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High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu

Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult especially for small particles with low contrast. As…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Ayelet Heimowitz , Joakim Andén , Amit Singer

Many parameter estimation problems arising in applications are best cast in the framework of Bayesian inversion. This allows not only for an estimate of the parameters, but also for the quantification of uncertainties in the estimates.…

Computation · Statistics 2020-10-28 Emmet Cleary , Alfredo Garbuno-Inigo , Shiwei Lan , Tapio Schneider , Andrew M Stuart

The electrocardiogram (ECG) is a vital tool for diagnosing heart diseases. However, many disease patterns are derived from outdated datasets and traditional stepwise algorithms with limited accuracy. This study presents a method for direct…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Oğuzhan Büyüksolak , İlkay Öksüz

Bayesian graphical models are a useful tool for understanding dependence relationships among many variables, particularly in situations with external prior information. In high-dimensional settings, the space of possible graphs becomes…

Machine Learning · Statistics 2019-02-07 Zehang Richard Li , Tyler H. McCormick

Electrocardiography (ECG) is the clinical gold standard for cardiovascular disease (CVD) assessment, yet continuous monitoring is constrained by the need for dedicated hardware and trained personnel. Photoplethysmography (PPG) is ubiquitous…

Machine Learning · Computer Science 2026-01-22 Xiaocheng Fang , Jiarui Jin , Haoyu Wang , Che Liu , Jieyi Cai , Yujie Xiao , Guangkun Nie , Bo Liu , Shun Huang , Hongyan Li , Shenda Hong

Background: Conventional electrocardiogram (ECG) analysis faces a persistent dichotomy: expert-driven features ensure interpretability but lack sensitivity to latent patterns, while deep learning offers high accuracy but functions as a…

Quantitative Methods · Quantitative Biology 2026-01-23 Deyun Zhang , Jun Li , Shijia Geng , Yue Wang , Shijie Chen , Sumei Fan , Qinghao Zha , Shenda Hong

Cardiovascular disease is a major life-threatening condition that is commonly monitored using electrocardiogram (ECG) signals. However, these signals are often contaminated by various types of noise at different intensities, significantly…

Signal Processing · Electrical Eng. & Systems 2024-07-17 Ding Zhu , Vishnu Kabir Chhabra , Mohammad Mahdi Khalili

Electrocardiogram (ECG) analysis is a fundamental tool for diagnosing cardiovascular conditions, yet anomaly detection in ECG signals remains challenging due to their inherent complexity and variability. We propose Multi-scale Masked…

Machine Learning · Computer Science 2025-02-11 Ya Zhou , Yujie Yang , Jianhuang Gan , Xiangjie Li , Jing Yuan , Wei Zhao

For particle filters and ensemble Kalman filters it is of practical importance to understand how and why data assimilation methods can be effective when used with a fixed small number of particles, since for many large-scale applications it…

Probability · Mathematics 2018-11-06 David Kelly , Andrew M Stuart

Electromyogram (EMG) has been utilized to interface signals for prosthetic hands and information devices owing to its ability to reflect human motion intentions. Although various EMG classification methods have been introduced into…

Signal Processing · Electrical Eng. & Systems 2021-08-11 Akira Furui , Takuya Igaue , Toshio Tsuji

"Particle methods" are sequential Monte Carlo algorithms, typically involving importance sampling, that are used to estimate and sample from joint and marginal densities from a collection of a, presumably increasing, number of random…

Computation · Statistics 2014-07-17 J. N. Corcoran , D. Jennings

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, and its clinical assessment requires accurate characterization of atrial electrical activity. Noninvasive electrocardiographic imaging (ECGI) combined with deep…

Cardiovascular diseases are the leading cause of death and disability in the world and thus their detection is extremely important as early as possible so that it can be prognosed and managed appropriately. Hence, electrophysiological…

Medical Physics · Physics 2024-03-07 Sourav Chowdhury , Apratim Ghosal , Suparna Roychowhury , Indranath Chaudhuri

We introduce a modified algorithm to perform nonlinear filtering of a time series by locally linear phase space projections. Unlike previous implementations, the algorithm can be used not only for a posteriori processing but includes the…

chao-dyn · Physics 2015-06-24 Thomas Schreiber , Marcus Richter

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

We present an imaging algorithm for polarimetric interferometric data from radio telescopes. It is based on Bayesian statistics and thereby able to provide uncertainties and to incorporate prior information such as positivity of the total…

Instrumentation and Methods for Astrophysics · Physics 2025-04-02 Philipp Arras , Jakob Roth , Martin Reinecke , Richard A. Perley , Andrei Frolov , Rüdiger Westermann , Torsten A. Enßlin

Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

Aims. To investigate the performance of a deconvolution map-making algorithm for an experiment with a circular scanning strategy, specifically in this case for the analysis of Planck data, and to quantify the effects of making maps using…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 D. L. Harrison , F. van Leeuwen , M. A. J. Ashdown

We present a new approach to the electromagnetic inverse problem that explicitly addresses the ambiguity associated with its ill-posed character. Rather than calculating a single ``best'' solution according to some criterion, our approach…

Neurons and Cognition · Quantitative Biology 2007-05-23 David M. Schmidt , John S. George , C. C. Wood