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Remarkable progress in 2D Vision-Language Models (VLMs) has spurred interest in extending them to 3D settings for tasks like 3D Question Answering, Dense Captioning, and Visual Grounding. Unlike 2D VLMs that typically process images through…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Haoyuan Li , Yanpeng Zhou , Yufei Gao , Tao Tang , Jianhua Han , Yujie Yuan , Dave Zhenyu Chen , Jiawang Bian , Hang Xu , Xiaodan Liang

Studying protein mutations within amino acid sequences holds tremendous significance in life sciences. Protein language models (PLMs) have demonstrated strong capabilities in broad biological applications. However, due to architectural…

Machine Learning · Computer Science 2024-10-31 Yizhen Luo , Zikun Nie , Massimo Hong , Suyuan Zhao , Hao Zhou , Zaiqing Nie

Graphs as a type of data structure have recently attracted significant attention. Representation learning of geometric graphs has achieved great success in many fields including molecular, social, and financial networks. It is natural to…

Machine Learning · Computer Science 2021-07-08 Tian Xia , Wei-Shinn Ku

Background: The inception of next generations sequencing technologies have exponentially increased the volume of biological sequence data. Protein sequences, being quoted as the `language of life', has been analyzed for a multitude of…

Quantitative Methods · Quantitative Biology 2020-12-08 Nabil Ibtehaz , S. M. Shakhawat Hossain Sourav , Md. Shamsuzzoha Bayzid , M. Sohel Rahman

Spoken language models (SLMs) that integrate speech with large language models (LMs) rely on modality adapters (MAs) to map the output of speech encoders to a representation that is understandable to the decoder LM. Yet we know very little…

Computation and Language · Computer Science 2025-10-20 Tolúlopé Ògúnrèmí , Christopher D. Manning , Dan Jurafsky , Karen Livescu

Effective protein representation learning is crucial for predicting protein functions. Traditional methods often pretrain protein language models on large, unlabeled amino acid sequences, followed by finetuning on labeled data. While…

Biomolecules · Quantitative Biology 2024-09-05 Jiangbin Zheng , Stan Z. Li

Predicting the fitness impact of mutations is central to protein engineering but constrained by limited assays relative to the size of sequence space. Protein language models (pLMs) trained with masked language modeling (MLM) exhibit strong…

Machine Learning · Computer Science 2026-04-14 Jigang Fan , Xiaoran Jiao , Shengdong Lin , Zhanming Liang , Weian Mao , Chenchen Jing , Hao Chen , Chunhua Shen

Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function. They thus open the possibility…

Biomolecules · Quantitative Biology 2024-12-30 Damiano Sgarbossa , Umberto Lupo , Anne-Florence Bitbol

Knowledge Representation Learning (KRL) is crucial for enabling applications of symbolic knowledge from Knowledge Graphs (KGs) to downstream tasks by projecting knowledge facts into vector spaces. Despite their effectiveness in modeling KG…

Computation and Language · Computer Science 2025-04-09 Xin Wang , Zirui Chen , Haofen Wang , Leong Hou U , Zhao Li , Wenbin Guo

Vision-Language Models (VLMs) are powerful tools for processing and understanding text and images. We study the processing of visual tokens in the language model component of LLaVA, a prominent VLM. Our approach focuses on analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Clement Neo , Luke Ong , Philip Torr , Mor Geva , David Krueger , Fazl Barez

The interpretation of multi-temporal remote sensing imagery is critical for monitoring Earth's dynamic processes-yet previous change detection methods, which produce binary or semantic masks, fall short of providing human-readable insights…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Chenyang Liu , Jiafan Zhang , Keyan Chen , Man Wang , Zhengxia Zou , Zhenwei Shi

Vision-Language Models (VLMs) leverage aligned visual encoders to transform images into visual tokens, allowing them to be processed similarly to text by the backbone large language model (LLM). This unified input paradigm enables VLMs to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Bangzheng Li , Fei Wang , Wenxuan Zhou , Nan Xu , Ben Zhou , Sheng Zhang , Hoifung Poon , Muhao Chen

Pretrained models have produced great success in both Computer Vision (CV) and Natural Language Processing (NLP). This progress leads to learning joint representations of vision and language pretraining by feeding visual and linguistic…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Siqu Long , Feiqi Cao , Soyeon Caren Han , Haiqin Yang

The increasing number of protein sequences decoded from genomes is opening up new avenues of research on linking protein sequence to function with transformer neural networks. Recent research has shown that the number of known protein…

Machine Learning · Computer Science 2022-06-23 Anowarul Kabir , Amarda Shehu

Multilingual language models (LMs) organize representations for typologically and orthographically diverse languages into a shared parameter space, yet the nature of this internal organization remains elusive. In this work, we investigate…

Computation and Language · Computer Science 2026-04-22 Aastha A K Verma , Anwoy Chatterjee , Mehak Gupta , Tanmoy Chakraborty

Multilingual Large Language Models (LLMs) can process many languages, yet how they internally represent this diversity remains unclear. Do they form shared multilingual representations with language-specific decoding, and if so, why does…

Computation and Language · Computer Science 2026-02-10 Abir Harrasse , Florent Draye , Punya Syon Pandey , Zhijing Jin , Bernhard Schölkopf

This paper reveals that large language models (LLMs), despite being trained solely on textual data, are surprisingly strong encoders for purely visual tasks in the absence of language. Even more intriguingly, this can be achieved by a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Ziqi Pang , Ziyang Xie , Yunze Man , Yu-Xiong Wang

We study how large language models (LLMs) ``think'' through their representation space. We propose a novel geometric framework that models an LLM's reasoning as flows -- embedding trajectories evolving where logic goes. We disentangle…

Artificial Intelligence · Computer Science 2026-03-05 Yufa Zhou , Yixiao Wang , Xunjian Yin , Shuyan Zhou , Anru R. Zhang

Dense retrieval models usually adopt vectors from the last hidden layer of the document encoder to represent a document, which is in contrast to the fact that representations in different layers of a pre-trained language model usually…

Information Retrieval · Computer Science 2025-09-30 Zhongbin Xie , Thomas Lukasiewicz

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

Biological Physics · Physics 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi
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