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Hallucination remains a critical challenge in large language models (LLMs), hindering the development of reliable multimodal LLMs (MLLMs). Existing solutions often rely on human intervention or underutilize the agent's ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Zhongyu Yang , Yingfang Yuan , Xuanming Jiang , Baoyi An , Wei Pang

Large vision-language models (VLMs) demonstrate strong performance in medical image understanding, but frequently generate clinically plausible yet incorrect statements, raising significant safety concerns. Existing medical hallucination…

Recent advances in multimodal large language models (MLLMs) mark a shift from non-thinking models to post-trained reasoning models capable of solving complex problems through thinking. However, whether such thinking mitigates hallucinations…

Computation and Language · Computer Science 2026-02-02 Zhidian Huang , Zijun Yao , Ji Qi , Shangqing Tu , Junxian Ma , Jinxin Liu , Weichuan Liu , Xiaoyin Che , Lei Hou , Juanzi Li

Large Language Models (LLMs) have achieved remarkable reliability and advanced capabilities through extended test-time reasoning. However, extending these capabilities to Multi-modal Large Language Models (MLLMs) remains a significant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yuhao Dong , Zuyan Liu , Shulin Tian , Yongming Rao , Ziwei Liu

Multimodal Large Language Models (MLLMs) have recently demonstrated impressive capabilities in multimodal understanding, reasoning, and interaction. However, existing MLLMs prevalently suffer from serious hallucination problems, generating…

Computation and Language · Computer Science 2024-03-11 Tianyu Yu , Yuan Yao , Haoye Zhang , Taiwen He , Yifeng Han , Ganqu Cui , Jinyi Hu , Zhiyuan Liu , Hai-Tao Zheng , Maosong Sun , Tat-Seng Chua

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Multi-modal Large Language Models (MLLMs) are increasingly prominent in the field of artificial intelligence. These models not only excel in traditional vision-language tasks but also demonstrate impressive performance in contemporary…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Xiaotian Han , Quanzeng You , Yongfei Liu , Wentao Chen , Huangjie Zheng , Khalil Mrini , Xudong Lin , Yiqi Wang , Bohan Zhai , Jianbo Yuan , Heng Wang , Hongxia Yang

Medical Large Language Models (MLLMs) have demonstrated potential in healthcare applications, yet their propensity for hallucinations -- generating medically implausible or inaccurate information -- presents substantial risks to patient…

Computation and Language · Computer Science 2025-04-01 Kaiwen Zuo , Yirui Jiang

The advent of large language models (LLMs) has facilitated the development of natural language text generation. It also poses unprecedented challenges, with content hallucination emerging as a significant concern. Existing solutions often…

Computation and Language · Computer Science 2024-06-06 Xiaoxi Sun , Jinpeng Li , Yan Zhong , Dongyan Zhao , Rui Yan

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent…

Machine Learning · Computer Science 2026-01-27 Peng Xia , Jinglu Wang , Yibo Peng , Kaide Zeng , Zihan Dong , Xian Wu , Xiangru Tang , Hongtu Zhu , Yun Li , Linjun Zhang , Shujie Liu , Yan Lu , Huaxiu Yao

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

Large Language Models (LLMs) show promise in medicine but are prone to factual and logical errors, which is unacceptable in this high-stakes field. To address this, we introduce the "Haibu Mathematical-Medical Intelligent Agent" (MMIA), an…

Artificial Intelligence · Computer Science 2025-10-10 Yilun Zhang , Dexing Kong

Large Vision Language Models (LVLMs) are becoming increasingly important in the medical domain, yet Medical LVLMs (Med-LVLMs) frequently generate hallucinations due to limited expertise and the complexity of medical applications. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Aofei Chang , Le Huang , Parminder Bhatia , Taha Kass-Hout , Fenglong Ma , Cao Xiao

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

Artificial Intelligence · Computer Science 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Long-form mental health assessments pose unique challenges for large language models (LLMs), which often exhibit hallucinations or inconsistent reasoning when handling extended, domain-specific contexts. We introduce Stacked Multi-Model…

Computation and Language · Computer Science 2025-09-22 Jinwen Tang , Qiming Guo , Wenbo Sun , Yi Shang

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Large Language Models (LLMs) have demonstrated advanced capabilities but often suffer from factual inaccuracies (hallucinations) and systematic biases. These issues, sometimes amplified in specific architectures like Mixture-of-Experts…

Computation and Language · Computer Science 2026-04-28 Shuai Wu , Xue Li , Yanna Feng , Yufang Li , Zhijun Wang , Ran Wang

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu