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Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

Vision-language models (VLMs) have shown promise in 2D medical image analysis, but extending them to 3D remains challenging due to the high computational demands of volumetric data and the difficulty of aligning 3D spatial features with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yu Xin , Gorkem Can Ates , Kuang Gong , Wei Shao

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

Reliable face forgery detection algorithms are crucial for countering the growing threat of deepfake-driven disinformation. Previous research has demonstrated the potential of Multimodal Large Language Models (MLLMs) in identifying…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Siran Peng , Zipei Wang , Li Gao , Xiangyu Zhu , Tianshuo Zhang , Ajian Liu , Haoyuan Zhang , Zhen Lei

The scarcity of high-quality, labelled retinal imaging data, which presents a significant challenge in the development of machine learning models for ophthalmology, hinders progress in the field. Existing methods for synthesising Colour…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Junzhi Ning , Cheng Tang , Kaijing Zhou , Diping Song , Lihao Liu , Ming Hu , Wei Li , Huihui Xu , Yanzhou Su , Tianbin Li , Jiyao Liu , Jin Ye , Sheng Zhang , Yuanfeng Ji , Junjun He

Accurately segmenting blood vessels in retinal fundus images is crucial in the early screening, diagnosing, and evaluating some ocular diseases, yet it poses a nontrivial uncertainty for the segmentation task due to various factors such as…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yuanyuan Peng , Pengpeng Luan , Zixu Zhang

Multimodal medical image fusion (MMIF) extracts the most meaningful information from multiple source images, enabling a more comprehensive and accurate diagnosis. Achieving high-quality fusion results requires a careful balance of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Dan He , Weisheng Li , Guofen Wang , Yuping Huang , Shiqiang Liu

Multimodal large language models (MLLMs) typically extract visual features from the final layers of a pretrained Vision Transformer (ViT). This widespread deep-layer bias, however, is largely driven by empirical convention rather than…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Haoran Chen , Junyan Lin , Xinghao Chen , Yue Fan , Jianfeng Dong , Xin Jin , Hui Su , Jinlan Fu , Xiaoyu Shen

Classification and identification of the materials lying over or beneath the Earth's surface have long been a fundamental but challenging research topic in geoscience and remote sensing (RS) and have garnered a growing concern owing to the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Danfeng Hong , Lianru Gao , Naoto Yokoya , Jing Yao , Jocelyn Chanussot , Qian Du , Bing Zhang

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Multimodal LLMs (MLLMs) equip language models with visual capabilities by aligning vision encoders with language models. Existing methods to enhance the visual perception of MLLMs often involve designing more powerful vision encoders, which…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Zhuokun Chen , Jinwu Hu , Zeshuai Deng , Yufeng Wang , Bohan Zhuang , Mingkui Tan

While multimodal fusion has been extensively studied in Multimodal Sentiment Analysis (MSA), the role of fusion depth and multimodal capacity allocation remains underexplored. In this work, we position fusion depth, scalability, and…

Computation and Language · Computer Science 2025-04-16 Efthymios Georgiou , Vassilis Katsouros , Yannis Avrithis , Alexandros Potamianos

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Recent advancements in Multimodal Large Language Models (MLLMs) have significantly enhanced performance on 2D visual tasks. However, improving their spatial intelligence remains a challenge. Existing 3D MLLMs always rely on additional 3D or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Diankun Wu , Fangfu Liu , Yi-Hsin Hung , Yueqi Duan

Large vision-language models (VLMs) exhibit strong performance across various tasks. However, these VLMs encounter significant challenges when applied to the remote sensing domain due to the inherent differences between remote sensing…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yunkai Dang , Donghao Wang , Jiacheng Yang , Yifan Jiang , Meiyi Zhu , Yuekun Yang , Cong Wang , Qi Fan , Wenbin Li , Yang Gao

Large Vision-Language Models (LVLMs) commonly follow a paradigm that projects visual features and then concatenates them with text tokens to form a unified sequence input for Large Language Models (LLMs). However, this paradigm leads to a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xinyu Wei , Guoli Yang , Jialu Zhou , Mingyue Yang , Leqian Li , Kedi Zhang , Chunping Qiu

Modeling medical vessel-like anatomy is challenging due to its intricate topology and sensitivity to dataset shifts. Consequently, task-specific models often suffer from topological inconsistencies, including artificial disconnections and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Yaoyu Liu , Minghui Zhang , Xin You , Hanxiao Zhang , Yun Gu

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

We present MM1.5, a new family of multimodal large language models (MLLMs) designed to enhance capabilities in text-rich image understanding, visual referring and grounding, and multi-image reasoning. Building upon the MM1 architecture,…

Multimodal information is frequently available in medical tasks. By combining information from multiple sources, clinicians are able to make more accurate judgments. In recent years, multiple imaging techniques have been used in clinical…