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Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

Linear mixed models (LMMs) are used as an important tool in the data analysis of repeated measures and longitudinal studies. The most common form of LMMs utilize a normal distribution to model the random effects. Such assumptions can often…

Methodology · Statistics 2016-02-16 Hien D. Nguyen , Geoffrey J. McLachlan

As machine learning models are increasingly deployed in high-stakes domains, the need for interpretability has grown to meet strict regulatory and accountability constraints. Despite this interest, systematic evaluations of inherently…

Machine Learning · Computer Science 2026-03-27 Mattia Billa , Giovanni Orlandi , Veronica Guidetti , Federica Mandreoli

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

In this paper, we propose an approach to support the diagnosis of urinary tract diseases, with a focus on bladder cancer, using SHAP (SHapley Additive exPlanations)-based feature selection to enhance the transparency and effectiveness of…

Machine Learning · Computer Science 2025-10-24 Filipe Ferreira de Oliveira , Matheus Becali Rocha , Renato A. Krohling

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis

The success of machine learning algorithms heavily relies on the quality of samples and the accuracy of their corresponding labels. However, building and maintaining large, high-quality datasets is an enormous task. This is especially true…

Image and Video Processing · Electrical Eng. & Systems 2024-08-02 Mohammad Tariqul Islam , Jason W. Fleischer

The ability to collect and store ever more massive databases has been accompanied by the need to process them efficiently. In many cases, most observations have the same behavior, while a probable small proportion of these observations are…

Statistics Theory · Mathematics 2021-09-21 Myrto Limnios , Nathan Noiry , Stéphan Clémençon

Background: Mental stress and its consequent mental disorders (MDs) are significant public health issues. With the advent of machine learning (ML), there's potential to harness computational techniques for better understanding and…

An outlier is an observation or a data point that is far from rest of the data points in a given dataset or we can be said that an outlier is away from the center of mass of observations. Presence of outliers can skew statistical measures…

Machine Learning · Computer Science 2021-06-17 Amulya Agarwal , Nitin Gupta

This paper examines the problem of locating outlier columns in a large, otherwise low-rank, matrix. We propose a simple two-step adaptive sensing and inference approach and establish theoretical guarantees for its performance; our results…

Information Theory · Computer Science 2015-06-22 Xingguo Li , Jarvis Haupt

Outlier detection is critical in real applications to prevent financial fraud, defend network intrusions, or detecting imminent device failures. To reduce the human effort in evaluating outlier detection results and effectively turn the…

Machine Learning · Computer Science 2023-09-04 Yu Wang , Lei Cao , Yizhou Yan , Samuel Madden

Understanding why a model makes a certain prediction can be as crucial as the prediction's accuracy in many applications. However, the highest accuracy for large modern datasets is often achieved by complex models that even experts struggle…

Artificial Intelligence · Computer Science 2017-11-28 Scott Lundberg , Su-In Lee

With advanced data analytical techniques, efforts for more accurate decision support systems for disease prediction are on rise. Surveys by World Health Organization (WHO) indicate a great increase in number of diabetic patients and related…

Machine Learning · Computer Science 2017-06-27 Maham Jahangir , Hammad Afzal , Mehreen Ahmed , Khawar Khurshid , Raheel Nawaz

Hybrid methods have been shown to outperform pure statistical and pure deep learning methods at both forecasting tasks, and at quantifying the uncertainty associated with those forecasts (prediction intervals). One example is Multivariate…

Machine Learning · Computer Science 2022-02-28 Thabang Mathonsi , Terence L van Zyl

In recent years, two parallel research trends have emerged in machine learning, yet their intersections remain largely unexplored. On one hand, there has been a significant increase in literature focused on Individual Treatment Effect (ITE)…

Outlier detection is a significant area in data mining. It can be either used to pre-process the data prior to an analysis or post the processing phase (before visualization) depending on the effectiveness of the outlier and its importance.…

Machine Learning · Statistics 2021-06-22 Jacob John

Sparse estimation methods capable of tolerating outliers have been broadly investigated in the last decade. We contribute to this research considering high-dimensional regression problems contaminated by multiple mean-shift outliers which…

Methodology · Statistics 2025-10-21 Luca Insolia , Ana Kenney , Francesca Chiaromonte , Giovanni Felici

Outlier detection can serve as an extremely important tool for researchers from a wide range of fields. From the sectors of banking and marketing to the social sciences and healthcare sectors, outlier detection techniques are very useful…

Methodology · Statistics 2023-12-12 Efthymios Costa , Ioanna Papatsouma