded as foundation models that can be instructed to solve diverse tasks by prompting, without task-specific training. We examine the seemingly obvious question: how to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Niccolo Avogaro , Thomas Frick , Mattia Rigotti , Andrea Bartezzaghi , Filip Janicki , Cristiano Malossi , Konrad Schindler , Roy Assaf

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

Few-shot Whole Slide Image (WSI) classification is severely hampered by overfitting. We argue that this is not merely a data-scarcity issue but a fundamentally geometric problem. Grounded in the manifold hypothesis, our analysis shows that…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Conghao Xiong , Zhengrui Guo , Zhe Xu , Yifei Zhang , Raymond Kai-Yu Tong , Si Yong Yeo , Hao Chen , Joseph J. Y. Sung , Irwin King

Pre-trained vision-language models (VLMs) are highly adaptable to various downstream tasks through few-shot learning, making prompt-based anomaly detection a promising approach. Traditional methods depend on human-crafted prompts that…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Pi-Wei Chen , Jerry Chun-Wei Lin , Jia Ji , Feng-Hao Yeh , Zih-Ching Chen , Chao-Chun Chen

While large visual models (LVM) demonstrated significant potential in image understanding, due to the application of large-scale pre-training, the Segment Anything Model (SAM) has also achieved great success in the field of image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Jiaqi Yang , Yaning Zhang , Jingxi Hu , Xiangjian He , Linlin Shen , Guoping Qiu

Video-and-language pre-training has shown promising improvements on various downstream tasks. Most previous methods capture cross-modal interactions with a transformer-based multimodal encoder, not fully addressing the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2021-12-24 Dongxu Li , Junnan Li , Hongdong Li , Juan Carlos Niebles , Steven C. H. Hoi

Few-shot segmentation aims at assigning a category label to each image pixel with few annotated samples. It is a challenging task since the dense prediction can only be achieved under the guidance of latent features defined by sparse…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Kai Zhu , Wei Zhai , Zheng-Jun Zha , Yang Cao

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

Vision-language models (VLMs) can learn high-quality representations from a large-scale training dataset of image-text pairs. Prompt learning is a popular approach to fine-tuning VLM to adapt them to downstream tasks. Despite the satisfying…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zhifang Zhang , Yuwei Niu , Xin Liu , Beibei Li

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Medical image analysis using deep learning is often challenged by limited labeled data and high annotation costs. Fine-tuning the entire network in label-limited scenarios can lead to overfitting and suboptimal performance. Recently, prompt…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Fan Bai , Ke Yan , Xiaoyu Bai , Xinyu Mao , Xiaoli Yin , Jingren Zhou , Yu Shi , Le Lu , Max Q. -H. Meng

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

Few-shot learning aims to train models that can be generalized to novel classes with only a few samples. Recently, a line of works are proposed to enhance few-shot learning with accessible semantic information from class names. However,…

Machine Learning · Computer Science 2023-07-11 Zihao Jiang , Yunkai Dang , Dong Pang , Huishuai Zhang , Weiran Huang

Image recognition has recently witnessed a paradigm shift, where vision-language models are now used to perform few-shot classification based on textual prompts. Among these, the CLIP model has shown remarkable capabilities for zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Lorenzo Agnolucci , Alberto Baldrati , Francesco Todino , Federico Becattini , Marco Bertini , Alberto Del Bimbo

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Vision-language (VL) Pre-training (VLP) has shown to well generalize VL models over a wide range of VL downstream tasks, especially for cross-modal retrieval. However, it hinges on a huge amount of image-text pairs, which requires tedious…

Information Retrieval · Computer Science 2023-07-20 Zixin Guo , Tzu-Jui Julius Wang , Selen Pehlivan , Abduljalil Radman , Jorma Laaksonen
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