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Recent advancements in large language model (LLM) agents have significantly accelerated scientific discovery automation, yet concurrently raised critical ethical and safety concerns. To systematically address these challenges, we introduce…

Artificial Intelligence · Computer Science 2025-05-30 Kunlun Zhu , Jiaxun Zhang , Ziheng Qi , Nuoxing Shang , Zijia Liu , Peixuan Han , Yue Su , Haofei Yu , Jiaxuan You

Benchmarking AI systems in multi-turn interactive scenarios is essential for understanding their practical capabilities in real-world applications. However, existing evaluation protocols are highly heterogeneous, differing significantly in…

Computation and Language · Computer Science 2026-03-25 Qi Jia , Haodong Zhao , Dun Pei , Xiujie Song , Shibo Wang , Zijian Chen , Zicheng Zhang , Xiangyang Zhu , Guangtao Zhai

The rapid evolution of artificial intelligence, particularly large language models, presents unprecedented opportunities for materials science research. We proposed and developed an AI materials scientist named MatPilot, which has shown…

Physics and Society · Physics 2024-11-14 Ziqi Ni , Yahao Li , Kaijia Hu , Kunyuan Han , Ming Xu , Xingyu Chen , Fengqi Liu , Yicong Ye , Shuxin Bai

Agentic AI is rapidly advancing in healthcare and biomedical research. However, in medical image analysis, their performance and adoption remain limited due to the lack of a robust ecosystem, insufficient toolsets, and the absence of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Songhao Li , Jonathan Xu , Tiancheng Bao , Yuxuan Liu , Yuchen Liu , Yihang Liu , Lilin Wang , Wenhui Lei , Sheng Wang , Yinuo Xu , Yan Cui , Jialu Yao , Shunsuke Koga , Zhi Huang

Existing automated research systems operate as stateless, linear pipelines -- generating outputs without maintaining any persistent understanding of the research landscape they navigate. They process papers sequentially, propose ideas…

Artificial Intelligence · Computer Science 2026-03-27 Yunbo Long

Large language models (LLMs) have moved far beyond their initial form as simple chatbots, now carrying out complex reasoning, planning, writing, coding, and research tasks. These skills overlap significantly with those that human scientists…

AI-based design tools are proliferating in professional software to assist engineering and industrial designers in complex manufacturing and design tasks. These tools take on more agentic roles than traditional computer-aided design tools…

Human-Computer Interaction · Computer Science 2023-03-02 Frederic Gmeiner , Humphrey Yang , Lining Yao , Kenneth Holstein , Nikolas Martelaro

The rapid advancements in Generative AI and Large Language Models promise to transform the way research is conducted, potentially offering unprecedented opportunities to augment scholarly workflows. However, effectively integrating AI into…

Tool-integrated LLMs can retrieve, compute, and take real-world actions via external tools, but reliability remains a key bottleneck. We argue that failures stem from both tool-use accuracy (how well an agent invokes a tool) and intrinsic…

Artificial Intelligence · Computer Science 2026-04-02 Hy Dang , Quang Dao , Meng Jiang

Scientific workflows in computational chemistry and materials science typically involve multiple interdependent steps, such as model preparation, system construction, simulation execution, and data analysis, that researchers have refined…

Artificial intelligence (AI) is being increasingly applied to scientific research, but its benefits remain unevenly distributed across different communities and disciplines. While technical challenges such as limited data, fragmented…

Machine Learning · Computer Science 2026-03-17 Georgia Channing , Avijit Ghosh

While previous AI Scientist systems can generate novel findings, they often lack the focus to produce scientifically valuable contributions that address pressing human-defined challenges. We introduce DeepScientist, a system designed to…

Computation and Language · Computer Science 2025-10-01 Yixuan Weng , Minjun Zhu , Qiujie Xie , Qiyao Sun , Zhen Lin , Sifan Liu , Yue Zhang

Leveraging Artificial Intelligence (AI) in decision support systems has disproportionately focused on technological advancements, often overlooking the alignment between algorithmic outputs and human expectations. A human-centered…

Human-Computer Interaction · Computer Science 2024-03-20 Catalina Gomez , Sue Min Cho , Shichang Ke , Chien-Ming Huang , Mathias Unberath

Open Artificial Intelligence (Open source AI) collaboratives offer alternative pathways for how AI can be developed beyond well-resourced technology companies and who can be a part of the process. To understand how and why they work and…

Computers and Society · Computer Science 2023-01-23 Jennifer Ding , Christopher Akiki , Yacine Jernite , Anne Lee Steele , Temi Popo

The rapid growth of scientific literature has made manual extraction of structured knowledge increasingly impractical. To address this challenge, we introduce SCILIRE, a system for creating datasets from scientific literature. SCILIRE has…

Computation and Language · Computer Science 2026-03-16 Necva Bölücü , Jessica Irons , Changhyun Lee , Brian Jin , Maciej Rybinski , Huichen Yang , Andreas Duenser , Stephen Wan

Development in Artificial Intelligence (AI) has accelerated scientific discovery. Alongside recent AI-oriented Nobel prizes, these trends establish the role of AI tools in science. This advancement raises questions about the potential…

Computers and Society · Computer Science 2025-12-02 Qianyue Hao , Fengli Xu , Yong Li , James Evans

Modern science is reaching a critical inflection point. Instruments across disciplines, from particle physics and astronomy to genomics and climate modeling, now produce data of such scale, diversity, and interdependence that traditional…

High Energy Physics - Experiment · Physics 2026-03-10 Ke Li , Beijiang Liu , Bruce Mellado , Changzheng Yuan , Zhengde Zhang

The convergence of artificial intelligence (AI) and synthetic biology is rapidly accelerating the pace of biological discovery and engineering. AI techniques, such as large language models and biological design tools, are enabling the…

Other Quantitative Biology · Quantitative Biology 2024-05-01 Cindy Vindman , Benjamin Trump , Christopher Cummings , Madison Smith , Alexander J. Titus , Ken Oye , Valentina Prado , Eyup Turmus , Igor Linkov
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