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DNA nanostructures with programmable shape and interactions can be used as building blocks for the self-assembly of crystalline materials with prescribed nanoscale features, holding a vast technological potential. Structural rigidity and…

Soft Condensed Matter · Physics 2019-01-30 Ryan A. Brady , William T. Kaufhold , Nicholas J. Brooks , Vito Foderà , Lorenzo Di Michele

Building structures with hierarchical order through the self-assembly of smaller blocks is not only a prerogative of nature, but also a strategy to design artificial materials with tailored functions. We explore in simulation the…

Soft Condensed Matter · Physics 2020-02-17 Santi Prestipino , Domenico Gazzillo , Gianmarco Munaò , Dino Costa

The self-assembly of complex structures from engineered subunits is a major goal of nanotechnology, but controlling their size becomes increasingly difficult in larger assemblies. Existing strategies present significant challenges, among…

DNA self-assembly is an important tool that has a wide range of applications such as building nanostructures, the transport of target virotherapies, and nano-circuitry. Tools from graph theory can be used to encode the biological process of…

Combinatorics · Mathematics 2023-10-09 Cory Johnson , Andrew Lavengood-Ryan

In contrast to most self-assembling synthetic materials, which undergo unbounded growth, many biological self-assembly processes are self-limited. That is, the assembled structures have one or more finite dimensions that are much larger…

Soft Condensed Matter · Physics 2022-05-25 Huang Fang , Botond Tyukodi , W. Benjamin Rogers , Michael F. Hagan

Nucleation is the rate-determining step in the kinetics of many self-assembly processes. However, the importance of nucleation in the kinetics of DNA-origami self-assembly, which involves both the binding of staple strands and the folding…

Soft Condensed Matter · Physics 2023-03-22 Alexander Cumberworth , Daan Frenkel , Aleks Reinhardt

Surface plasmon resonances generated in metallic nanostructures can be utilized to tailor electromagnetic fields. The precise spatial arrangement of such structures can result in surprising optical properties that are not found in any…

Most binary superlattices created using DNA functionalization or other approaches rely on particle size differences to achieve compositional order and structural diversity. Here we study two-dimensional (2D) assembly of DNA-functionalized…

Soft Condensed Matter · Physics 2017-03-13 Minseok Song , Yajun Ding , Hasan Zerze , Mark A. Snyder , Jeetain Mittal

Recent advancements in microbiology have motivated the study of the production of nanostructures with applications such as biomedical computing and molecular robotics. One way to construct these structures is to construct branched DNA…

Cells regulate gene expression in part by forming DNA-protein condensates in the nucleus. While existing theories describe the equilibrium size and stability of such condensates, their dynamics remain less understood. Here, we use…

Soft Condensed Matter · Physics 2025-12-22 Adam R. Lamson , Mohammadhossein Firouznia , Michael J. Shelley

Colloids that interact via a short-range attraction serve as the primary building blocks for a broad range of self-assembled materials. However, one of the well-known drawbacks to this strategy is that these building blocks rapidly and…

Soft Condensed Matter · Physics 2020-09-16 S. A. Mallory , M. L. Bowers , A. Cacciuto

Molecular building blocks interacting at the nanoscale organize spontaneously into stable mono- layers that display intriguing long-range ordering motifs on the surface of atomic substrates. The patterning process, if appropriately…

Mesoscale and Nanoscale Physics · Physics 2011-02-18 Marta Balbás Gambra , Carsten Rohr , Kathrin Gruber , Bianca Hermann , Thomas Franosch

Multi-component self-assembly mixtures offer the possibility of encoding multiple target structures with the same set of interacting components. Selective retrieval of one of the stored structures has been attempted by preparing an initial…

Soft Condensed Matter · Physics 2022-03-23 Arunkumar Bupathy , Daan Frenkel , Srikanth Sastry

Self-assembly processes are widespread in nature, and lie at the heart of many biological and physical phenomena. The characteristics of self-assembly building blocks determine the structures that they form. Two crucial properties are the…

Soft Condensed Matter · Physics 2018-09-11 S. Tesoro , S. E. Ahnert , A. S. Leonard

We study theoretically a binary system in which an attraction of unlike particles is combined with a type-independent soft core repulsion. The possible experimental implementation of the system is a mixture of DNA-covered colloids, in which…

Soft Condensed Matter · Physics 2007-05-23 Alexei V. Tkachenko

The assembly of colloidal cubic diamond is a challenging process since the shape and interaction parameters and the thermodynamic conditions where this structure is stable are elusive. The simultaneous use of shape-anisotropic particles and…

Soft Condensed Matter · Physics 2024-06-12 Susana Marín-Aguilar , Fabrizio Camerin , Marjolein Dijkstra

The miniaturization of machines towards the micron and nanoscales requires the development of joint-like elements that enable and constrain motion. We present a facile method to create colloidal joints, that is, anisotropic colloidal…

Soft Condensed Matter · Physics 2016-10-14 Indrani Chakraborty , Vera Meester , Casper van der Wel , Daniela J Kraft

Over the last decade, the field of programmable self-assembly has seen an explosion in the diversity of crystal lattices that can be synthesized from DNA-coated colloidal nanometer- and micrometer-scale particles. The prevailing wisdom has…

We report canonical and grand-canonical lattice Monte Carlo simulations of the self-assembly of addressable structures comprising hundreds of distinct component types. The nucleation behaviour, in the form of free-energy barriers to…

Soft Condensed Matter · Physics 2016-04-18 Aleks Reinhardt , Chon Pan Ho , Daan Frenkel

The cytoplasm is a heterogeneous mixture containing many types of proteins that self-assemble into a wide variety of complexes. The accuracy and speed of cytoplasmic self-assembly is astonishing because it involves the correct…

Statistical Mechanics · Physics 2025-11-21 Félix Benoist , Pablo Sartori