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Current AI agent frameworks commit early to a single interaction protocol, a fixed tool integration strategy, and static user models, limiting their deployment across diverse interaction paradigms. To address these constraints, we introduce…

Artificial Intelligence · Computer Science 2026-03-25 Alfred Shen , Aaron Shen

The development of autonomous tool-use agents for complex, long-horizon tasks in collaboration with human users has become the frontier of agentic research. During multi-turn Human-AI interactions, the dynamic and uncertain nature of user…

Artificial Intelligence · Computer Science 2026-04-10 Prince Zizhuang Wang , Shuli Jiang

Remarkable advancements in modern generative foundation models have enabled the development of sophisticated and highly capable autonomous agents that can observe their environment, invoke tools, and communicate with other agents to solve…

Human-Computer Interaction · Computer Science 2024-12-17 Gagan Bansal , Jennifer Wortman Vaughan , Saleema Amershi , Eric Horvitz , Adam Fourney , Hussein Mozannar , Victor Dibia , Daniel S. Weld

Cancer survivors face elevated rates of depression, anxiety, and general emotional distress, yet the precise moments they most need support are often the moments when self-report is sparse, a phenomenon we term the diary paradox. Passive…

Human-Computer Interaction · Computer Science 2026-05-19 Zhiyuan Wang , Ariful Islam , Indrajeet Ghosh , Xinyu Chen , Katharine E. Daniel , Subigya Nepal , Philip Chow , Laura E. Barnes

United States healthcare systems are struggling to meet the growing demand for neurological care, particularly in Alzheimer's disease and related dementias (ADRD). Generative AI built on language models (LLMs) now enables agentic AI systems…

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

On-device agents on smartphones increasingly require continuously evolving memory to support personalized, context-aware, and long-term behaviors. To meet both privacy and responsiveness demands, user data is embedded as vectors and stored…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-25 Xinkui Zhao , Qingyu Ma , Yifan Zhang , Hengxuan Lou , Guanjie Cheng , Shuiguang Deng , Jianwei Yin

Objective: This paper introduces a patient simulator for scalable, automated evaluation of healthcare conversational agents, generating realistic, controllable interactions that systematically vary across medical, linguistic, and behavioral…

With the rise of generative AI, industry interest in software agents is growing. Given the stochastic nature of generative AI-based agents, their effective and safe deployment in organizations requires robust governance, which can be…

Software Engineering · Computer Science 2025-07-04 Hoang Vu , Nataliia Klievtsova , Henrik Leopold , Stefanie Rinderle-Ma , Timotheus Kampik

AI Agents are changing the way work gets done, both in consumer and enterprise domains. However, the design patterns and architectures to build highly capable agents or multi-agent systems are still developing, and the understanding of the…

Artificial Intelligence · Computer Science 2024-07-19 Tamer Abuelsaad , Deepak Akkil , Prasenjit Dey , Ashish Jagmohan , Aditya Vempaty , Ravi Kokku

Integrated sensing and communication (ISAC) has emerged as a key development direction in the sixth-generation (6G) era, which provides essential support for the collaborative sensing and communication of future intelligent networks.…

Artificial Intelligence · Computer Science 2025-12-18 Wenwen Xie , Geng Sun , Ruichen Zhang , Xuejie Liu , Yinqiu Liu , Jiacheng Wang , Dusit Niyato , Ping Zhang

Alzheimer's disease (AD) presents a complex, multifaceted challenge to patients, caregivers, and the healthcare system, necessitating integrated and dynamic support solutions. While artificial intelligence (AI) offers promising avenues for…

Multiagent Systems · Computer Science 2025-10-13 Adib Bazgir , Amir Habibdoust , Xing Song , Yuwen Zhang

The automation of scientific research through large language models (LLMs) presents significant opportunities but faces critical challenges in knowledge synthesis and quality assurance. We introduce Feedback-Refined Agent Methodology…

Computation and Language · Computer Science 2025-11-18 Chengzhang Yu , Yiming Zhang , Zhixin Liu , Zenghui Ding , Yining Sun , Zhanpeng Jin

Multi-Agent Systems (MAS) powered by Large Language Models (LLMs) are emerging as a powerful paradigm for solving complex, multifaceted problems. However, the potential of these systems is often constrained by the prevalent plan-and-execute…

Artificial Intelligence · Computer Science 2025-07-18 Yexuan Shi , Mingyu Wang , Yunxiang Cao , Hongjie Lai , Junjian Lan , Xin Han , Yu Wang , Jie Geng , Zhenan Li , Zihao Xia , Xiang Chen , Chen Li , Jian Xu , Wenbo Duan , Yuanshuo Zhu

Future sixth-generation (6G) mobile networks are envisioned to be equipped with a diverse set of powerful, yet highly specialized, optimization experts. Such a promising vision is concurrently expected to give rise to the need for scalable…

Machine Learning · Computer Science 2026-05-06 Robert-Jeron Reifert , Alaa Alameer Ahmad , Hayssam Dahrouj , Aydin Sezgin

We examined the mechanisms underlying productivity and performance gains from AI agents using a large-scale experiment on Pairit, a platform we developed to study human-AI collaboration. We randomly assigned 2,234 participants to…

Computers and Society · Computer Science 2026-02-06 Harang Ju , Sinan Aral

In healthcare, the role of AI is continually evolving, and understanding the challenges its introduction poses on relationships between healthcare providers and patients will require a regulatory and behavioral approach that can provide a…

Computers and Society · Computer Science 2023-10-17 Chinasa T. Okolo , Michelle González Amador

Navigating healthcare systems can be complex and overwhelming, creating barriers for patients seeking timely and appropriate medical attention. In this paper, we introduce C-PATH (Conversational Patient Assistance and Triage in Healthcare),…

Computation and Language · Computer Science 2025-06-10 Qi Shi , Qiwei Han , Cláudia Soares

Mass casualty incidents (MCIs) overwhelm healthcare systems and demand rapid, accurate patient-hospital allocation decisions under extreme pressure. Here, we developed and validated a deep reinforcement learning-based decision-support AI…

Machine Learning · Computer Science 2025-09-11 Zhaoxun "Lorenz" Liu , Wagner H. Souza , Jay Han , Amin Madani

In this paper, we describe the iterative participatory design of SOPHIE, an online virtual patient for feedback-based practice of sensitive patient-physician conversations, and discuss an initial qualitative evaluation of the system by…

Human-Computer Interaction · Computer Science 2020-09-24 Mohammad Rafayet Ali , Taylan Sen , Benjamin Kane , Shagun Bose , Thomas M Carroll , Ronald Epstein , Lenhart Schubert , Ehsan Hoque