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With the recent Nobel Prize awarded for radical advances in protein discovery, foundation models (FMs) for exploring large combinatorial spaces promise to revolutionize many scientific fields. Artificial Life (ALife) has not yet integrated…

Artificial Intelligence · Computer Science 2025-05-20 Akarsh Kumar , Chris Lu , Louis Kirsch , Yujin Tang , Kenneth O. Stanley , Phillip Isola , David Ha

Large Language Model (LLM)-guided evolutionary search is increasingly used for automated algorithm discovery, yet most current methods track search progress primarily through executable programs and scalar fitness. Even when…

Computation and Language · Computer Science 2026-05-11 Sichun Luo , Yi Huang , Haochen Luo , Fengyuan Liu , Guanzhi Deng , Lei Li , Qinghua Yao , Zefa Hu , Junlan Feng , Qi Liu

Large Language Models (LLMs) have unveiled remarkable capabilities in understanding and generating both natural language and code, but LLM reasoning is prone to hallucination and struggle with complex, novel scenarios, often getting stuck…

Neural and Evolutionary Computing · Computer Science 2025-05-12 Antonio Jimeno Yepes , Pieter Barnard

Optimization can be found in many real-life applications. Designing an effective algorithm for a specific optimization problem typically requires a tedious amount of effort from human experts with domain knowledge and algorithm design…

Neural and Evolutionary Computing · Computer Science 2023-11-28 Fei Liu , Xialiang Tong , Mingxuan Yuan , Qingfu Zhang

Deep reinforcement learning has achieved impressive success in control tasks. However, its policies, represented as opaque neural networks, are often difficult for humans to understand, verify, and debug, which undermines trust and hinders…

Machine Learning · Computer Science 2026-03-11 Qinglong Hu , Xialiang Tong , Mingxuan Yuan , Fei Liu , Zhichao Lu , Qingfu Zhang

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

Neural and Evolutionary Computing · Computer Science 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

Pre-trained large language models (LLMs) exhibit powerful capabilities for generating natural text. Evolutionary algorithms (EAs) can discover diverse solutions to complex real-world problems. Motivated by the common collective and…

Neural and Evolutionary Computing · Computer Science 2025-03-10 Chao Wang , Jiaxuan Zhao , Licheng Jiao , Lingling Li , Fang Liu , Shuyuan Yang

We present a semantic feedback framework that enables natural language to guide the evolution of artificial life systems. Integrating a prompt-to-parameter encoder, a CMA-ES optimizer, and CLIP-based evaluation, the system allows user…

Artificial Intelligence · Computer Science 2025-07-08 Shuowen Li , Kexin Wang , Minglu Fang , Danqi Huang , Ali Asadipour , Haipeng Mi , Yitong Sun

We present a framework for optimizing prompts in vision-language models to elicit multimodal reasoning without model retraining. Using an evolutionary algorithm to guide prompt updates downstream of visual tasks, our approach improves upon…

Computation and Language · Computer Science 2025-04-01 Sid Bharthulwar , John Rho , Katrina Brown

Foundation models (FMs), such as GPT-4 and AlphaFold, are reshaping the landscape of scientific research. Beyond accelerating tasks such as hypothesis generation, experimental design, and result interpretation, they prompt a more…

Machine Learning · Computer Science 2025-10-20 Fan Liu , Jindong Han , Tengfei Lyu , Weijia Zhang , Zhe-Rui Yang , Lu Dai , Cancheng Liu , Hao Liu

Large Language Models (LLMs) have taken the field of AI by storm, but their adoption in the field of Artificial Life (ALife) has been, so far, relatively reserved. In this work we investigate the potential synergies between LLMs and ALife,…

Inspired by biological and cultural evolution, there have been many attempts to explore and elucidate the necessary conditions for open-endedness in artificial intelligence and artificial life. Using a continuous cellular automata called…

Neural and Evolutionary Computing · Computer Science 2023-04-13 Bert Wang-Chak Chan

Evolve-based agent such as AlphaEvolve is one of the notable successes in using Large Language Models (LLMs) to build AI Scientists. These agents tackle open-ended scientific problems by iteratively improving and evolving programs,…

Machine Learning · Computer Science 2026-03-31 Yongqiang Chen , Chenxi Liu , Zhenhao Chen , Tongliang Liu , Bo Han , Kun Zhang

Feature transformation aims to reconstruct the feature space of raw features to enhance the performance of downstream models. However, the exponential growth in the combinations of features and operations poses a challenge, making it…

Machine Learning · Computer Science 2024-12-19 Nanxu Gong , Chandan K. Reddy , Wangyang Ying , Haifeng Chen , Yanjie Fu

Active learning (AL) accelerates scientific discovery by prioritizing the most informative experiments, but traditional machine learning (ML) models used in AL suffer from cold-start limitations and domain-specific feature engineering,…

Machine Learning · Computer Science 2025-12-05 Hongchen Wang , Rafael Espinosa Castañeda , Jay R. Werber , Yao Fehlis , Edward Kim , Jason Hattrick-Simpers

Evolutionary algorithms excel in solving complex optimization problems, especially those with multiple objectives. However, their stochastic nature can sometimes hinder rapid convergence to the global optima, particularly in scenarios…

Neural and Evolutionary Computing · Computer Science 2024-05-10 Zeyi Wang , Songbai Liu , Jianyong Chen , Kay Chen Tan

Search has been proposed as an effective method for self-improving language models and agentic systems, both for post-training sample generation and for inference. However, widely used methods such as best-of-N sampling and tree search face…

Computation and Language · Computer Science 2026-05-28 Guowei Xu , Zhenting Qi , Huangyuan Su , Weirui Ye , Himabindu Lakkaraju , Sham M. Kakade , Yilun Du

The paradigm of automated program generation is shifting from one-shot generation to inference-time search, where Large Language Models (LLMs) function as semantic mutation operators within evolutionary loops. While effective, these systems…

Neural and Evolutionary Computing · Computer Science 2026-02-24 Mert Cemri , Shubham Agrawal , Akshat Gupta , Shu Liu , Audrey Cheng , Qiuyang Mang , Ashwin Naren , Lutfi Eren Erdogan , Koushik Sen , Matei Zaharia , Alex Dimakis , Ion Stoica

Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling…

Sparse portfolio optimization is a fundamental yet challenging problem in quantitative finance, since traditional approaches heavily relying on historical return statistics and static objectives can hardly adapt to dynamic market regimes.…

Portfolio Management · Quantitative Finance 2025-07-24 Haochen Luo , Yuan Zhang , Chen Liu
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