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Purpose: To assess the alignment of GPT-4-based evaluation to human clinician experts, for the evaluation of responses to ophthalmology-related patient queries generated by fine-tuned LLM chatbots. Methods: 400 ophthalmology questions and…

Artificial Intelligence · Computer Science 2024-02-16 Ting Fang Tan , Kabilan Elangovan , Liyuan Jin , Yao Jie , Li Yong , Joshua Lim , Stanley Poh , Wei Yan Ng , Daniel Lim , Yuhe Ke , Nan Liu , Daniel Shu Wei Ting

As large language models (LLMs) become more common in educational tools and programming environments, questions arise about how these systems should interact with users. This study investigates how different interaction styles with…

Human-Computer Interaction · Computer Science 2025-07-08 Kai Deng

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Large language models (LLMs) have made rapid improvement on medical benchmarks, but their unreliability remains a persistent challenge for safe real-world uses. To design for the use LLMs as a category, rather than for specific models,…

Computation and Language · Computer Science 2024-10-14 Andrew M. Bean , Karolina Korgul , Felix Krones , Robert McCraith , Adam Mahdi

Objective: To evaluate the efficiency of large language models (LLMs) such as ChatGPT to assist in diagnosing neuro-ophthalmic diseases based on detailed case descriptions. Methods: We selected 22 different case reports of neuro-ophthalmic…

Computers and Society · Computer Science 2023-09-25 Yeganeh Madadi , Mohammad Delsoz , Priscilla A. Lao , Joseph W. Fong , TJ Hollingsworth , Malik Y. Kahook , Siamak Yousefi

Matching patients to clinical trial options is critical for identifying novel treatments, especially in oncology. However, manual matching is labor-intensive and error-prone, leading to recruitment delays. Pipelines incorporating large…

Computation and Language · Computer Science 2025-09-25 Braxton A. Morrison , Madhumita Sushil , Jacob S. Young

Large Language Models (LLMs) like ChatGPT have demonstrated amazing capabilities in comprehending user intents and generate reasonable and useful responses. Beside their ability to chat, their capabilities in various natural language…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

General purpose Large Language Models (LLM) such as the Generative Pretrained Transformer (GPT) and Large Language Model Meta AI (LLaMA) have attracted much attention in recent years. There is strong evidence that these models can perform…

Computation and Language · Computer Science 2024-04-25 Hossein Salami , Brandye Smith-Goettler , Vijay Yadav

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Multimodal large language models (MLLMs) have demonstrated promise on publicly available dermatology benchmarks. However, benchmark performance may not generalize to real-world dermatologic decision-making. To quantify this…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Roy Jiang , Hyunjae Kim , Zhenyue Qin , Morten Lee , Margaret MacGibeny , Ailish Hanly , Angela Sadlowski , Shanin Chowdhury , Xuguang Ai , Jeffrey Gehlhausen , Qingyu Chen

Background: Rapid advancements in natural language processing have led to the development of large language models with the potential to revolutionize mental health care. These models have shown promise in assisting clinicians and providing…

Computation and Language · Computer Science 2024-05-16 Birger Moell

The adoption of Large Language Models (LLMs) for code generation in data science offers substantial potential for enhancing tasks such as data manipulation, statistical analysis, and visualization. However, the effectiveness of these models…

Software Engineering · Computer Science 2024-11-20 Nathalia Nascimento , Everton Guimaraes , Sai Sanjna Chintakunta , Santhosh Anitha Boominathan

Background: Artificial intelligence language models have shown promise in various applications, including assisting with clinical decision-making as demonstrated by strong performance of large language models on medical licensure exams.…

Computation and Language · Computer Science 2023-05-10 Timothy Poterucha , Pierre Elias , Christopher M. Haggerty

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

This paper presents an in-depth analysis of the performance of seven different Large Language Models (LLMs) in solving a diverse set of math advanced calculus problems. The study aims to evaluate these models' accuracy, reliability, and…

Computation and Language · Computer Science 2025-03-07 In Hak Moon

As educational systems evolve, ensuring that assessment items remain aligned with content standards is essential for maintaining fairness and instructional relevance. Traditional human alignment reviews are accurate but slow and…

Artificial Intelligence · Computer Science 2025-11-26 Farzan Karimi-Malekabadi , Pooya Razavi , Sonya Powers

Large Language Models (LLMs) have revolutionized the field of Natural Language Processing thanks to their ability to reuse knowledge acquired on massive text corpora on a wide variety of downstream tasks, with minimal (if any) tuning steps.…

Computation and Language · Computer Science 2024-07-12 Flavio Petruzzellis , Alberto Testolin , Alessandro Sperduti

Despite Large Language Models (LLMs) like GPT-4 achieving impressive results in function-level code generation, they struggle with repository-scale code understanding (e.g., coming up with the right arguments for calling routines),…

Large Language Models (LLMs) are increasingly explored for educational tasks such as grading, yet their alignment with human evaluation in real classrooms remains underexamined. In this study, we investigate the feasibility of using an LLM…

Computation and Language · Computer Science 2025-11-19 Grace Byun , Swati Rajwal , Jinho D. Choi