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By composing graphical models with deep learning architectures, we learn generative models with the strengths of both frameworks. The structured variational autoencoder (SVAE) inherits structure and interpretability from graphical models,…

Machine Learning · Computer Science 2023-11-15 Harry Bendekgey , Gabriel Hope , Erik B. Sudderth

The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

Recently, autoencoders (AEs) have gained interest for creating parametric and invertible projections of multidimensional data. Parametric projections make it possible to embed new, unseen samples without recalculating the entire projection,…

Machine Learning · Computer Science 2025-11-26 Frederik L. Dennig , Daniel A. Keim

Layout design with complex constraints is a challenging problem to solve due to the non-uniqueness of the solution and the difficulties in incorporating the constraints into the conventional optimization-based methods. In this paper, we…

Signal Processing · Electrical Eng. & Systems 2018-06-11 Yujie Zhang , Wenjing Ye

As a widely recognized approach to deep generative modeling, Variational Auto-Encoders (VAEs) still face challenges with the quality of generated images, often presenting noticeable blurriness. This issue stems from the unrealistic…

Machine Learning · Computer Science 2023-05-22 Georgios Batzolis , Jan Stanczuk , Carola-Bibiane Schönlieb

Given the complex geometry of white matter streamlines, Autoencoders have been proposed as a dimension-reduction tool to simplify the analysis streamlines in a low-dimensional latent spaces. However, despite these recent successes, the…

Machine Learning · Statistics 2023-11-21 Andrew Lizarraga , Brandon Taraku , Edouardo Honig , Ying Nian Wu , Shantanu H. Joshi

Variational Auto-encoders (VAEs) have been very successful as methods for forming compressed latent representations of complex, often high-dimensional, data. In this paper, we derive an alternative variational lower bound from the one…

Machine Learning · Computer Science 2019-03-20 Shuyu Lin , Ronald Clark , Robert Birke , Niki Trigoni , Stephen Roberts

We extend variational autoencoders (VAEs) to collaborative filtering for implicit feedback. This non-linear probabilistic model enables us to go beyond the limited modeling capacity of linear factor models which still largely dominate…

Machine Learning · Statistics 2018-02-19 Dawen Liang , Rahul G. Krishnan , Matthew D. Hoffman , Tony Jebara

Variational Autoencoders (VAEs) typically rely on a probabilistic decoder with a predefined likelihood, most commonly an isotropic Gaussian, to model the data conditional on latent variables. While convenient for optimization, this choice…

Machine Learning · Statistics 2025-04-29 Chen Xu , Qiang Wang , Lijun Sun

Synthetic data generation is of great interest in diverse applications, such as for privacy protection. Deep generative models, such as variational autoencoders (VAEs), are a popular approach for creating such synthetic datasets from…

Machine Learning · Statistics 2021-05-17 Kiana Farhadyar , Federico Bonofiglio , Daniela Zoeller , Harald Binder

Deep Learning based methods have emerged as the indisputable leaders for virtually all image restoration tasks. Especially in the domain of microscopy images, various content-aware image restoration (CARE) approaches are now used to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mangal Prakash , Alexander Krull , Florian Jug

We present a novel method for constructing Variational Autoencoder (VAE). Instead of using pixel-by-pixel loss, we enforce deep feature consistency between the input and the output of a VAE, which ensures the VAE's output to preserve the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Xianxu Hou , Linlin Shen , Ke Sun , Guoping Qiu

Latent generative models have emerged as a leading approach for high-quality image synthesis. These models rely on an autoencoder to compress images into a latent space, followed by a generative model to learn the latent distribution. We…

Machine Learning · Computer Science 2025-08-05 Theodoros Kouzelis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

We consider the problem of learning Variational Autoencoders (VAEs), i.e., a type of deep generative model, from data with missing values. Such data is omnipresent in real-world applications of machine learning because complete data is…

Machine Learning · Computer Science 2023-10-26 Timur Sudak , Sebastian Tschiatschek

In just three years, Variational Autoencoders (VAEs) have emerged as one of the most popular approaches to unsupervised learning of complicated distributions. VAEs are appealing because they are built on top of standard function…

Machine Learning · Statistics 2021-01-05 Carl Doersch

In data-driven drug discovery, designing molecular descriptors is a very important task. Deep generative models such as variational autoencoders (VAEs) offer a potential solution by designing descriptors as probabilistic latent vectors…

Machine Learning · Computer Science 2023-08-23 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

Variational autoencoders (VAEs) are one class of generative probabilistic latent-variable models designed for inference based on known data. They balance reconstruction and regularizer terms. A variational approximation produces an evidence…

Machine Learning · Statistics 2023-12-13 Robert I. Cukier

Learning a disentangled, interpretable, and structured latent representation in 3D generative models of faces and bodies is still an open problem. The problem is particularly acute when control over identity features is required. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Simone Foti , Bongjin Koo , Danail Stoyanov , Matthew J. Clarkson

Recent successes in image generation, model-based reinforcement learning, and text-to-image generation have demonstrated the empirical advantages of discrete latent representations, although the reasons behind their benefits remain unclear.…

Machine Learning · Computer Science 2023-07-27 David Friede , Christian Reimers , Heiner Stuckenschmidt , Mathias Niepert
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