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Olfaction lies at the intersection of chemical structure, neural encoding, and linguistic perception, yet existing representation methods fail to fully capture this pathway. Current approaches typically model only isolated segments of the…

Computation and Language · Computer Science 2026-04-21 Yanyi Su , Hongshuai Wang , Zhifeng Gao , Jun Cheng

Endoscopy plays a major role in identifying any underlying abnormalities within the gastrointestinal (GI) tract. There are multiple GI tract diseases that are life-threatening, such as precancerous lesions and other intestinal cancers. In…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Harshala Gammulle , Yubo Chen , Sridha Sridharan , Travis Klein , Clinton Fookes

We study the learning of an external signal by a neural network and the time to forget it when this network is submitted to noise. The presentation of an external stimulus to the recurrent network of binary neurons may change the state of…

Probability · Mathematics 2020-06-11 Pascal Helson

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

Neurons and Cognition · Quantitative Biology 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Analyzing the brain in terms of organizational structures at intermediate scales provides an approach to negotiate the complexity arising from interactions between its large number of components. Focusing on a wiring diagram that spans the…

Neurons and Cognition · Quantitative Biology 2023-01-10 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Molecular odor prediction has great potential across diverse fields such as chemistry, pharmaceuticals, and environmental science, enabling the rapid design of new materials and enhancing environmental monitoring. However, current methods…

Machine Learning · Computer Science 2025-02-04 HongXin Xie , JianDe Sun , Yi Shao , Shuai Li , Sujuan Hou , YuLong Sun , Yuxiang Liu

Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…

Molecular Networks · Quantitative Biology 2017-08-02 Tahir Yusufaly , James Q. Boedicker

This study explores how the selection of neuron models and learning rules impacts the classification performance of Spiking Neural Networks (SNNs), with a focus on applications in bio-signal processing. We compare biologically inspired…

Neurons and Cognition · Quantitative Biology 2025-09-10 Zofia Rudnicka , Janusz Szczepanski , Agnieszka Pregowska

Multifunctionality describes the capacity for a neural network to perform multiple mutually exclusive tasks without altering its network connections; and is an emerging area of interest in the reservoir computing machine learning paradigm.…

Machine Learning · Computer Science 2023-06-06 Jacob Morra , Andrew Flynn , Andreas Amann , Mark Daley

Artificial neural networks for motor control usually adopt generic architectures like fully connected MLPs. While general, these tabula rasa architectures rely on large amounts of experience to learn, are not easily transferable to new…

Machine Learning · Computer Science 2022-11-29 Nikhil X. Bhattasali , Anthony M. Zador , Tatiana A. Engel

Biological genotypes do not code directly for phenotypes; developmental physiology is the control layer that separates genomes from capacities ascertained by selection. A key aspect is competency, as cells are not a passive material but…

Populations and Evolution · Quantitative Biology 2022-08-01 Lakshwin Shreesha , Michael Levin

We investigate the use of modularity as a quantifier of whole-brain functional networks. Brain networks are constructed from functional magnetic resonance imaging while subjects listened to auditory pieces that varied in emotivity and…

Neurons and Cognition · Quantitative Biology 2020-09-23 Melia E. Bonomo , Christof Karmonik , Anthony K. Brandt , J. Todd Frazier

How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely…

Neurons and Cognition · Quantitative Biology 2023-12-12 Julian Rossbroich , Friedemann Zenke

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on many visual tasks. Recently, they became useful models for the visual system in neuroscience. However, it is still not clear what are learned by CNNs in…

Neurons and Cognition · Quantitative Biology 2020-02-19 Qi Yan , Yajing Zheng , Shanshan Jia , Yichen Zhang , Zhaofei Yu , Feng Chen , Yonghong Tian , Tiejun Huang , Jian K. Liu

To assist researchers to identify Environmental Microorganisms (EMs) effectively, a Multiscale CNN-CRF (MSCC) framework for the EM image segmentation is proposed in this paper. There are two parts in this framework: The first is a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Jinghua Zhang , Chen Li , Frank Kulwa , Xin Zhao , Changhao Sun , Zihan Li , Tao Jiang , Hong Li , Shouliang Qi

Animal behavior and neural recordings show that the brain is able to measure both the intensity of an odor and the timing of odor encounters. However, whether intensity or timing of odor detections is more informative for olfactory-driven…

Quantitative Methods · Quantitative Biology 2021-06-17 Nicola Rigolli , Nicodemo Magnoli , Lorenzo Rosasco , Agnese Seminara

Through natural evolution, nervous systems of organisms formed near-optimal structures to express behavior. Here, we propose an effective way to create control agents, by \textit{re-purposing} the function of biological neural circuit…

Neural and Evolutionary Computing · Computer Science 2017-11-10 Mathias Lechner , Radu Grosu , Ramin M. Hasani

In this study, we explore how the combination of synthetic biology, neuroscience modeling, and neuromorphic electronic systems offers a new approach to creating an artificial system that mimics the natural sense of smell. We argue that a…

Neural and Evolutionary Computing · Computer Science 2025-08-04 Kevin Max , Larissa Sames , Shimeng Ye , Jan Steinkühler , Federico Corradi

How can we build agents that keep learning from experience, quickly and efficiently, after their initial training? Here we take inspiration from the main mechanism of learning in biological brains: synaptic plasticity, carefully tuned by…

Neural and Evolutionary Computing · Computer Science 2018-08-01 Thomas Miconi , Jeff Clune , Kenneth O. Stanley