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Histological visualizations are critical to clinical disease management and are fundamental to biological understanding. However, current approaches that rely on bright-field microscopy require extensive tissue preparation prior to imaging.…

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

In Photoacoustic imaging (PAI), the most prevalent beamforming algorithm is delay-and-sum (DAS) due to its simple implementation. However, it results in a low quality image affected by the high level of sidelobes. Coherence factor (CF) can…

Signal Processing · Electrical Eng. & Systems 2017-10-10 Moein Mozaffarzadeh , Mohammad Mehrmohammadi , Bahador Makkiabadi

While passive acoustic mapping (PAM) has been advanced for monitoring acoustic cavitation activity in focused ultrasound (FUS) therapy, achieving both real-time and high-quality imaging capabilities is still challenging. The angular…

Medical Physics · Physics 2024-12-04 Yi Zeng , Hui Zhu , Jinwei Li , Jianfeng Li , Fei Li , Shukuan Lu , Xiran Cai

Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

In recent years, neural networks have been used to solve phase retrieval problems in imaging with superior accuracy and speed than traditional techniques, especially in the presence of noise. However, in the context of interferometric…

Far-field optical imaging inevitably involves low-pass spatial filtering, limiting the resolution. Moreover, conventional imaging suppresses high spatial frequency components close to the cutoff, making them invisible under noise,…

Quantum Physics · Physics 2026-05-08 Li Gong , Aonan Zhang , Madhura Ghosh Dastidar , Alexander Duplinskii , A. I. Lvovsky

Ptychography, as a powerful lensless imaging method, has become a popular member of the coherent diffractive imaging family over decades of development. The ability to utilize low-dose X-rays and/or fast scans offers a big advantage in a…

Medical Physics · Physics 2024-06-14 Longlong Wu , Shinjae Yoo , Yong S. Chu , Xiaojing Huang , Ian K. Robinson

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Coherent diffractive imaging (CDI) provides new opportunities for high resolution X-ray imaging with simultaneous amplitude and phase contrast. Extensions to CDI broaden the scope of the technique for use in a wide variety of experimental…

Optics · Physics 2016-01-20 Matthew H. Seaberg , Alexandre d'Aspremont , Joshua J. Turner

The demand for high-quality medical imaging in clinical practice and assisted diagnosis has made 3D image reconstruction in radiological imaging a key research focus. Artificial intelligence (AI) has emerged as a promising approach for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Yuezhe Yang , Lei Bi , Boyu Yang , Yaqian Wang , Yang He , Yige Peng , Zhe Jin , Xingbo Dong , Jinman Kim

Ultrasonic phased array technology, while versatile, often requires complex computing resources and numerous amplifier components. We present a Manually Reconfigurable Phased Array that physically controls transducer position and phase,…

Applied Physics · Physics 2025-05-22 Soma Mochizuki , Yoichi Ochiai , Tatsuki Fushimi

The correction of the aberration of transcranial focused ultrasounds is a relevant issue for enhancing various non-invasive medical treatments. Emission through multi-element phased arrays has been the most widely accepted method to reduce…

Medical Physics · Physics 2018-05-28 Marcelino Ferri , JM Bravo , Javier Redondo , JV Sánchez-Pérez

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Photoacoustic imaging (PAI) uniquely combines optical contrast with the penetration depth of ultrasound, making it critical for clinical applications. However, the quality of 3D PAI is often degraded due to reconstruction artifacts caused…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Shuang Li , Qian Chen , Chulhong Kim , Seongwook Choi , Yibing Wang , Yu Zhang , Changhui Li

Ultrasound imaging faces a trade-off between image quality and hardware complexity caused by dense transducers. Sparse arrays are one popular solution to mitigate this challenge. This work proposes an end-to-end optimization framework that…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Sergio Urrea , Adrian Basarab , Hervé Liebgott , Henry Arguello

Spectroscopic photoacoustic (sPA) imaging uses multiple wavelengths to differentiate chromophores based on their unique optical absorption spectra. This technique has been widely applied in areas such as vascular mapping, tumor detection,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Fangzhou Lin , Shang Gao , Yichuan Tang , Xihan Ma , Ryo Murakami , Ziming Zhang , John D. Obayemi , Winston W. Soboyejo , Haichong K. Zhang

Quantitative phase imaging (QPI) is a label-free computational imaging technique used in various fields, including biology and medical research. Modern QPI systems typically rely on digital processing using iterative algorithms for phase…

Optics · Physics 2023-06-28 Yuhang Li , Yi Luo , Deniz Mengu , Bijie Bai , Aydogan Ozcan

Medical image synthesis has become an essential strategy for augmenting datasets and improving model generalization in data-scarce clinical settings. However, fine-grained and controllable synthesis remains difficult due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Shuhan Ding , Jingjing Fu , Yu Gu , Naiteek Sangani , Mu Wei , Paul Vozila , Nan Liu , Jiang Bian , Hoifung Poon

Phased array antennas (PAAs) possessing broadband beamforming capabilities are crucial for advanced radar and wireless communication systems. Nevertheless, traditional phase-shifter-based PAA beamformers frequently encounter the beam-squint…

Optics · Physics 2025-02-14 Mian Wang , Wenxin Zhang , Zeyu Ren , Shangyuan Li , Xiaoping Zheng , Xiaoxiao Xue
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