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Related papers: On a Neutral Host-Virus Model with Recombination

200 papers

The paper continues the study of the phenomenon of local immunodeficiency (LI) in viral cross-immunoreactivity networks, with a focus on the roles and interactions between altruistic and persistent viral variants. As always, only the state…

Populations and Evolution · Quantitative Biology 2024-05-29 Leonid Bunimovich , Athulya Ram

A model describing the dynamics related to the spreading of non-lethal infectious diseases in a fixed-size population is proposed. The model consists of a non-linear delay-differential equation describing the time evolution of the increment…

Populations and Evolution · Quantitative Biology 2010-10-05 A. Noviello , F. Romeo , R. De Luca

Host-to-host variability with respect to interactions between microorganisms and multicellular hosts are commonly observed in infection and in homeostasis. However, the majority of mechanistic models used in analyzing host-microorganism…

Populations and Evolution · Quantitative Biology 2015-06-19 Sayak Mukherjee , Kristin E. Weimer , Sang-Cheol Seok , Will C. Ray , C. Jayaprakash , Veronica J. Vieland , W. Edward Swords , Jayajit Das

The host immune response can often efficiently suppress a virus infection, which may lead to selection for immune-resistant viral variants within the host. For example, during HIV infection, an array of CTL immune response populations…

Populations and Evolution · Quantitative Biology 2018-02-23 Cameron J. Browne , Hal L. Smith

We extend the spatial $\Lambda$-Fleming-Viot process introduced in [Electron. J. Probab. 15 (2010) 162-216] to incorporate recombination. The process models allele frequencies in a population which is distributed over the two-dimensional…

Probability · Mathematics 2012-11-28 A. M. Etheridge , A. Véber

We study a model for the spread of an infectious disease which incorporates spatial and temporal effects. The model is a delayed multi-type branching process in which types represent geographic regions while infected individuals reproduce…

Probability · Mathematics 2023-01-27 Andrew Hart , Servet Martínez

We propose a nonlocal epidemic model whose spatial domain evolves over time and is represented by $[0,h(t)]$ with $h(t)$ standing for the spreading front of epidemic. It is assumed that the agents can cross the fixed boundary $x=0$, but…

Analysis of PDEs · Mathematics 2024-08-15 Xueping Li , Lei Li

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

Diseases emerge, persist and vanish in an ongoing battle for available hosts. Hosts, on the other hand, defend themselves by developing immunity that limits the ability of pathogens to reinfect them. We here explore a multi-disease system…

Adaptation and Self-Organizing Systems · Physics 2012-06-29 Jeppe Juul , Kim Sneppen

We study the spread of multi-competitive viruses over a (possibly) time-varying network of individuals accounting for the presence of shared infrastructure networks that further enables transmission of the virus. We establish a sufficient…

Systems and Control · Electrical Eng. & Systems 2023-03-17 Sebin Gracy , Yuan Wang , Philip E. Pare , Cesar A Uribe

A number of studies have suggested using comparisons between DNA sequences of closely related bacterial isolates to estimate the relative rate of recombination to mutation for that bacterial species. We consider such an approach which uses…

Applications · Statistics 2015-06-03 Paul Fearnhead , Shoukai Yu , Patrick Biggs , Barbara Holland , Nigel French

The viral load is known to be a chief predictor of the risk of transmission of infectious diseases. In this work, we investigate the role of the individuals' viral load in the disease transmission by proposing a new…

Adaptation and Self-Organizing Systems · Physics 2023-03-29 Rossella Della Marca , Nadia Loy , Andrea Tosin

We consider a single genetic locus with two alleles $A_1$ and $A_2$ in a large haploid population. The locus is subject to selection and two-way, or recurrent, mutation. Assuming the allele frequencies follow a Wright-Fisher diffusion and…

Probability · Mathematics 2024-04-29 Wai-Tong Louis Fan , John Wakeley

We present an epidemiological model for vector-borne diseases that includes within-host viral load and antibody dynamics using structured transport equations. By incorporating the internal dynamics into the infected and recovered host…

Analysis of PDEs · Mathematics 2026-05-26 Paulo Amorim , Maria Soledad Aronna , Debora de Oliveira Medeiros

We define and examine a model of epidemic propagation for a virus such as Hepatitis C (with HIV co-infection) on a network of networks, namely the network of French urban areas. One network level is that of the individual interactions…

Physics and Society · Physics 2017-05-24 Arnaud Nucit , Julien Randon-Furling

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

Popular Physics · Physics 2021-02-03 F. Marin , C. Beluffi , F. Fischer

Measuring gene expression simultaneously in both hosts and symbionts offers a powerful approach to explore the biology underlying species interactions. Such dual or simultaneous RNAseq approaches have primarily been used to gain insight…

Populations and Evolution · Quantitative Biology 2022-06-28 Amanda K Hund , Peter Tiffin , Jean-Gabriel Young , Daniel I Bolnick

We investigate a model for a mosquito-borne epidemic in which human hosts may adopt protective behaviour against vector bites in response to information on both past and current disease prevalence. Assuming that mosquitoes can also feed on…

Populations and Evolution · Quantitative Biology 2026-05-08 Simone De Reggi , Andrea Pugliese , Mattia Sensi , Cinzia Soresina

This study extends the SIS epidemic model for single virus propagation over an arbitrary graph to an SI1SI2S epidemic model of two exclusive, competitive viruses over a two-layer network with generic structure, where network layers…

Physics and Society · Physics 2013-09-02 Faryad Darabi Sahneh , Caterina Scoglio