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In this article, we present a method for computing accurate and scalable nuclear forces within the phaseless auxiliary-field quantum Monte Carlo (AFQMC) framework. Our approach leverages automatic differentiation of the energy functional to…

Chemical Physics · Physics 2026-02-16 Jo S. Kurian , Ankit Mahajan , Sandeep Sharma

Nuclear Magnetic Resonance (NMR) spectroscopy is the cornerstone of small-molecule structure elucidation. While deep learning has demonstrated significant potential in automating structure elucidation and spectral simulation, current…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Zheng Fang , Chen Yang , Hai-tao Yu , Haoming Luo , Haitao He , Jiaqing Xie , Zhuo Yang , Jun Xia

Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

Neutrino-nuclear responses in the form of squares of nuclear matrix elements,NMEs, are crucial for studies of neutrino-induced processes in nuclei. In this work we investigate magnetic hexadecapole (M4) NMEs in medium-heavy nuclei. The…

Nuclear Theory · Physics 2016-04-18 Lotta Jokiniemi , Jouni Suhonen , Hiroyasu Ejiri

Quantum sensors have recently achieved to detect the magnetic moment of few or single nuclear spins and measure their magnetic resonance (NMR) signal. However, the spectral resolution, a key feature of NMR, has been limited by relaxation of…

Quantum reinforcement learning (QRL) promises compact function approximators with access to vast Hilbert spaces, but its practical progress is slowed by NISQ-era constraints such as limited qubits and noise accumulation. We introduce a…

Quantum Physics · Physics 2025-09-03 Junghoon Justin Park , Huan-Hsin Tseng , Shinjae Yoo , Samuel Yen-Chi Chen , Jiook Cha

A novel estimation approach for a general class of semi-parametric multivariate time series models is introduced where the conditional mean is modeled through parametric functions. The focus of the estimation is the conditional mean…

Methodology · Statistics 2025-07-21 Mirko Armillotta

We propose a novel MRI (Magnetic Resonance Imaging) technique based quantum bit (qubit) generation with water proton NMR (1H-NMR), distinct from previously proposed NMR chemical shift or spectroscopic techniques based qubit generation. We…

Quantum Physics · Physics 2025-05-22 Z. H. Cho , J. H. Han , D. H. Suk , H. J. Jeung , S. Z. Lee , Y. B. Kim , S. H. Paek , H. G. Lee

This work studies the feasibility of applying quantum kernel methods to a real consumer classification task in the NISQ regime. We present a hybrid pipeline that combines a quantum-kernel Support Vector Machine (Q-SVM) with a quantum…

Quantum Physics · Physics 2026-03-04 Laura Sáez-Ortuño , Santiago Forgas-Coll , Massimiliano Ferrara

Quantum kernel methods (QKMs) have emerged as a prominent framework for supervised quantum machine learning. Unlike variational quantum algorithms, which rely on gradient-based optimisation and may suffer from issues such as barren…

Quantum Physics · Physics 2026-04-10 John Tanner , Chon-Fai Kam , Jingbo Wang

Quantum Computing (QC) offers outstanding potential for molecular characterization and drug discovery, particularly in solving complex properties like the Ground State Energy (GSE) of biomolecules. However, QC faces challenges due to…

Chemical Physics · Physics 2024-12-17 Laia Coronas Sala , Parfait Atchade-Adelemou

Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful and widely used tools for molecular structure elucidation in organic chemistry. However, the interpretation of NMR spectra to determine unknown molecular structures…

Chemical Physics · Physics 2025-09-03 Yongqi Jin , Jun-Jie Wang , Fanjie Xu , Xiaohong Ji , Zhifeng Gao , Linfeng Zhang , Guolin Ke , Rong Zhu , Weinan E

Hybrid quantum mechanical-molecular mechanical (QM/MM) simulations are widely used in enzyme simulation. Over ten convergence studies of QM/MM methods have revealed over the past several years that key energetic and structural properties…

Chemical Physics · Physics 2017-01-11 Maria Karelina , Heather J. Kulik

Quantum policy evaluation (QPE) is a reinforcement learning (RL) algorithm which is quadratically more efficient than an analogous classical Monte Carlo estimation. It makes use of a direct quantum mechanical realization of a finite Markov…

In scientific computing, the formulation of numerical discretisations of partial differential equations (PDEs) as untrained convolutional layers within Convolutional Neural Networks (CNNs), referred to by some as Neural Physics, has…

In relation to recent experimental data [1], we develop a theory framework for demonstrating the feasibility of detecting sharp Nuclear Magnetic Resonance (NMR) oscillations in a real time ESR data. The procedure is to follow real time…

Mesoscale and Nanoscale Physics · Physics 2025-09-04 Baruch Horovitz , Alexander Shnirman

We propose the use of the ``spin-opstring", derived from Stochastic Series Expansion Quantum Monte Carlo (QMC) simulations as machine learning (ML) input data. It offers a compact, memory-efficient representation of QMC simulation cells,…

Strongly Correlated Electrons · Physics 2025-11-05 Amrita Ghosh , Mugdha Sarkar , Ying-Jer Kao , Pochung Chen

In the accompanying paper of arXiv:2505.00697, we have presented a generalized scheme of adaptive quantum gradient estimation (QGE) algorithm, and further proposed two practical variants which not only achieve doubly quantum enhancement in…

Quantum Physics · Physics 2025-05-05 Yuki Koizumi , Kaito Wada , Wataru Mizukami , Nobuyuki Yoshioka

Nuclear magnetic resonance imaging (MRI) at the atomic scale offers exciting prospects for determining the structure and function of individual molecules and proteins. Quantum defects in diamond have recently emerged as a promising platform…

Quantum Physics · Physics 2022-04-06 K. S. Cujia , K. Herb , J. Zopes , J. M. Abendroth , C. L. Degen

Much new solid state technology for single-photon sources, detectors, photovoltaics and quantum computation relies on the fabrication of strained semiconductor nanostructures. Successful development of these devices depends strongly on…