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This paper presents RadOnc-GPT, a large language model specialized for radiation oncology through advanced tuning methods. RadOnc-GPT was finetuned on a large dataset of radiation oncology patient records from the Mayo Clinic in Arizona.…

In-basket message interactions play a crucial role in physician-patient communication, occurring during all phases (pre-, during, and post) of a patient's care journey. However, responding to these patients' inquiries has become a…

Managing scan protocols in Computed Tomography (CT), which includes adjusting acquisition parameters or configuring reconstructions, as well as selecting postprocessing tools in a patient-specific manner, is time-consuming and requires…

Artificial Intelligence · Computer Science 2025-09-25 Xingjian Kang , Linda Vorberg , Andreas Maier , Alexander Katzmann , Oliver Taubmann

This study introduces "RadCouncil," a multi-agent Large Language Model (LLM) framework designed to enhance the generation of impressions in radiology reports from the finding section. RadCouncil comprises three specialized agents: 1) a…

Computation and Language · Computer Science 2024-12-11 Fang Zeng , Zhiliang Lyu , Quanzheng Li , Xiang Li

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Evaluating generated radiology reports is crucial for the development of radiology AI, but existing metrics fail to reflect the task's clinical requirements. This study proposes a novel evaluation framework using large language models…

Computation and Language · Computer Science 2024-04-02 Zilong Wang , Xufang Luo , Xinyang Jiang , Dongsheng Li , Lili Qiu

Accurate estimation of cancer risk from longitudinal electronic health records (EHRs) could support earlier detection and improved care, but modeling such complex patient trajectories remains challenging. We present TrajOnco, a…

Artificial Intelligence · Computer Science 2026-04-14 Sihang Zeng , Young Won Kim , Wilson Lau , Ehsan Alipour , Ruth Etzioni , Meliha Yetisgen , Anand Oka

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

Radiology reports summarize key findings and differential diagnoses derived from medical imaging examinations. The extraction of differential diagnoses is crucial for downstream tasks, including patient management and treatment planning.…

Computation and Language · Computer Science 2024-10-15 Luoyao Chen , Revant Teotia , Antonio Verdone , Aidan Cardall , Lakshay Tyagi , Yiqiu Shen , Sumit Chopra

Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…

The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized…

Recent advancements in Large Language Models (LLMs) and related technologies such as Retrieval-Augmented Generation (RAG) and Diagram of Thought (DoT) have enabled the creation of autonomous intelligent systems capable of performing cluster…

Artificial Intelligence · Computer Science 2024-11-11 Honghao Shi , Longkai Cheng , Wenli Wu , Yuhang Wang , Xuan Liu , Shaokai Nie , Weixv Wang , Xuebin Min , Chunlei Men , Yonghua Lin

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Radiology report annotation is essential for clinical NLP, yet manual labeling is slow and costly. We present RadAnnotate, an LLM-based framework that studies retrieval-augmented synthetic reports and confidence-based selective automation…

Computation and Language · Computer Science 2026-03-18 Saisha Pradeep Shetty , Roger Eric Goldman , Vladimir Filkov

In radiology, Artificial Intelligence (AI) has significantly advanced report generation, but automatic evaluation of these AI-produced reports remains challenging. Current metrics, such as Conventional Natural Language Generation (NLG) and…

Computation and Language · Computer Science 2024-02-20 Qingqing Zhu , Xiuying Chen , Qiao Jin , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Xin Gao , Ronald M Summers , Zhiyong Lu

Automatic medical report generation has the potential to support clinical diagnosis, reduce the workload of radiologists, and demonstrate potential for enhancing diagnostic consistency. However, current evaluation metrics often fail to…

Computation and Language · Computer Science 2025-08-06 Zhenxuan Zhang , Kinhei Lee , Peiyuan Jing , Weihang Deng , Huichi Zhou , Zihao Jin , Jiahao Huang , Zhifan Gao , Dominic C Marshall , Yingying Fang , Guang Yang

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Cancer stage classification is important for making treatment and care management plans for oncology patients. Information on staging is often included in unstructured form in clinical, pathology, radiology and other free-text reports in…

Computation and Language · Computer Science 2024-09-04 Chia-Hsuan Chang , Mary M. Lucas , Grace Lu-Yao , Christopher C. Yang
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