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Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…
In this paper we consider spatial networks that realize a balance between an infrastructure cost (the cost of wire needed to connect the network in space) and communication efficiency, measured by average shortest pathlength. A global…
Real networks are finite metric spaces. Yet the geometry induced by shortest path distances in a network is definitely not its only geometry. Other forms of network geometry are the geometry of latent spaces underlying many networks, and…
Reinforced elastic sheets surround us in daily life, from concrete shell buildings to biological structures such as the arthropod exoskeleton or the venation network of dicotyledonous plant leaves. Natural structures are often highly…
Inspired by studies on the airports' network and the physical Internet, we propose a general model of weighted networks via an optimization principle. The topology of the optimal network turns out to be a spanning tree that minimizes a…
It is widely believed that the formation of brain network structure is under the pressure of optimal trade-off between reducing wiring cost and promoting communication efficiency. However, the question of whether this trade-off exists in…
A fundamental understanding of the network architecture of the brain is necessary for the further development of theories explicating circuit function. Perhaps as a derivative of its initial application to abstract informational systems,…
The emergence of detailed maps of physical networks, like the brain connectome, vascular networks, or composite networks in metamaterials, whose nodes and links are physical entities, have demonstrated the limits of the current network…
The structural human connectome (i.e.\ the network of fiber connections in the brain) can be analyzed at ever finer spatial resolution thanks to advances in neuroimaging. Here we analyze several large data sets for the human brain network…
Data describing the three-dimensional structure of physical networks is increasingly available, leading to a surge of interest in network science to explore the relationship between the shape and connectivity of physical networks. We…
Understanding the optimization dynamics of neural networks is necessary for closing the gap between theory and practice. Stochastic first-order optimization algorithms are known to efficiently locate favorable minima in deep neural…
The loss surface of deep neural networks has recently attracted interest in the optimization and machine learning communities as a prime example of high-dimensional non-convex problem. Some insights were recently gained using spin glass…
Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…
High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…
Data is scaling exponentially in fields ranging from genomics to neuroscience to economics. A central question is: can modern machine learning methods be applied to construct predictive models of natural systems like cells and brains based…
Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…
We analyze the structure of networks minimizing the global resistance to flow (or dissipated energy) with respect to two different constraints: fixed total channel volume and fixed total channel surface area. First, we determine the shape…
Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…
Many foraging microorganisms rely upon cellular transport networks to deliver nutrients, fluid and organelles between different parts of the organism. Networked organisms ranging from filamentous fungi to slime molds demonstrate a…
While the optimization problem behind deep neural networks is highly non-convex, it is frequently observed in practice that training deep networks seems possible without getting stuck in suboptimal points. It has been argued that this is…