Related papers: Contour-informed inter-patient deformable registra…

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Background: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation in MR-guided adaptive radiotherapy (MRgART). This study trained and evaluated a deep learning DIR method for domain invariant…

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Various multi-modal imaging sensors are currently involved at different steps of an interventional therapeutic work-flow. Cone beam computed tomography (CBCT), computed tomography (CT) or Magnetic Resonance (MR) images thereby provides…

A renewed interest in upright therapy is currently driven by the availability of upright positioning and imaging systems. Aside from reduced cost, upright positioning possibly provides clinical advantages. The comparison between upright and…

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated…

The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference…

Regularization is essential in deformable image registration (DIR) to ensure that the estimated Deformation Vector Field (DVF) remains smooth, physically plausible, and anatomically consistent. However, fine-tuning regularization parameters…

Deformable Image Registration (DIR) of MR and CT images is one of the most challenging registration task, due to the inherent structural differences of the modalities and the missing dense ground truth. Recently cycle Generative Adversarial…