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The successful adaptation of foundation models to multi-modal medical imaging is a critical yet unresolved challenge. Existing models often struggle to effectively fuse information from multiple sources and adapt to the heterogeneous nature…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shadi Alijani , Fereshteh Aghaee Meibodi , Homayoun Najjaran

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin

Combining images from multi-modalities is beneficial to explore various information in computer vision, especially in the medical domain. As an essential part of clinical diagnosis, multi-modal brain tumor segmentation aims to delineate the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Zhongzhen Huang , Linda Wei , Shaoting Zhang , Xiaofan Zhang

Accurate lesion segmentation in ultrasound images is essential for preventive screening and clinical diagnosis, yet remains challenging due to low contrast, blurry boundaries, and significant scale variations. Although existing deep…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Chen Wang , Yixin Zhu , Yongbin Zhu , Fengyuan Shi , Qi Li , Jun Wang , Zuozhu Liu , Keli Hu

In this paper, we develop a two-stage neural network solution for the challenging task of white-matter lesion segmentation. To cope with the vast vari- ability in lesion sizes, we sample brain MR scans with patches at three differ- ent…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Zhewei Wang , Charles D. Smith , Jundong Liu

Automated fetal head segmentation in ultrasound images is critical for accurate biometric measurements in prenatal care. While existing deep learning approaches have achieved a reasonable performance, they struggle with issues like low…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Ammar Bhilwarawala , Mainak Bandyopadhyay

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Magnetic resonance imaging (MRI) is routinely used for brain tumor diagnosis, treatment planning, and post-treatment surveillance. Recently, various models based on deep neural networks have been proposed for the pixel-level segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Daniel E. Cahall , Ghulam Rasool , Nidhal C. Bouaynaya , Hassan M. Fathallah-Shaykh

U-Net is widely used in medical image segmentation due to its simple and flexible architecture design. To address the challenges of scale and complexity in medical tasks, several variants of U-Net have been proposed. In particular, methods…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Weibin Yang , Zhiqi Dong , Mingyuan Xu , Longwei Xu , Dehua Geng , Yusong Li , Pengwei Wang

For brain tumour segmentation, deep learning models can achieve human expert-level performance given a large amount of data and pixel-level annotations. However, the expensive exercise of obtaining pixel-level annotations for large amounts…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xiao Liu , Antanas Kascenas , Hannah Watson , Sotirios A. Tsaftaris , Alison Q. O'Neil

Magnetic Resonance Imaging (MRI) plays a crucial role in MRI-guided adaptive radiotherapy for head and neck cancer (HNC) due to its superior soft-tissue contrast. However, accurately segmenting the gross tumor volume (GTV), which includes…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Jintao Ren , Kim Hochreuter , Jesper Folsted Kallehauge , Stine Sofia Korreman

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Cheng Chen , Qi Dou , Yueming Jin , Hao Chen , Jing Qin , Pheng-Ann Heng

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Mobarakol Islam , Hongliang Ren

Despite continuous advancements in cancer treatment, brain metastatic disease remains a significant complication of primary cancer and is associated with an unfavorable prognosis. One approach for improving diagnosis, management, and…

