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Generalized Additive Models (GAMs) balance predictive accuracy and interpretability, but manually configuring their structure is challenging. We propose using the multi-objective genetic algorithm NSGA-II to automatically optimize GAMs,…

Machine Learning · Computer Science 2026-02-19 Kaaustaaub Shankar , Kelly Cohen

Genetic algorithms are considered as one of the most efficient search techniques. Although they do not offer an optimal solution, their ability to reach a suitable solution in considerably short time gives them their respectable role in…

Neural and Evolutionary Computing · Computer Science 2014-01-22 Ayman M. Bahaa-Eldin , A. M. A. Wahdan , H. M. K. Mahdi

Generative molecular optimization aims to design molecules with properties surpassing those of existing compounds. However, such candidates are rare and expensive to evaluate, yielding sample efficiency essential. Additionally, surrogate…

A well-known pitfall of molecular generative models is that they are not guaranteed to generate synthesizable molecules. Existing solutions for this problem often struggle to effectively navigate exponentially large combinatorial space of…

Machine Learning · Computer Science 2026-01-13 Seul Lee , Karsten Kreis , Srimukh Prasad Veccham , Meng Liu , Danny Reidenbach , Saee Paliwal , Weili Nie , Arash Vahdat

Traditionally Genetic Algorithm has been used for optimization of unimodal and multimodal functions. Earlier researchers worked with constant probabilities of GA control operators like crossover, mutation etc. for tuning the optimization in…

Neural and Evolutionary Computing · Computer Science 2021-04-20 Avijit Basak

This paper implements a new way of solving a problem called the traveling salesman problem (TSP) using quantum genetic algorithm (QGA). We compared how well this new approach works to the traditional method known as a classical genetic…

Quantum Physics · Physics 2024-09-24 Yijiang Ma , Tan Chye Cheah

Significant research has been carried out recently to find the optimal path in network routing. Among them, the evolutionary algorithm approach is an area where work is carried out extensively. We in this paper have used particle swarm…

Networking and Internet Architecture · Computer Science 2014-07-22 Kavitha Sooda , T. R. Gopalakrishnan Nair

In multi-cloud environment, task scheduling has attracted a lot of attention due to NP-Complete nature of the problem. Moreover, it is very challenging due to heterogeneity of the cloud resources with varying capacities and functionalities.…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-30 Tripti Tanaya Tejaswi , Md Azharuddin , P. K. Jana

Exploration of complex high-dimensional spaces presents significant challenges in fields such as molecular discovery, process optimization, and supply chain management. Genetic Algorithms (GAs), while offering significant power for creating…

Machine Learning · Computer Science 2025-12-01 Mani Valleti , Aditya Raghavan , Sergei V. Kalinin

Generative artificial intelligence has revolutionized the exploration of chemical space, yet a critical bottleneck remains that a substantial fraction of generated molecules is synthetically inaccessible. Current solutions, such as post-hoc…

Artificial Intelligence · Computer Science 2025-12-24 Junren Li , Luhua Lai

Optimization of data placement in complex scientific workflows has become very crucial since the large amounts of data generated by these workflows significantly increases the turnaround time of the end-to-end application. It is almost…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-29 Dengpan Yin , Tevfik Kosar

The design of molecules and materials with tailored properties is challenging, as candidate molecules must satisfy multiple competing requirements that are often difficult to measure or compute. While molecular structures, produced through…

Chemical Physics · Physics 2023-02-07 Julia Westermayr , Joe Gilkes , Rhyan Barrett , Reinhard J. Maurer

An improved bilinear fuzzy genetic algorithm (BFGA) is introduced in this chapter for the design optimization of steel structures with semi-rigid connections. Semi-rigid connections provide a compromise between the stiffness of fully rigid…

Neural and Evolutionary Computing · Computer Science 2024-11-12 Salar Farahmand-Tabar , Payam Ashtari

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

Biological Physics · Physics 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

Context. Mathematical optimization can be used as a computational tool to obtain the optimal solution to a given problem in a systematic and efficient way. For example, in twice-differentiable functions and problems with no constraints, the…

Instrumentation and Methods for Astrophysics · Physics 2009-05-25 J. Canto , S. Curiel , E. Martinez-Gomez

Gaussian Probability Path based Generative Models (GPPGMs) generate data by reversing a stochastic process that progressively corrupts samples with Gaussian noise. Despite state-of-the-art results in 3D molecular generation, their…

Machine Learning · Computer Science 2026-02-23 Jingxiang Qu , Wenhan Gao , Ruichen Xu , Yi Liu

Computer networks are hard to manage. Given a set of high-level requirements (e.g., reachability, security), operators have to manually figure out the individual configuration of potentially hundreds of devices running complex distributed…

Networking and Internet Architecture · Computer Science 2017-05-31 Ahmed El-Hassany , Petar Tsankov , Laurent Vanbever , Martin Vechev

The choice of crossover and mutation strategies plays a crucial role in the searchability, convergence efficiency and precision of genetic algorithms. In this paper, a novel improved genetic algorithm is proposed by improving the crossover…

Neural and Evolutionary Computing · Computer Science 2022-10-12 Dingming Yang , Zeyu Yu , Hongqiang Yuan , Yanrong Cui

Here we propose an evolutionary algorithm that self modifies its operators at the same time that candidate solutions are evolved. This tackles convergence and lack of diversity issues, leading to better solutions. Operators are represented…

Neural and Evolutionary Computing · Computer Science 2017-12-19 Andres Felipe Cruz Salinas , Jonatan Gomez Perdomo

Genetic algorithm (GA) is an efficient tool for solving optimization problems by evolving solutions, as it mimics the Darwinian theory of natural evolution. The mutation operator is one of the key success factors in GA, as it is considered…

Neural and Evolutionary Computing · Computer Science 2018-01-23 Esra'a Alkafaween , Ahmad B. A. Hassanat
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