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Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…
Large Language Models (LLMs) are transforming healthcare through the development of LLM-based agents that can understand, reason about, and assist with medical tasks. This survey provides a comprehensive review of LLM-based agents in…
The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…
Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…
The rise of Large Reasoning Models (LRMs) signifies a paradigm shift toward advanced computational reasoning. Yet, this progress disrupts traditional agent frameworks, traditionally anchored by execution-oriented Large Language Models…
Document Visual Question Answering (DocVQA) remains challenging for existing Vision-Language Models (VLMs), especially under complex reasoning and multi-step workflows. Current approaches struggle to decompose intricate questions into…
Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…
As an agent-level reasoning and coordination paradigm, Multi-Agent Debate (MAD) orchestrates multiple agents through structured debate to improve answer quality and support complex reasoning. However, existing research on MAD suffers from…
Medical diagnosis using Large Multimodal Models (LMMs) has gained increasing attention due to capability of these models in providing precise diagnoses. These models generally combine medical questions with visual inputs to generate…
Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…
Large Language Models (LLMs) are playing an increasingly important role in physics research by assisting with symbolic manipulation, numerical computation, and scientific reasoning. However, ensuring the reliability, transparency, and…
Remarkable performance of large language models (LLMs) in a variety of tasks brings forth many opportunities as well as challenges of utilizing them in production settings. Towards practical adoption of LLMs, multi-agent systems hold great…
The Mental Health Question Answer (MHQA) task requires the seeker and supporter to complete the support process in one-turn dialogue. Given the richness of help-seeker posts, supporters must thoroughly understand the content and provide…
Large language model (LLM)-based multi-agent systems have demonstrated impressive capabilities in handling complex tasks. However, the complexity of agentic behaviors makes these systems difficult to understand. When failures occur,…
Multi-document Multi-entity Question Answering inherently demands models to track implicit logic between multiple entities across scattered documents. However, existing Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG)…
Large Language Models (LLMs) demonstrate strong generalization and reasoning abilities, making them well-suited for complex decision-making tasks such as medical consultation (MC). However, existing LLM-based methods often fail to capture…
Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same…
Large language models (LLMs) face persistent challenges when handling long-context tasks, most notably the lost in the middle issue, where information located in the middle of a long input tends to be underutilized. Some existing methods…
Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…
Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…