Other Quantitative Biology · Quantitative Biology 2025-07-11 Nazanin Maleki , Raisa Amiruddin , Ahmed W. Moawad , Nikolay Yordanov , Athanasios Gkampenis , Pascal Fehringer , Fabian Umeh , Crystal Chukwurah , Fatima Memon , Bojan Petrovic , Justin Cramer , Mark Krycia , Elizabeth B. Shrickel , Ichiro Ikuta , Gerard Thompson , Lorenna Vidal , Vilma Kosovic , Adam E. Goldman-Yassen , Virginia Hill , Tiffany So , Sedra Mhana , Albara Alotaibi , Nathan Page , Prisha Bhatia , Melisa S. Guelen , Yasaman Sharifi , Marko Jakovljevic , Salma Abosabie , Sara Abosabie , Mohanad Ghonim , Mohamed Ghonim , Amirreza Manteghinejad , Anastasia Janas , Kiril Krantchev , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Sanjay Aneja , Syed Muhammad Anwar , Timothy Bergquist , Veronica Chiang , Verena Chung , Gian Marco Conte , Farouk Dako , James Eddy , Ivan Ezhov , Nastaran Khalili , Keyvan Farahani , Juan Eugenio Iglesias , Zhifan Jiang , Elaine Johanson , Anahita Fathi Kazerooni , Florian Kofler , Dominic LaBella , Koen Van Leemput , Hongwei Bran Li , Marius George Linguraru , Xinyang Liu , Zeke Meier , Bjoern H Menze , Harrison Moy , Klara Osenberg , Marie Piraud , Zachary Reitman , Russell Takeshi Shinohara , Chunhao Wang , Benedikt Wiestler , Walter Wiggins , Umber Shafique , Klara Willms , Arman Avesta , Khaled Bousabarah , Satrajit Chakrabarty , Nicolo Gennaro , Wolfgang Holler , Manpreet Kaur , Pamela LaMontagne , MingDe Lin , Jan Lost , Daniel S. Marcus , Ryan Maresca , Sarah Merkaj , Gabriel Cassinelli Pedersen , Marc von Reppert , Aristeidis Sotiras , Oleg Teytelboym , Niklas Tillmans , Malte Westerhoff , Ayda Youssef , Devon Godfrey , Scott Floyd , Andreas Rauschecker , Javier Villanueva-Meyer , Irada Pflüger , Jaeyoung Cho , Martin Bendszus , Gianluca Brugnara , Gloria J. Guzman Perez-Carillo , Derek R. Johnson , Anthony Kam , Benjamin Yin Ming Kwan , Lillian Lai , Neil U. Lall , Satya Narayana Patro , Lei Wu , Anu Bansal , Frederik Barkhof , Cristina Besada , Sammy Chu , Jason Druzgal , Alexandru Dusoi , Luciano Farage , Fabricio Feltrin , Amy Fong , Steve H. Fung , R. Ian Gray , Michael Iv , Alida A. Postma , Amit Mahajan , David Joyner , Chase Krumpelman , Laurent Letourneau-Guillon , Christie M. Lincoln , Mate E. Maros , Elka Miller , Fanny Morón , Esther A. Nimchinsky , Ozkan Ozsarlak , Uresh Patel , Saurabh Rohatgi , Atin Saha , Anousheh Sayah , Eric D. Schwartz , Robert Shih , Mark S. Shiroishi , Juan E. Small , Manoj Tanwar , Jewels Valerie , Brent D. Weinberg , Matthew L. White , Robert Young , Vahe M. Zohrabian , Aynur Azizova , Melanie Maria Theresa Brüßeler , Abdullah Okar , Luca Pasquini , Yasaman Sharifi , Gagandeep Singh , Nico Sollmann , Theodora Soumala , Mahsa Taherzadeh , Philipp Vollmuth , Martha Foltyn-Dumitru , Ajay Malhotra , Francesco Dellepiane , Víctor M. Pérez-García , Hesham Elhalawani , Maria Correia de Verdier , Sanaria Al Rubaiey , Rui Duarte Armindo , Kholod Ashraf , Moamen M. Asla , Mohamed Badawy , Jeroen Bisschop , Nima Broomand Lomer , Jan Bukatz , Jim Chen , Petra Cimflova , Felix Corr , Alexis Crawley , Lisa Deptula , Tasneem Elakhdar , Islam H. Shawali , Shahriar Faghani , Alexandra Frick , Vaibhav Gulati , Muhammad Ammar Haider , Fátima Hierro , Rasmus Holmboe Dahl , Sarah Maria Jacobs , Kuang-chun Jim Hsieh , Sedat G. Kandemirli , Katharina Kersting , Laura Kida , Sofia Kollia , Ioannis Koukoulithras , Xiao Li , Ahmed Abouelatta , Aya Mansour , Ruxandra-Catrinel Maria-Zamfirescu , Marcela Marsiglia , Yohana Sarahi Mateo-Camacho , Mark McArthur , Olivia McDonnel , Maire McHugh , Mana Moassefi , Samah Mostafa Morsi , Alexander Munteanu , Khanak K. Nandolia , Syed Raza Naqvi , Yalda Nikanpour , Mostafa Alnoury , Abdullah Mohamed Aly Nouh , Francesca Pappafava , Markand D. Patel , Samantha Petrucci , Eric Rawie , Scott Raymond , Borna Roohani , Sadeq Sabouhi , Laura M. Sanchez Garcia , Zoe Shaked , Pokhraj P. Suthar , Talissa Altes , Edvin Isufi , Yaseen Dhemesh , Jaime Gass , Jonathan Thacker , Abdul Rahman Tarabishy , Benjamin Turner , Sebastiano Vacca , George K. Vilanilam , Daniel Warren , David Weiss , Fikadu Worede , Sara Yousry , Wondwossen Lerebo , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Katherine E. Link , Evan Calabrese , Nourel Hoda Tahon , Ayman Nada , Jeffrey D. Rudie , Janet Reid , Kassa Darge , Aly H. Abayazeed , Philipp Lohmann , Yuri S. Velichko , Spyridon Bakas , Mariam Aboian

