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Topology optimization (TO) is a common technique used in free-form designs. However, conventional TO-based design approaches suffer from high computational cost due to the need for repetitive forward calculations and/or sensitivity…

Artificial Intelligence · Computer Science 2020-09-15 Chao Qian , Wenjing Ye

In proton therapy of low-grade glioma (LGG) patients, contrast-enhancing brain lesions (CEBLs) on magnetic resonance imaging are considered predictive of late radiation-induced lesions. From the observation that CEBLs tend to concentrate in…

Medical Physics · Physics 2026-04-16 Tim Ortkamp , Habiba Sallem , Semi Harrabi , Martin Frank , Oliver Jäkel , Julia Bauer , Niklas Wahl

Efficient implementations of parallel applications on heterogeneous hybrid architectures require a careful balance between computations and communications with accelerator devices. Even if most of the communication time can be overlapped by…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-09-22 Raphaël Bleuse , Thierry Gautier , João V. F. Lima , Grégory Mounié , Denis Trystram

Personalized PageRank (PPR) is a graph algorithm that evaluates the importance of the surrounding nodes from a source node. Widely used in social network related applications such as recommender systems, PPR requires real-time responses…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-21 Lixiang Li , Yao Chen , Zacharie Zirnheld , Pan Li , Cong Hao

Geometric uncertainty can degrade treatment quality in radiation therapy. While margins and robust optimization mitigate these effects, they provide only implicit control over clinical goal fulfillment probability. We therefore develop a…

Medical Physics · Physics 2026-01-14 Albin Fredriksson , Erik Engwall , Jenneke de Jong , Johan Sundström

This paper presents a Graphics Processing Units (GPUs) acceleration method of an iterative scheme for gas-kinetic model equations. Unlike the previous GPU parallelization of explicit kinetic schemes, this work features a fast converging…

Computational Physics · Physics 2020-01-08 Lianhua Zhu , Peng Wang , Songze Chen , Zhaoli Guo , Yonghao Zhang

Dosage schedule of the Proton Pump Inhibitors (PPIs) is critical for gastric acid disorder treatment. In this paper, we develop a constrained optimization based approach for scheduling the PPIs dosage. In particular, we exploit a…

Systems and Control · Electrical Eng. & Systems 2023-04-10 Yutong Li , Nan Li , Anouck Girard , Ilya Kolmanovsky

Advances in ultra-intense laser technology have increased repetition rates and average power for chirped-pulse laser systems, which offers a promising solution for many applications including energetic proton sources. An important challenge…

Linear Programming (LP) is a foundational optimization technique with widespread applications in finance, energy trading, and supply chain logistics. However, traditional Central Processing Unit (CPU)-based LP solvers often struggle to meet…

Optimization and Control · Mathematics 2025-08-26 Xiyan Hu , Titus Parker , Connor Phillips , Yifa Yu

Correlation Plenoptic Imaging (CPI) is a novel technological imaging modality enabling to overcome drawbacks of standard plenoptic devices, while preserving their advantages. However, a major challenge in view of real-time application of…

Gradient Boosted Decision Tree (GBDT) is a widely-used machine learning algorithm that has been shown to achieve state-of-the-art results on many standard data science problems. We are interested in its application to multioutput problems…

Machine Learning · Computer Science 2022-11-24 Leonid Iosipoi , Anton Vakhrushev

We present a holistic design for GPU-accelerated computation in TrustZone TEE. Without pulling the complex GPU software stack into the TEE, we follow a simple approach: record the CPU/GPU interactions ahead of time, and replay the…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-11-08 Heejin Park , Felix Xiaozhu Lin

Nanodosimetry relates Ionization Detail (ID) and ionization parameters (Ip) to biological endpoints relevant for charged-particle radiotherapy. This supports a more physics-based modeling of biological effectiveness than traditional…

The NeuroEvolution of Augmenting Topologies (NEAT) algorithm has received considerable recognition in the field of neuroevolution. Its effectiveness is derived from initiating with simple networks and incrementally evolving both their…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Lishuang Wang , Mengfei Zhao , Enyu Liu , Kebin Sun , Ran Cheng

Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…

Medical Physics · Physics 2025-08-06 Hunter D. Ellis , Imteaz Rahaman , Apostoli Hillas , Botong Li , Vikren Sarkar , Kai Fu

Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…

Medical Physics · Physics 2025-07-30 M. A. McIntyre , J. Midson , P. Wilson , P Gorayski , C. E. Hsieh , S. W. Wu , E. Bezak

Last year, the official BitTorrent client switched to LEDBAT, a new congestion control algorithm targeting a lower-than Best Effort transport service. In this paper, we study this new protocol through packet-level simulations, with a…

Networking and Internet Architecture · Computer Science 2010-06-16 Giovanna Carofiglio , Luca Muscariello , Dario Rossi , Claudio Testa

We investigated the imaging performance of a fast convergent ordered-subsets algorithm with subiteration-dependent preconditioners (SDPs) for positron emission tomography (PET) image reconstruction. In particular, we considered the use of…

Numerical Analysis · Mathematics 2022-06-09 Jianfeng Guo , C. Ross Schmidtlein , Andrzej Krol , Si Li , Yizun Lin , Sangtae Ahn , Charles Stearns , Yuesheng Xu

Machine-learned interatomic potentials have revolutionized molecular dynamics simulations by providing quantum-mechanical accuracy at empirical-potential speeds. The graphics processing unit molecular dynamics (GPUMD) package, featuring the…

We present a GPU-accelerated cosmological simulation code, PhotoNs-GPU, based on algorithm of Particle Mesh Fast Multipole Method (PM-FMM), and focus on the GPU utilization and optimization. A proper interpolated method for truncated…

Instrumentation and Methods for Astrophysics · Physics 2021-12-28 Qiao Wang , Chen Meng
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