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We apply the DiffC algorithm (Theis et al. 2022) to Stable Diffusion 1.5, 2.1, XL, and Flux-dev, and demonstrate that these pretrained models are remarkably capable lossy image compressors. A principled algorithm for lossy compression using…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Jeremy Vonderfecht , Feng Liu

Deep generative models have achieved tremendous success in structure-based drug design in recent years, especially for generating 3D ligand molecules that bind to specific protein pocket. Notably, diffusion models have transformed ligand…

Machine Learning · Computer Science 2024-12-03 Daiheng Zhang , Chengyue Gong , Qiang Liu

While diffusion models have set a new benchmark for quality in Low-Dose Computed Tomography (LDCT) denoising, their clinical adoption is critically hindered by extreme computational costs, with inference times often exceeding thousands of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Tangtangfang Fang , Jingxi Hu , Xiangjian He , Jiaqi Yang

We propose in this paper an analytically new construct of a diffusion model whose drift and diffusion parameters yield an exponentially time-decaying Signal to Noise Ratio in the forward process. In reverse, the construct cleverly carries…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Tanmay Asthana , Yufang Bao , Hamid Krim

Diffusion priors have been used for blind face restoration (BFR) by fine-tuning diffusion models (DMs) on restoration datasets to recover low-quality images. However, the naive application of DMs presents several key limitations. (i) The…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Senmao Li , Kai Wang , Joost van de Weijer , Fahad Shahbaz Khan , Chun-Le Guo , Shiqi Yang , Yaxing Wang , Jian Yang , Ming-Ming Cheng

Purpose: To develop a cardiac T1 mapping method for free-breathing 3D T1 mapping of the whole heart at 3T with transmit B1 (B1+) correction Methods: A free-breathing, ECG-gated inversion recovery sequence with spoiled gradient-echo readout…

Medical Physics · Physics 2021-11-16 Paul Kyu Han , Thibault Marin , Yanis Djebra , Vanessa Landes , Yue Zhuo , Georges El Fakhri , Chao Ma

Purpose: To accelerate radially sampled diffusion weighted spin-echo (Rad-DW-SE) acquisition method for generating high quality apparent diffusion coefficient (ADC) maps. Methods: A deep learning method was developed to generate accurate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Yuemeng Li , Miguel Romanello Joaquim , Stephen Pickup , Hee Kwon Song , Rong Zhou , Yong Fan

Multiparametric MRI is increasingly recommended as a first-line noninvasive approach to detect and localize prostate cancer, requiring at minimum diffusion-weighted (DWI) and T2-weighted (T2w) MR sequences. Early machine learning attempts…

Accurate segmentation of brain tumors in MRI scans is critical for clinical diagnosis and treatment planning. We propose a semi-supervised, two-stage framework that extends the ReCoSeg approach to the larger and more heterogeneous BraTS…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

Multi-contrast MRI protocols increase the level of morphological information available for diagnosis. Yet, the number and quality of contrasts is limited in practice by various factors including scan time and patient motion. Synthesis of…

Image and Video Processing · Electrical Eng. & Systems 2019-09-26 Mahmut Yurt , Salman Ul Hassan Dar , Aykut Erdem , Erkut Erdem , Tolga Çukur

Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Jiaxu Zheng , Meiman He , Xuhui Tang , Xiong Wang , Tuoyu Cao , Tianyi Zeng , Lichi Zhang , Chenyu You

The diffusion model has recently emerged as a potent approach in computer vision, demonstrating remarkable performances in the field of generative artificial intelligence. Capable of producing high-quality synthetic images, diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Abdullah , Tao Huang , Ickjai Lee , Euijoon Ahn

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

We propose continuous adversarial flow models, a type of continuous-time flow model trained with an adversarial objective. Unlike flow matching, which uses a fixed mean-squared-error criterion, our approach introduces a learned…

Machine Learning · Computer Science 2026-04-14 Shanchuan Lin , Ceyuan Yang , Zhijie Lin , Hao Chen , Haoqi Fan

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Text-to-image (T2I) diffusion models lack an efficient mechanism for early quality assessment, leading to costly trial-and-error in multi-generation scenarios such as prompt iteration, agent-based generation, and flow-grpo. We reveal a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Benlei Cui , Bukun Huang , Zhizeng Ye , Xuemei Dong , Tuo Chen , Hui Xue , Dingkang Yang , Longtao Huang , Jingqun Tang , Haiwen Hong

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth…

Contrast-enhanced imaging is central to oncologic diagnosis, but contrast agents can be contraindicated for many of the patients who need them most. Synthesizing contrast scans from non-contrast inputs is the natural response. Two obstacles…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Yifan Chen , Fei Yin , Hao Chen , Jia Wu , Chao Li

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mohammad Jafari Vayeghan , Niloufar Delfan , Mehdi Tale Masouleh , Mansour Parvaresh Rizi , Behzad Moshiri
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