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Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Extracting temporal relations between events and time expressions has many applications such as constructing event timelines and time-related question answering. It is a challenging problem which requires syntactic and semantic information…

Computation and Language · Computer Science 2020-10-06 Hayley Ross , Jonathon Cai , Bonan Min

The work in this paper evaluates zero-shot and few-shot large language models (LLMs) for safety-critical clinical action extraction using the CLIP discharge-note dataset, with particular emphasis on transitions of care and post-discharge…

Artificial Intelligence · Computer Science 2026-05-08 Shivali Dalmia , Ananya Mantravadi , Prasanna Desikan

This work presents biomedical and clinical language models for Spanish by experimenting with different pretraining choices, such as masking at word and subword level, varying the vocabulary size and testing with domain data, looking for…

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Foundation Models (FMs) trained on Electronic Health Records (EHRs) have achieved state-of-the-art results on numerous clinical prediction tasks. However, most existing EHR FMs have context windows of <1k tokens. This prevents them from…

Accurate extraction of breast cancer patients' phenotypes is important for clinical decision support and clinical research. Current models do not take full advantage of cancer domain-specific corpus, whether pre-training Bidirectional…

Information Retrieval · Computer Science 2022-03-10 Sicheng Zhou , Liwei Wang , Nan Wang , Hongfang Liu , Rui Zhang

Clinical notes are unstructured text generated by clinicians during patient encounters. Clinical notes are usually accompanied by a set of metadata codes from the International Classification of Diseases(ICD). ICD code is an important code…

Artificial Intelligence · Computer Science 2021-11-12 Tak-Sung Heo , Yongmin Yoo , Yeongjoon Park , Byeong-Cheol Jo , Kyungsun Kim

This study explores the potential of natural language models, including large language models, to extract causal relations from medical texts, specifically from Clinical Practice Guidelines (CPGs). The outcomes causality extraction from…

Computation and Language · Computer Science 2024-07-16 Seethalakshmi Gopalakrishnan , Luciana Garbayo , Wlodek Zadrozny

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome…

Computation and Language · Computer Science 2023-01-30 Yanjun Gao , Dmitriy Dligach , Timothy Miller , John Caskey , Brihat Sharma , Matthew M Churpek , Majid Afshar

Entity recognition is a critical first step to a number of clinical NLP applications, such as entity linking and relation extraction. We present the first attempt to apply state-of-the-art entity recognition approaches on a newly released…

Computation and Language · Computer Science 2019-10-04 Kathleen C. Fraser , Isar Nejadgholi , Berry De Bruijn , Muqun Li , Astha LaPlante , Khaldoun Zine El Abidine

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Understanding deep learning model behavior is critical to accepting machine learning-based decision support systems in the medical community. Previous research has shown that jointly using clinical notes with electronic health record (EHR)…

Machine Learning · Computer Science 2022-12-07 Severin Husmann , Hugo Yèche , Gunnar Rätsch , Rita Kuznetsova

Traditional topic models often struggle with contextual nuances and fail to adequately handle polysemy and rare words. This limitation typically results in topics that lack coherence and quality. Large Language Models (LLMs) can mitigate…

Computation and Language · Computer Science 2025-05-13 Hajar Sakai , Sarah S. Lam

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang
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