Related papers: Dynamic transitions for fast joint acquisition and…
Purpose: To develop a motion-robust and geometrically-accurate quantitative CEST approach using radial k-space sampling, locally low-rank reconstruction and neural network quantification. Methods: The acquisition schedule was generated via…
Purpose: To develop an automated machine-learning-based method for the discovery of rapid and quantitative chemical exchange saturation transfer (CEST) MR fingerprinting acquisition and reconstruction protocols. Methods: An MR physics…
Purpose: To develop a model-based deep neural network for high-quality image reconstruction of undersampled multi-coil chemical exchange saturation transfer (CEST) data. Theory and Methods: Inspired by the variational network, the CEST…
Purpose: To develop and validate a framework for rapid, accurate, and reproducible whole-brain, multi-pool chemical exchange saturation transfer (CEST) imaging at 3T, addressing challenges of long acquisition times and confounding factors.…
Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema. However, the inherently dynamic nature of the heart imposes…
Purpose: To understand the influence of various acquisition parameters on the ability of CEST MR-Fingerprinting (MRF) to discriminate different chemical exchange parameters and to provide tools for optimal acquisition schedule design and…
Endogenous chemical exchange saturation transfer (CEST) effects are always diluted by competing effects such as direct water proton saturation (spillover) and macromolecular magnetization transfer (MT). This leads to T2-and MT-shine-through…
In radial fast spin-echo MRI, a set of overlapping spokes with an inconsistent T2 weighting is acquired, which results in an averaged image contrast when employing conventional image reconstruction techniques. This work demonstrates that…
CEST suffers from two main problems long acquisitin times or restricted coverage as well as incoherent protocol settings. In this paper we give suggestions on how to optimise your protocol settings fro CEST and present one setting for APT…
Purpose: ECG and respiratory-gated preclinical cardiac CEST-MRI acquisitions are difficult due to variable saturation recovery with T1, RF interference in the ECG signal, and offset-to-offset variation in Z-magnetization and cardiac phase…
Purpose: To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative chemical exchange saturation transfer (CEST) imaging. Methods: We implemented a CEST-MRF method to quantify the chemical exchange rate and volume…
Multi-contrast images are commonly acquired together to maximize complementary diagnostic information, albeit at the expense of longer scan times. A time-efficient strategy to acquire high-quality multi-contrast images is to accelerate…
In many biomedical applications, measurements are not freely available at inference time: each laboratory test, imaging modality, or assessment incurs financial cost, time burden, or patient risk. Longitudinal active feature acquisition…
Quantitative cardiac magnetic resonance T1 and T2 mapping enable myocardial tissue characterisation but the lengthy scan times restrict their widespread clinical application. We propose a deep learning method that incorporates a time…
Purpose: Separation of different CEST signals in the Z-spectrum is a challenge especially at low field strengths where amide, amine, and NOE peaks coalesce with each other or with the water peak. The purpose of this work is to investigate…
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…
A new method of measuring long spin-lattice relaxation times ($T_1$) is proposed. Being a single scan technique, the method is at least one order of magnitude faster than the conventional technique. This method (Single-Scan or Slice…
Chemical exchange saturation transfer (CEST) is widely used for enhancing the solution NMR signatures of magnetically-dilute spin pools; in particular species at low concentrations undergoing chemical exchanges with an abundant spin pool.…
CEST has proven to be a valuable technique for the detection of hyperpolarized xenon-based functionalized contrast agents. Additional information can be encoded in the spectral dimension, allowing the simultaneous detection of multiple…
When a measurement falls outside the quantization or measurable range, it becomes saturated and cannot be used in classical reconstruction methods. For example, in C-arm angiography systems, which provide projection radiography,…