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Over the past decade, generative models have demonstrated success in enhancing fundus images. However, the evaluation of these models remains a challenge. A benchmark for fundus image enhancement is needed for three main reasons:(1)…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Zhipeng Wang , Shao Tang , Oana Dumitrascu , Yalin Wang

Diabetic Retinopathy (DR) is a leading cause of blindness in working age adults. DR lesions can be challenging to identify in fundus images, and automatic DR detection systems can offer strong clinical value. Of the publicly available…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Qiqi Xiao , Jiaxu Zou , Muqiao Yang , Alex Gaudio , Kris Kitani , Asim Smailagic , Pedro Costa , Min Xu

In this project, we developed a deep learning system applied to human retina images for medical diagnostic decision support. The retina images were provided by EyePACS. These images were used in the framework of a Kaggle contest, whose…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Maria Camila Alvarez Trivino , Jeremie Despraz , Jesus Alfonso Lopez Sotelo , Carlos Andres Pena

Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Artem Sevastopolsky

Retinal imaging is fast, non-invasive, and widely available, offering quantifiable structural and vascular signals for ophthalmic and systemic health assessment. This accessibility creates an opportunity to study how quantitative retinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Zhonghua Wang , Lie Ju , Sijia Li , Wei Feng , Sijin Zhou , Ming Hu , Jianhao Xiong , Xiaoying Tang , Yifan Peng , Mingquan Lin , Yaodong Ding , Yong Zeng , Wenbin Wei , Li Dong , Zongyuan Ge

Diabetic Retinopathy (DR), a vision-threatening complication of Dia-betes Mellitus (DM), is a major global concern, particularly in India, which has one of the highest diabetic populations. Prolonged hyperglycemia damages reti-nal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Arpan Maity , Aviroop Pal , MD. Samiul Islam , Tamal Ghosh

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Diabetic retinopathy refers to the pathology of the retina induced by diabetes and is one of the leading causes of preventable blindness in the world. Early detection of diabetic retinopathy is critical to avoid vision problem through…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Malik A. Manan , Tariq M. Khan , Ahsan Saadat , Muhammad Arsalan , Syed S. Naqvi

The prevalence of diabetic retinopathy (DR) has reached 34.6% worldwide and is a major cause of blindness among middle-aged diabetic patients. Regular DR screening using fundus photography helps detect its complications and prevent its…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Fahman Saeed , Muhammad Hussain , Hatim A Aboalsamh , Fadwa Al Adel , Adi Mohammed Al Owaifeer

Diabetic retinopathy screening traditionally relies on fundus photography, requiring specialized equipment and expertise often unavailable in primary care and resource limited settings. We developed and validated a deep learning (DL) system…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Hasaan Maqsood , Saif Ur Rehman Khan , Sebastian Vollmer , Andreas Dengel , Muhammad Nabeel Asim

Assessing the degree of disease severity in biomedical images is a task similar to standard classification but constrained by an underlying structure in the label space. Such a structure reflects the monotonic relationship between different…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Adrian Galdran , José Dolz , Hadi Chakor , Hervé Lombaert , Ismail Ben Ayed

Diabetic retinopathy (DR) is a leading cause of vision impairment worldwide, and automated grading systems play a crucial role in large-scale screening programs. However, deep learning models often exhibit degraded performance when deployed…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Afshan Hashmi

Diabetic Retinopathy (DR) is a leading cause of vision loss in working-age individuals. Early detection of DR can reduce the risk of vision loss by up to 95%, but a shortage of retinologists and challenges in timely examination complicate…

Deep learning is currently the state-of-the-art for automated detection of referable diabetic retinopathy (DR) from color fundus photographs (CFP). While the general interest is put on improving results through methodological innovations,…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tomás Castilla , Marcela S. Martínez , Mercedes Leguía , Ignacio Larrabide , José Ignacio Orlando

In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Yifan Peng , Shazia Dharssi , Qingyu Chen , Tiarnan D. Keenan , Elvira Agrón , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

The segmentation of retinal vessels is of significance for doctors to diagnose the fundus diseases. However, existing methods have various problems in the segmentation of the retinal vessels, such as insufficient segmentation of retinal…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Yun Jiang , Ning Tan

The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…

Artificial Intelligence · Computer Science 2024-11-20 Syed Mohd Faisal Malik , Md Tabrez Nafis , Mohd Abdul Ahad , Safdar Tanweer

Diabetic Retinopathy (DR) is a common complication of diabetes and a leading cause of blindness worldwide. Early and accurate grading of its severity is crucial for disease management. Although deep learning has shown great potential for…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Haoxuan Che , Yuhan Cheng , Haibo Jin , Hao Chen