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A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

The automation of chest X-ray reporting has garnered significant interest due to the time-consuming nature of the task. However, the clinical accuracy of free-text reports has proven challenging to quantify using natural language processing…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Matthias Keicher , Kamilia Zaripova , Tobias Czempiel , Kristina Mach , Ashkan Khakzar , Nassir Navab

The chest X-ray (CXR) is commonly employed to diagnose thoracic illnesses, but the challenge of achieving accurate automatic diagnosis through this method persists due to the complex relationship between pathology. In recent years, various…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Weizhi Nie , Chen Zhang , Dan song , Yunpeng Bai , Keliang Xie , Anan Liu

Chest X-rays (CXR) are essential for diagnosing a variety of conditions, but when used on new populations, model generalizability issues limit their efficacy. Generative AI, particularly denoising diffusion probabilistic models (DDPMs),…

Medical images commonly exhibit multiple abnormalities. Predicting them requires multi-class classifiers whose training and desired reliable performance can be affected by a combination of factors, such as, dataset size, data source,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Sameer Antani

Lung segmentation in chest X-rays (CXRs) is an important prerequisite for improving the specificity of diagnoses of cardiopulmonary diseases in a clinical decision support system. Current deep learning models for lung segmentation are…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Sivaramakrishnan Rajaraman , Feng Yang , Ghada Zamzmi , Zhiyun Xue , Sameer Antani

Radiologists face high burnout rates, partially due to the increasing volume of Chest X-rays (CXRs) requiring interpretation and reporting. Automated CXR report generation holds promise for reducing this burden and improving patient care.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Aaron Nicolson , Jason Dowling , Bevan Koopman

Existing deep learning models for chest radiology often neglect patient metadata, limiting diagnostic accuracy and fairness. To bridge this gap, we introduce MetaCheX, a novel multimodal framework that integrates chest X-ray images with…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Nathan He , Cody Chen

Methods that address data shifts usually assume full access to multiple datasets. In the healthcare domain, however, privacy-preserving regulations as well as commercial interests limit data availability and, as a result, researchers can…

Machine Learning · Statistics 2022-05-03 Tal El-Hay , Chen Yanover

The absence of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. Although various methods of explainable artificial intelligence (XAI) have been suggested, there is a lack of literature that…

Machine Learning · Computer Science 2023-06-22 Aida Brankovic , David Cook , Jessica Rahman , Wenjie Huang , Sankalp Khanna

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

A global shortage of radiologists has been exacerbated by the significant volume of chest X-ray workloads, particularly in primary care. Although multimodal large language models show promise, existing evaluations predominantly rely on…

Foundation Models (FMs) trained on Electronic Health Records (EHRs) have achieved state-of-the-art results on numerous clinical prediction tasks. However, most existing EHR FMs have context windows of <1k tokens. This prevents them from…

Chest imaging plays an essential role in diagnosing and predicting patients with COVID-19 with evidence of worsening respiratory status. Many deep learning-based approaches for pneumonia recognition have been developed to enable…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Shengchao Chen , Sufen Ren , Guanjun Wang , Mengxing Huang , Chenyang Xue

Human visual attention has recently shown its distinct capability in boosting machine learning models. However, studies that aim to facilitate medical tasks with human visual attention are still scarce. To support the use of visual…

Image and Video Processing · Electrical Eng. & Systems 2022-02-16 Hongzhi Zhu , Robert Rohling , Septimiu Salcudean

Deep learning models for image classification are often trained at a resolution of 224 x 224 pixels for historical and efficiency reasons. However, chest X-rays are acquired at a much higher resolution to display subtle pathologies. This…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Alessandro Wollek , Sardi Hyska , Bastian Sabel , Michael Ingrisch , Tobias Lasser

This study investigates the integration of diverse patient data sources into multimodal language models for automated chest X-ray (CXR) report generation. Traditionally, CXR report generation relies solely on CXR images and limited…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Aaron Nicolson , Shengyao Zhuang , Jason Dowling , Bevan Koopman

We propose a data collecting and annotation pipeline that extracts information from Vietnamese radiology reports to provide accurate labels for chest X-ray (CXR) images. This can benefit Vietnamese radiologists and clinicians by annotating…

Image and Video Processing · Electrical Eng. & Systems 2023-01-11 Thao T. B. Nguyen , Tam M. Vo , Thang V. Nguyen , Hieu H. Pham , Ha Q. Nguyen

Objective: The objective of this study is to develop a machine learning (ML)-based framework for early risk stratification of clinical trials (CTs) according to their likelihood of exhibiting a high rate of dosing errors, using information…

Machine Learning · Computer Science 2026-02-27 Félicien Hêche , Sohrab Ferdowsi , Anthony Yazdani , Sara Sansaloni-Pastor , Douglas Teodoro

Chest X-rays (CXRs) are among the most frequently performed imaging examinations worldwide, yet rising imaging volumes increase radiologist workload and the risk of diagnostic errors. Although artificial intelligence (AI) systems have shown…

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