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Pneumonia is a lung infection that causes 15% of childhood mortality, over 800,000 children under five every year, all over the world. This pathology is mainly caused by viruses or bacteria. X-rays imaging analysis is one of the most used…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Helena Liz , Manuel Sánchez-Montañés , Alfredo Tagarro , Sara Domínguez-Rodríguez , Ron Dagan , David Camacho

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a gene editing technology that has revolutionized the fields of biology and medicine. However, one of the challenges of using CRISPR is predicting the on-target efficacy…

Machine Learning · Computer Science 2024-03-06 Mohammad Rostami , Amin Ghariyazi , Hamed Dashti , Mohammad Hossein Rohban , Hamid R. Rabiee

Advanced automated AI techniques allow us to classify protein sequences and discern their biological families and functions. Conventional approaches for classifying these protein families often focus on extracting N-Gram features from the…

Quantitative Methods · Quantitative Biology 2024-10-24 Bahar Ali , Anwar Shah , Malik Niaz , Musadaq Mansoord , Sami Ullah , Muhammad Adnan

The worldwide increase of antimicrobial resistance (AMR) is a serious threat to human health. To avert the spread of AMR, fast reliable diagnostics tools that facilitate optimal antibiotic stewardship are an unmet need. In this regard,…

An ensemble method that fuses the output decision vectors of multiple feedforward-designed convolutional neural networks (FF-CNNs) to solve the image classification problem is proposed in this work. To enhance the performance of the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Yueru Chen , Yijing Yang , Wei Wang , C. -C. Jay Kuo

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

The rise of Antimicrobial Resistance, particularly Multi-Drug Resistance (MDR), presents a critical challenge for clinical decision-making due to limited treatment options and delays in conventional susceptibility testing. This study…

Machine Learning · Computer Science 2026-03-03 Santanam Wishal , Riad Sahara

Whole genome sequencing (WGS) is quickly becoming the customary means for identification of antimicrobial resistance (AMR) due to its ability to obtain high resolution information about the genes and mechanisms that are causing resistance…

Genomics · Quantitative Biology 2021-07-27 Mattia Prosperi , Simone Marini , Christina Boucher , Jiang Bian

Diabetes remains a significant health challenge globally, contributing to severe complications like kidney disease, vision loss, and heart issues. The application of machine learning (ML) in healthcare enables efficient and accurate disease…

Machine Learning · Computer Science 2025-05-13 Mahade Hasan , Farhana Yasmin

The translation of comparative genomics into clinical decision support tools often depends on the quality of sequence alignments. However, currently used methods of multiple sequence alignments suffer from significant biases and problems…

Genomics · Quantitative Biology 2023-11-30 Manal Helal , Vitali Sintchenko

Machine learning, and representation learning in particular, has the potential to facilitate drug discovery by screening billions of compounds. For example, a successful approach is representing the molecules as a graph and utilizing graph…

Quantitative Methods · Quantitative Biology 2023-04-17 Ronen Taub , Tanya Wasserman , Yonatan Savir

With the rising prevalence of cardiovascular diseases, electrocardiograms (ECG) remain essential for the non-invasive detection of cardiac abnormalities. This study presents a comprehensive evaluation of deep neural network architectures…

Signal Processing · Electrical Eng. & Systems 2026-02-23 Yun Song , Wenjia Zheng , Tiedan Chen , Ziyu Wang , Jiazhao Shi , Yisong Chen

Antimicrobial resistance (AMR) is projected to cause up to 10 million deaths annually by 2050, underscoring the urgent need for new antibiotics. Here we present ApexAmphion, a deep-learning framework for de novo design of antibiotics that…

Deep Learning (DL) and specifically CNN models have become a de facto method for a wide range of vision tasks, outperforming traditional machine learning (ML) methods. Consequently, they drew a lot of attention in the neuroimaging field in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Benoit Dufumier , Pietro Gori , Ilaria Battaglia , Julie Victor , Antoine Grigis , Edouard Duchesnay

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Whole brain segmentation using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address this problem, previous DL methods proposed to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-22 Pierrick Coupé , Boris Mansencal , Michaël Clément , Rémi Giraud , Baudouin Denis de Senneville , Vinh-Thong Ta , Vincent Lepetit , José V. Manjon

AMRScan is a hybrid bioinformatics toolkit implemented in both R and [Nextflow](https://www.nextflow.io/) for the rapid and reproducible detection of antimicrobial resistance (AMR) genes from next-generation sequencing (NGS) data. The…

Genomics · Quantitative Biology 2025-07-14 Kaitao Lai

In this paper we propose cross-modal convolutional neural networks (X-CNNs), a novel biologically inspired type of CNN architectures, treating gradient descent-specialised CNNs as individual units of processing in a larger-scale network…

Machine Learning · Statistics 2017-09-26 Petar Veličković , Duo Wang , Nicholas D. Lane , Pietro Liò

Self-assembly of dilute sequence-defined macromolecules is a complex phenomenon in which the local arrangement of chemical moieties can lead to the formation of long-range structure. The dependence of this structure on the sequence…

Soft Condensed Matter · Physics 2022-06-08 Debjyoti Bhattacharya , Devon C. Kleeblatt , Antonia Statt , Wesley F. Reinhart

Convolutional Networks have dominated the field of computer vision for the last ten years, exhibiting extremely powerful feature extraction capabilities and outstanding classification performance. The main strategy to prolong this trend…

Computer Vision and Pattern Recognition · Computer Science 2021-06-07 Javier Huertas-Tato , Alejandro Martín , Julián Fierrez , David Camacho