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Stimulated Emission Depletion (STED) microscopy has emerged as a powerful technique providing visualization of biological structures at the molecular level in living samples. In this technique, the diffraction limit is broken by selectively…

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Microscopy is one of the most essential imaging techniques in life sciences. High-quality images are required in order to solve (potentially life-saving) biomedical research problems. Many microscopy techniques do not achieve sufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jan Aelterman , Jonas De Vylder , Hiep Luong , Yvan Saeys , Wilfried Philips

Structural phase separation in A$_x$Fe$_{2-y}$Se$_2$ system has been studied by different experimental techniques, however, it should be important to know how the electronic uniformity is influenced, on which length scale the electronic…

The performance of electron energy-loss spectrometers can often be limited by their electron-optical aberrations. Due to recent developments in high energy-resolution and momentum-resolved electron energy loss spectroscopy (EELS), there is…

Materials Science · Physics 2023-02-28 Yueming Guo , Andrew R. Lupini

Permutationally invariant polynomial (PIP) regression has been used to obtain machine-learned (ML) potential energy surfaces, including analytical gradients, for many molecules and chemical reactions. Recently, the approach has been…

Chemical Physics · Physics 2024-07-30 Paul L. Houston , Chen Qu , Apurba Nandi , Riccardo Conte , Qi Yu , Joel M. Bowman

Entangled photon pairs generated within integrated devices must often be spatially separated for their subsequent manipulation in quantum circuits. Separation that is both deterministic and universal can in principle be achieved through…

Quantum Physics · Physics 2015-12-29 Ryan P. Marchildon , Amr S. Helmy

One of the problems of producing instruments for Extremely Large Telescopes is that their size (and hence cost) scales rapidly with telescope aperture. To try to break this relation alternative new technologies have been proposed, such as…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 Robert James Harris , Jeremy Allington-Smith

In this two-part paper, we present a novel framework and methodology to analyze data from certain image-based biochemical assays, e.g., ELISPOT and Fluorospot assays. In this first part, we start by presenting a physical partial…

Signal Processing · Electrical Eng. & Systems 2018-10-19 Pol del Aguila Pla , Joakim Jaldén

Fast electrons spectromicroscopies enable to measure quantitatively the optical response of excitations with unrivaled spatial resolution. However, due to their inherently scalar nature, electron waves cannot access to polarization-related…

Optics · Physics 2021-05-26 Hugo Lourenço-Martins , Davy Gérard , Mathieu Kociak

We analyze the fundamental resolution of incoherent optical point sources from the perspective of a quantum detection problem: deciding whether the optical field on the image plane is generated by one source or two weaker sources with…

Quantum Physics · Physics 2019-11-07 Xiao-Ming Lu , Ranjith Nair , Mankei Tsang

Auger Photoelectron Coincidence Spectroscopy (APECS), in which the Auger spectra is measured in coincidence with the core level photoelectron, is capable of pulling difficult to observe low energy Auger peaks out of a large background due…

Materials Science · Physics 2014-05-29 S. Satyal , P. V. Joglekar , K. Shastry , S. Kalaskar , Q. Dong , S. L. Hulbert , R. A. Bartynksi , A. H. Weiss

We compare methods for signal classification applied to voltage traces from transition-edge sensors (TES) which are photon-number resolving detectors fundamental for accessing quantum advantages in information processing, communication and…

Instrumentation and Detectors · Physics 2025-09-09 Nicolas Dalbec-Constant , Guillaume Thekkadath , Duncan England , Benjamin Sussman , Thomas Gerrits , Nicolás Quesada

In this work we present a theoretical study of EELS (electron-energy-loss spectroscopy) experiments on the ${\rm C}_{60}$ molecule. Our treatment of the problem is based on the simple two-fluid model originally proposed for the description…

Mesoscale and Nanoscale Physics · Physics 2009-10-31 D. A. Gorokhov , R. A. Suris , V. V. Cheianov

In this paper, we propose a physics-inspired contrastive learning paradigm for low-light enhancement, called PIE. PIE primarily addresses three issues: (i) To resolve the problem of existing learning-based methods often training a LLE model…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Dong Liang , Zhengyan Xu , Ling Li , Mingqiang Wei , Songcan Chen

Oral cancer is a significant global health burden, and early detection remains a critical clinical need. Electrical impedance spectroscopy (EIS) offers a promising non-invasive approach for real-time tissue characterization, but…

Mixing phenomena in hyperspectral images depend on a variety of factors such as the resolution of observation devices, the properties of materials, and how these materials interact with incident light in the scene. Different parametric and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Tales Imbiriba , José Carlos Moreira Bermudez , Cédric Richard , Jean-Yves Tourneret

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures…

Signal Processing · Electrical Eng. & Systems 2023-12-14 Matthew McDougall , Hezam Albaqami , Ghulam Mubashar Hassan , Amitava Datta

Imaging the features of a sample using Positron Annihilation Spectroscopy (PAS) is currently achieved by rastering, i.e. by scanning the sample surface with a sharply focused positron beam. However, a beam of arbitrary shape (sculpted beam)…

Instrumentation and Detectors · Physics 2024-02-05 Francesco Guatieri

Spatial-mode demultiplexing (SPADE) has recently been adopted to measure the separation in the transverse plane between two incoherent point-like sources. It has been argued that this approach may yield extraordinary performances in the…