Accurate segmentation of glioma brain tumors is crucial for diagnosis and treatment planning. Deep learning techniques offer promising solutions, but optimal model architectures remain under investigation. We used the BraTS 2021 dataset,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Farzan Moodi , Fereshteh Khodadadi Shoushtari , Gelareh Valizadeh , Dornaz Mazinani , Hanieh Mobarak Salari , Hamidreza Saligheh Rad

Background: Brain tumor segmentation requires precise delineation of hierarchical structures from multi-sequence MRI. However, existing deep learning methods primarily rely on visual features, showing insufficient discriminative power in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Mingda Zhang , Kaiwen Pan

The 2024 Brain Tumor Segmentation Meningioma Radiotherapy (BraTS-MEN-RT) challenge aimed to advance automated segmentation algorithms using the largest known multi-institutional dataset of 750 radiotherapy planning brain MRIs with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Dominic LaBella , Valeriia Abramova , Mehdi Astaraki , Andre Ferreira , Zhifan Jiang , Mason C. Cleveland , Ramandeep Kang , Uma M. Lal-Trehan Estrada , Cansu Yalcin , Rachika E. Hamadache , Clara Lisazo , Adrià Casamitjana , Joaquim Salvi , Arnau Oliver , Xavier Lladó , Iuliana Toma-Dasu , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger , Daniel Capellán-Martín , Abhijeet Parida , Austin Tapp , Xinyang Liu , Maria J. Ledesma-Carbayo , Jay B. Patel , Thomas N. McNeal , Maya Viera , Owen McCall , Albert E. Kim , Elizabeth R. Gerstner , Christopher P. Bridge , Katherine Schumacher , Michael Mix , Kevin Leu , Shan McBurney-Lin , Pierre Nedelec , Javier Villanueva-Meyer , David R. Raleigh , Jonathan Shapey , Tom Vercauteren , Kazumi Chia , Marina Ivory , Theodore Barfoot , Omar Al-Salihi , Justin Leu , Lia M. Halasz , Yuri S. Velichko , Chunhao Wang , John P. Kirkpatrick , Scott R. Floyd , Zachary J. Reitman , Trey C. Mullikin , Eugene J. Vaios , Christina Huang , Ulas Bagci , Sean Sachdev , Jona A. Hattangadi-Gluth , Tyler M. Seibert , Nikdokht Farid , Connor Puett , Matthew W. Pease , Kevin Shiue , Syed Muhammad Anwar , Shahriar Faghani , Peter Taylor , Pranav Warman , Jake Albrecht , András Jakab , Mana Moassefi , Verena Chung , Rong Chai , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Nazanin Maleki , Rachit Saluja , Florian Kofler , Christopher G. Schwarz , Philipp Lohmann , Phillipp Vollmuth , Louis Gagnon , Maruf Adewole , Hongwei Bran Li , Anahita Fathi Kazerooni , Nourel Hoda Tahon , Udunna Anazodo , Ahmed W. Moawad , Bjoern Menze , Marius George Linguraru , Mariam Aboian , Benedikt Wiestler , Ujjwal Baid , Gian-Marco Conte , Andreas M. Rauschecker , Ayman Nada , Aly H. Abayazeed , Raymond Huang , Maria Correia de Verdier , Jeffrey D. Rudie , Spyridon Bakas , Evan Calabrese

In this study, we proposed and validated a multi-atlas guided 3D fully convolutional network (FCN) ensemble model (M-FCN) for segmenting brain regions of interest (ROIs) from structural magnetic resonance images (MRIs). One major limitation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiong Wu , Xiaoying Tang
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