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This study investigates the current landscape and future directions of protein foundation model research. While recent advancements have transformed protein science and engineering, the field lacks a comprehensive benchmark for fair…

Biomolecules · Quantitative Biology 2025-06-19 Zhangyang Gao , Hao Wang , Cheng Tan , Chenrui Xu , Mengdi Liu , Bozhen Hu , Linlin Chao , Xiaoming Zhang , Stan Z. Li

Mammography and ultrasound are extensively used by radiologists as complementary modalities to achieve better performance in breast cancer diagnosis. However, existing computer-aided diagnosis (CAD) systems for the breast are generally…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Gavriel Habib , Nahum Kiryati , Miri Sklair-Levy , Anat Shalmon , Osnat Halshtok Neiman , Renata Faermann Weidenfeld , Yael Yagil , Eli Konen , Arnaldo Mayer

Some recent studies have described deep convolutional neural networks to diagnose breast cancer in mammograms with similar or even superior performance to that of human experts. One of the best techniques does two transfer learnings: the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Daniel G. P. Petrini , Carlos Shimizu , Rosimeire A. Roela , Gabriel V. Valente , Maria A. A. K. Folgueira , Hae Yong Kim

Medical images differ from natural images in significantly higher resolutions and smaller regions of interest. Because of these differences, neural network architectures that work well for natural images might not be applicable to medical…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Kangning Liu , Sudarshini Tyagi , Laura Heacock , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

The rapid advancement of foundation models in medical imaging represents a significant leap toward enhancing diagnostic accuracy and personalized treatment. However, the deployment of foundation models in healthcare necessitates a rigorous…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Congzhen Shi , Ryan Rezai , Jiaxi Yang , Qi Dou , Xiaoxiao Li

Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

Explainable AI (XAI) in medical histopathology is essential for enhancing the interpretability and clinical trustworthiness of deep learning models in cancer diagnosis. However, the black-box nature of these models often limits their…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H. Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

Vision impairment affects millions globally, and early detection is critical to preventing irreversible vision loss. Ophthalmology workflows require clinicians to integrate medical images, structured clinical data, and free-text notes to…

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

Foundation models refer to artificial intelligence (AI) models that are trained on massive amounts of data and demonstrate broad generalizability across various tasks with high accuracy. These models offer versatile, one-for-many or…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Rina Bao , Erfan Darzi , Sheng He , Chuan-Heng Hsiao , Mohammad Arafat Hussain , Jingpeng Li , Atle Bjornerud , Ellen Grant , Yangming Ou

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

The aim was to undertake a national survey of the setup of mammography imaging systems in the UK, we were particularly interested in image processing and software version. We created a program that can extract selected tags from the DICOM…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Alistair Mackenzie , John Loveland , Ruben van Engen

Visual foundation models (VFMs) have become increasingly popular due to their state-of-the-art performance. However, interpretability remains crucial for critical applications. In this sense, self-explainable models (SEM) aim to provide…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Hugues Turbé , Mina Bjelogrlic , Gianmarco Mengaldo , Christian Lovis

Mammography is crucial for breast cancer surveillance and early diagnosis. However, analyzing mammography images is a demanding task for radiologists, who often review hundreds of mammograms daily, leading to overdiagnosis and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Kun Zhao , Jakub Prokop , Javier Montalt Tordera , Sadegh Mohammadi

The advent of foundation models, particularly Vision-Language Models (VLMs) and Multi-modal Large Language Models (MLLMs), has redefined the frontiers of artificial intelligence, enabling remarkable generalization across diverse tasks with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Redwan Sony , Parisa Farmanifard , Hamzeh Alzwairy , Nitish Shukla , Arun Ross

Lesion detection is a fundamental problem in the computer-aided diagnosis scheme for mammography. The advance of deep learning techniques have made a remarkable progress for this task, provided that the training data are large and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Zheren Li , Zhiming Cui , Sheng Wang , Yuji Qi , Xi Ouyang , Qitian Chen , Yuezhi Yang , Zhong Xue , Dinggang Shen , Jie-Zhi Cheng

Mammography is often used as the most common laboratory method for the detection of breast cancer, yet associated with the high cost and many side effects. Machine learning prediction as an alternative method has shown promising results.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Sanaz Mojrian , Gergo Pinter , Javad Hassannataj Joloudari , Imre Felde , Narjes Nabipour , Laszlo Nadai , Amir Mosavi

While state-of-the-art models for breast cancer detection leverage multi-view mammograms for enhanced diagnostic accuracy, they often focus solely on visual mammography data. However, radiologists document valuable lesion descriptors that…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Gil Ben-Artzi , Feras Daragma , Shahar Mahpod
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