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Computational determination of the equilibrium state of heterogeneous phospholipid mem-branes is a significant challenge. We wish to explore the rich phase diagram of these multi-component systems. However, the diffusion and mixing times in…

Biological Physics · Physics 2020-10-28 Yevhen K. Cherniavskyi , Arman Fathizadeh , Ron Elber , D. Peter Tieleman

We describe a method to compute photon-matter interaction and atomic dynamics with X-ray lasers using a hybrid code based on classical molecular dynamics and collisional-radiative calculations. The forces between the atoms are dynamically…

Model updating of engineering systems inevitably involves handling both aleatory or inherent randomness and epistemic uncertainties or uncertainities arising from a lack of knowledge or information about the system. Addressing these…

Applications · Statistics 2025-05-27 Sangwon Lee , Taro Yaoyama , Masaru Kitahara , Tatsuya Itoi

Two primary scalar auxiliary variable (SAV) approaches are widely applied for simulating gradient flow systems, i.e., the nonlinear energy-based approach and the Lagrange multiplier approach. The former guarantees unconditional energy…

Numerical Analysis · Mathematics 2024-11-27 Qiong-Ao Huang , Wei Jiang , Jerry Zhijian Yang , Cheng Yuan

MADNESS (multiresolution adaptive numerical environment for scientific simulation) is a high-level software environment for solving integral and differential equations in many dimensions that uses adaptive and fast harmonic analysis methods…

Deep generative models hold great promise for representing complex physical systems, but their deployment is currently limited by the lack of guarantees on the physical plausibility of the generated outputs. Ensuring that known physical…

Machine Learning · Computer Science 2026-03-13 Matthieu Blanke , Yongquan Qu , Sara Shamekh , Pierre Gentine

Large-scale molecular dynamics simulations with high accuracy have been increasingly popular for their capability to bridge the gap between atomistic modeling and mesoscale phenomena. Both machine learning potentials and enhanced sampling…

Computational Physics · Physics 2026-03-24 Haoting Zhang , Qiuhan Jia , Zhennan Zhang , Yijie Zhu , Zhongwei Zhang , Junjie Wang , Jiuyang Shi , Zheyong Fan , Jian Sun

Mixtures of linear dynamical systems (MoLDS) provide a path to model time-series data that exhibit diverse temporal dynamics across trajectories. However, its application remains challenging in complex and noisy settings, limiting its…

Machine Learning · Computer Science 2026-03-02 Lulu Gong , Shreya Saxena

Hybrid multiscale modelling has emerged as a useful framework for modelling complex biological phenomena. However, when accounting for stochasticity in the internal dynamics of agents, these models frequently become computationally…

Quantitative Methods · Quantitative Biology 2021-05-11 Daria Stepanova , Helen M. Byrne , Philip K. Maini , Tomás Alarcón

High-fidelity physics simulations are powerful tools in the design and optimization of charged particle accelerators. However, the computational burden of these simulations often limits their use in practice for design optimization and…

Accelerator Physics · Physics 2020-04-15 Auralee Edelen , Nicole Neveu , Yannick Huber , Mattias Frey , Christopher Mayes , Andreas Adelmann

Numerical methods are developed to simulate the dynamics of atoms in a Magneto-Optic Trap (MOT), based on the fluid description of ultracold gases under laser cooling and magnetic trapping forces. With this model, equilibrium hydrostatic…

Quantum Gases · Physics 2025-06-24 Francisco Raposo , Hugo Terças

We describe a combination of all-atom simulations with CABS, a well-established coarse-grained protein modeling tool, into a single multiscale protocol. The simulation method has been tested on the C-terminal beta hairpin of protein G, a…

Biological Physics · Physics 2013-08-13 Jacek Wabik , Sebastian Kmiecik , Dominik Gront , Maksim Kouza , Andrzej Kolinski

We developed a multiscale approach (MultiSCAAL) that integrates the potential of mean force (PMF) obtained from all-atomistic molecular dynamics simulations with a knowledge-based energy function for coarse-grained molecular simulations in…

Biological Physics · Physics 2010-05-10 Antonios Samiotakis , Dirar Homouz , Margaret S. Cheung

Conventional molecular dynamics (MD) simulation approaches, such as $\textit{ab initio}$ MD (AIMD) and empirical force field MD (EFFMD), face significant trade-offs between physical accuracy and computational efficiency. This work presents…

Disordered Systems and Neural Networks · Physics 2026-05-12 Hongyu Yan , Yong Wei , Minghan Chen , Hanning Chen

All-atom molecular dynamics has been recently proven a useful tool for the study of supramolecular polymers. While the high resolution offered by the atomistic models may allow for deep comprehension of the assembled structure, obtaining a…

Soft Condensed Matter · Physics 2018-04-20 Davide Bochicchio , Giovanni M. Pavan

The development of unsupervised Video Anomaly Detection (VAD) relies on technologies in the field of signal processing. Since the anomaly is quite ambiguous and unbounded, different detection demands may often be raised even in one…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Kai Cheng , Xinzhe Li , Lijuan Che

The virial expansion provides a non-perturbative view into the thermodynamics of quantum many-body systems in dilute regimes. While powerful, the expansion is challenging as calculating its coefficients at each order $n$ requires analyzing…

Quantum Gases · Physics 2023-02-13 Aleks J. Czejdo , Joaquin E. Drut , Yaqi Hou , Kaitlyn J. Morrell

Furthering our understanding of many of today's interesting problems in plasma physics---including plasma based acceleration and magnetic reconnection with pair production due to quantum electrodynamic effects---requires large-scale kinetic…

Computational Physics · Physics 2020-10-28 Kyle G. Miller , Roman P. Lee , Adam Tableman , Anton Helm , Ricardo A. Fonseca , Viktor K. Decyk , Warren B. Mori

Despite the remarkable success of diffusion models in text-to-image generation, their effectiveness in grounded visual editing and compositional control remains challenging. Motivated by advances in self-supervised learning and in-context…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Shreya Kadambi , Risheek Garrepalli , Shubhankar Borse , Munawar Hyatt , Fatih Porikli

Rich material data is complex, large and heterogeneous, integrating primary and secondary non-destructive testing data for spatial, spatio-temporal, as well as high-dimensional data analyses. Currently, materials experts mainly rely on…

Human-Computer Interaction · Computer Science 2025-05-13 Alexander Gall , Anja Heim , Eduard Gröller , Christoph Heinzl