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In many scientific studies, it becomes increasingly important to delineate the causal pathways through a large number of mediators, such as genetic and brain mediators. Structural equation modeling (SEM) is a popular technique to estimate…

Machine Learning · Statistics 2016-03-28 Yi Zhao , Xi Luo

Stochastic differential equation mixed-effects models (SDEMEMs) are flexible hierarchical models that are able to account for random variability inherent in the underlying time-dynamics, as well as the variability between experimental units…

Computation · Statistics 2021-01-22 Samuel Wiqvist , Andrew Golightly , Ashleigh T. McLean , Umberto Picchini

A mixed data frame (MDF) is a table collecting categorical, numerical and count observations. The use of MDF is widespread in statistics and the applications are numerous from abundance data in ecology to recommender systems. In many cases,…

Methodology · Statistics 2019-03-27 Geneviève Robin , Olga Klopp , Julie Josse , Éric Moulines , Robert Tibshirani

Modern societies have an abundance of data yet good system models are rare. Unfortunately, many of the current system identification and machine learning techniques fail to generalize outside of the training set, producing models that…

Systems and Control · Electrical Eng. & Systems 2023-11-27 Gabriel F. Machado , Morgan Jones

We focus on the problem of estimating the change in the dependency structures of two $p$-dimensional Gaussian Graphical models (GGMs). Previous studies for sparse change estimation in GGMs involve expensive and difficult non-smooth…

Machine Learning · Computer Science 2018-05-24 Beilun Wang , Arshdeep Sekhon , Yanjun Qi

In machine learning and data mining, linear models have been widely used to model the response as parametric linear functions of the predictors. To relax such stringent assumptions made by parametric linear models, additive models consider…

Machine Learning · Statistics 2017-10-18 Sheng Chen , Arindam Banerjee

Traditional nonparametric estimation methods often lead to a slow convergence rate in large dimensions and require unrealistically enormous sizes of datasets for reliable conclusions. We develop an approach based on partial derivatives,…

Methodology · Statistics 2024-08-20 Xiaowu Dai

Consider a multi-variate time series $(X_t)_{t=0}^{T}$ where $X_t \in \mathbb{R}^d$ which may represent spike train responses for multiple neurons in a brain, crime event data across multiple regions, and many others. An important challenge…

Machine Learning · Statistics 2018-01-26 Hao Henry Zhou , Garvesh Raskutti

Choice models, which capture popular preferences over objects of interest, play a key role in making decisions whose eventual outcome is impacted by human choice behavior. In most scenarios, the choice model, which can effectively be viewed…

Methodology · Statistics 2011-09-22 Vivek F. Farias , Srikanth Jagabathula , Devavrat Shah

Large language models possess strong chemical reasoning capabilities, making them effective molecular editors. However, property-relevant information is implicitly entangled across their dense hidden states, providing no explicit handle for…

Machine Learning · Computer Science 2026-05-12 Mingxu Zhang , Yuhan Li , Lujundong Li , Dazhong Shen , Hui Xiong , Ying Sun

An efficient method for solving large nonlinear problems combines Newton solvers and Domain Decomposition Methods (DDM). In the DDM framework, the boundary conditions can be chosen to be primal, dual or mixed. The mixed approach presents…

Numerical Analysis · Mathematics 2018-02-07 Camille Negrello , Pierre Gosselet , Christian Rey

A daunting challenge faced by modern biological sciences is finding an efficient and computationally feasible approach to deal with the curse of high dimensionality. The problem becomes even more severe when the research focus is on…

Methodology · Statistics 2013-04-16 Hung Hung , Yu-Tin Lin , Pengwen Chen , Chen-Chien Wang , Su-Yun Huang , Jung-Ying Tzeng

Training neural network models with discrete (categorical or structured) latent variables can be computationally challenging, due to the need for marginalization over large or combinatorial sets. To circumvent this issue, one typically…

Machine Learning · Computer Science 2020-12-29 Gonçalo M. Correia , Vlad Niculae , Wilker Aziz , André F. T. Martins

Neural Additive Models (NAMs) have recently demonstrated promising predictive performance while maintaining interpretability. However, their capacity is limited to capturing only first-order feature interactions, which restricts their…

Machine Learning · Computer Science 2025-11-17 Minkyu Kim , Hyun-Soo Choi , Jinho Kim

Local features at neighboring spatial positions in feature maps have high correlation since their receptive fields are often overlapped. Self-attention usually uses the weighted sum (or other functions) with internal elements of each local…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Yang Du , Chunfeng Yuan , Bing Li , Lili Zhao , Yangxi Li , Weiming Hu

Sharpness-aware minimization (SAM) seeks the minima with a flat loss landscape to improve the generalization performance in machine learning tasks, including fine-tuning. However, its extra parameter perturbation step doubles the…

Machine Learning · Computer Science 2026-02-11 Yifei Cheng , Xianglin Yang , Guoxia Wang , Chao Huang , Fei Ma , Dianhai Yu , Xiaochun Cao , Li Shen

Multi-task learning is a widely used technique for harnessing information from various tasks. Recently, the sparse orthogonal factor regression (SOFAR) framework, based on the sparse singular value decomposition (SVD) within the coefficient…

Methodology · Statistics 2025-07-02 Zemin Zheng , Xin Zhou , Yingying Fan , Jinchi Lv

Recently, sparse autoencoders (SAEs) have emerged as a promising technique for interpreting activations in foundation models by disentangling features into a sparse set of concepts. However, identifying the optimal level of sparsity for…

Machine Learning · Computer Science 2026-04-17 Dongsheng Wang , Jinsen Zhang , Dawei Su , Hui Huang

In this paper, we introduce a novel high-dimensional Factor-Adjusted sparse Partially Linear regression Model (FAPLM), to integrate the linear effects of high-dimensional latent factors with the nonparametric effects of low-dimensional…

Methodology · Statistics 2025-01-14 Yanmei Shi , Meiling Hao , Yanlin Tang , Xu Guo

Deep Neural Networks use thousands of mostly incomprehensible features to identify a single class, a decision no human can follow. We propose an interpretable sparse and low dimensional final decision layer in a deep neural network with…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Thomas Norrenbrock , Marco Rudolph , Bodo Rosenhahn