Related papers: Load Transfer along Continuous Collagen Fibers Red…
The stochastic variations in the structural properties of thin fiber networks govern to a great extent their mechanical performance. To assess the influence of local structural variability on the local strain and mechanical response of the…
Fibrous networks such as collagen are common in physiological systems. One important function of these networks is to provide mechanical stability for cells and tissues. At physiological levels of connectivity, such networks would be…
In fibrous paper materials, an exposure to a variation in moisture content causes changes in the geometrical and mechanical properties. Such changes are strongly affected by the inter-fibre bonds, which are responsible for the transfer of…
Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has long been known that collagenous tissues exhibit a highly nonlinear stress-strain…
This paper investigates the effects of plasticity on the effective fracture toughness. A layered material is considered as a modelling system. An elastic-plastic phase-field model and a surfing boundary condition are used to study how the…
For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…
Cells can sense and respond to mechanical signals over relatively long distances across fibrous extracellular matrices. Here, we explore all of the key factors that influence long range force transmission in cell-populated collagen…
Cyclic loading is a common feature in poroelastic systems, the material response depending non-trivially on the exact form of boundary conditions, pore structure, and mechanical properties. The situation becomes more complex when…
Nanoscale molecular transport plays a crucial role in regulating mass diffusion and responsiveness in condensed matter systems. In soft porous crystals, in particular, adsorption of guest molecules induces host framework deformation and…
The possible transport of fibers by fluid flow in fractures is investigated experimentally in transparent models using flexible polyester thread (mean diameter $280 \mu\mathrm{m}$) and Newtonian and shear thinning fluids. In the case of…
Tissue engineering aims to grow artificial tissues \emph{in vitro} to replace those in the body that have been damaged through age, trauma or disease. A recent approach to engineer artificial cartilage involves seeding cells within a…
Disordered athermal biopolymer materials, such as collagen networks that constitute a major component in extracellular matrices and various connective tissues, are initially soft and compliant but stiffen dramatically under strain. Such…
The primary building block of the body is collagen, which is found in the extracellular matrix and in many stress-bearing tissues such as tendon and cartilage. It provides elasticity and support to cells and tissues while influencing…
In articular cartilage the orientation of collagen fibres is not uniform, varying mostly with the depth on the tissue. Besides, the biomechanical response of each layer of the articular cartilage differs from the neighbouring ones, evolving…
Many biological tissues feature a heterogeneous network of fibers whose tensile and bending rigidity contribute substantially to these tissues' elastic properties. Rigidity percolation has emerged as a important paradigm for relating these…
We study the influence of cell-level mechanical heterogeneity in epithelial tissues using a vertex-based model. Heterogeneity in single cell stiffness is introduced as a quenched random variable in the preferred shape index($p_0$) for each…
In this work, we developed an improved shear lag model to investigate the load transfer characteristics of three-phase nanocomposite which is reinforced with microscale fibers augmented with carbon nanotubes on their circumferential…
Statistical models are essential to get a better understanding of the role of disorder in brittle disordered solids. Fiber bundle models play a special role as a paradigm, with a very good balance of simplicity and non-trivial effects. We…
The present work deals with the behavior of fiber bundle model under heterogeneous loading condition. The model is explored both in the mean-field limit as well as with local stress concentration. In the mean field limit, the failure…
Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…